Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Fshr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FSHR
- Mouse genes Fshr
- Rat genes Fshr
- Zfish genes fshr
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fshr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	FSHR	IMP		Human	PMID:11847099
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	FSHR	IDA		Human	PMID:24692546
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Mouse	PMID:9206032
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Mouse	PMID:16630814
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Mouse	PMID:10330114
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Rat	PMID:11934883\|RGD:724592
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Rat	PMID:12145341\|RGD:1601255
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Rat	PMID:16598027\|RGD:1601258
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Rat	PMID:16899567\|RGD:4140424
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	Fshr	IDA		Rat	PMID:2126341\|RGD:625417
Molecular Function	GO:0004963	follicle-stimulating hormone receptor activity	fshr	IDA		Zfish	PMID:15728794
Molecular Function	GO:0017046	peptide hormone binding	Fshr	IDA		Rat	PMID:16899567\|RGD:4140424
Molecular Function	GO:0005515	protein binding	FSHR	IPI	UniProtKB:P27348	Human	PMID:15196694
Molecular Function	GO:0005515	protein binding	FSHR	IPI	UniProtKB:Q12778	Human	PMID:17030088
Molecular Function	GO:0005515	protein binding	FSHR	IPI	UniProtKB:Q8NEU8	Human	PMID:17030088
Molecular Function	GO:0005515	protein binding	FSHR	IPI	UniProtKB:P27348	Human	PMID:20600589
Molecular Function	GO:0005515	protein binding	Fshr	IPI	RGD:1350252	Rat	PMID:11934883\|RGD:724592
Molecular Function	GO:0005515	protein binding	Fshr	IPI	RGD:2156\|RGD:2157	Rat	PMID:16899567\|RGD:4140424
Cellular Component	GO:0009986	cell surface	Fshr	IDA		Mouse	PMID:16630814
Cellular Component	GO:0009986	cell surface	Fshr	IDA		Rat	PMID:11934883\|RGD:724592
Cellular Component	GO:0009986	cell surface	Fshr	IDA		Rat	PMID:12907758\|RGD:1601256
Cellular Component	GO:0005768	endosome	Fshr	IDA		Rat	PMID:12907758\|RGD:1601256
Cellular Component	GO:0016020	membrane	FSHR	IDA		Human	PMID:24692546
Cellular Component	GO:0005886	plasma membrane	FSHR	IDA		Human	PMID:11847099
Cellular Component	GO:0043235	receptor complex	FSHR	IDA		Human	PMID:24692546
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Fshr	IDA		Rat	PMID:16598027\|RGD:1601258
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Fshr	IDA		Rat	PMID:2126341\|RGD:625417
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Fshr	IDA		Mouse	PMID:16630814
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Fshr	IDA		Mouse	PMID:10330114
Biological Process	GO:0071711	basement membrane organization	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:9811848
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	FSHR	IMP		Human	PMID:11847099
Biological Process	GO:0008585	female gonad development	fshr	IMP	ZFIN:ZDB-GENO-170306-2	Zfish	PMID:26452104
Biological Process	GO:0008585	female gonad development	fshr	IGI	ZFIN:ZDB-GENE-040806-3	Zfish	PMID:26452104
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	FSHR	IMP		Human	PMID:11847099
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	FSHR	IDA		Human	PMID:24692546
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	Fshr	IDA		Mouse	PMID:10330114
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	Fshr	IDA		Rat	PMID:12145341\|RGD:1601255
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	Fshr	IDA		Rat	PMID:16598027\|RGD:1601258
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	Fshr	IDA		Rat	PMID:16899567\|RGD:4140424
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	fshr	IDA		Zfish	PMID:15728794\|ZFIN:ZDB-PUB-050225-11
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	FSHR	IDA		Human	PMID:24692546
Biological Process	GO:0009992	intracellular water homeostasis	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14998910
Biological Process	GO:0007626	locomotory behavior	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14502087
Biological Process	GO:0008584	male gonad development	FSHR	IEP		Human	PMID:17848411
Biological Process	GO:0008584	male gonad development	fshr	IMP	ZFIN:ZDB-GENO-160126-3	Zfish	PMID:25993524
Biological Process	GO:0045779	negative regulation of bone resorption	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:17332067
Biological Process	GO:0045779	negative regulation of bone resorption	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:11089565
Biological Process	GO:0031175	neuron projection development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12204217
Biological Process	GO:0001541	ovarian follicle development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12135868
Biological Process	GO:0001541	ovarian follicle development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12801993
Biological Process	GO:0001541	ovarian follicle development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:9811848
Biological Process	GO:0001541	ovarian follicle development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:11089565
Biological Process	GO:0001541	ovarian follicle development	Fshr	IMP	MGI:MGI:2384130	Mouse	PMID:10803590
Biological Process	GO:0001541	ovarian follicle development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:11459817
Biological Process	GO:0001541	ovarian follicle development	fshr	IMP	ZFIN:ZDB-GENO-160126-1	Zfish	PMID:25993524
Biological Process	GO:0001541	ovarian follicle development	fshr	IMP	ZFIN:ZDB-GENO-170306-2	Zfish	PMID:26452104
Biological Process	GO:0022602	ovulation cycle process	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:11089565
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Fshr	IDA		Mouse	PMID:10330114
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	FSHR	IDA		Human	PMID:24058690
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:11089565
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	FSHR	IMP		Human	PMID:24058690
Biological Process	GO:0001545	primary ovarian follicle growth	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12801993
Biological Process	GO:0060408	regulation of acetylcholine metabolic process	Fshr	IGI	MGI:MGI:88392	Mouse	PMID:12204217
Biological Process	GO:0033044	regulation of chromosome organization	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14680821
Biological Process	GO:0032350	regulation of hormone metabolic process	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12204217
Biological Process	GO:0032350	regulation of hormone metabolic process	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12801993
Biological Process	GO:0032350	regulation of hormone metabolic process	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14502087
Biological Process	GO:0032350	regulation of hormone metabolic process	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14552897
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:18676690
Biological Process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:18063689
Biological Process	GO:0043408	regulation of MAPK cascade	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12204217
Biological Process	GO:0045670	regulation of osteoclast differentiation	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:16630814
Biological Process	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:16344272
Biological Process	GO:0010738	regulation of protein kinase A signaling	FSHR	IMP		Human	PMID:24058690
Biological Process	GO:0001932	regulation of protein phosphorylation	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:12204217
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:18599597
Biological Process	GO:0014070	response to organic cyclic compound	Fshr	IEP		Rat	PMID:28208728\|RGD:151893505
Biological Process	GO:0060009	Sertoli cell development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14998910
Biological Process	GO:0060011	Sertoli cell proliferation	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:11466221
Biological Process	GO:0060011	Sertoli cell proliferation	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:18403489
Biological Process	GO:0035092	sperm DNA condensation	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:10775161
Biological Process	GO:0035092	sperm DNA condensation	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14680821
Biological Process	GO:0007286	spermatid development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:15973687
Biological Process	GO:0007286	spermatid development	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:11466221
Biological Process	GO:0007283	spermatogenesis	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:9811848
Biological Process	GO:0007283	spermatogenesis	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:18403489
Biological Process	GO:0007283	spermatogenesis	Fshr	IMP	MGI:MGI:2384087	Mouse	PMID:14680821
Biological Process	GO:0007283	spermatogenesis	fshr	IGI	ZFIN:ZDB-GENE-040806-3	Zfish	PMID:26452104
Biological Process	GO:0045056	transcytosis	Fshr	IDA		Rat	PMID:15050368\|RGD:1601257
Biological Process	GO:0060065	uterus development	Fshr	IMP	MGI:MGI:2384130	Mouse	PMID:10803590

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.