Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FST
  • Mouse genes Fst
  • Rat genes Fst
  • Zfish genes fsta,fstb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fst

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048185	activin binding	FST	IPI	UniProtKB:P08476	Human	PMID:12697670
Molecular Function	GO:0048185	activin binding	FST	IPI	UniProtKB:P09529	Human	PMID:12697670
Molecular Function	GO:0038102	activin receptor antagonist activity	FST	IMP		Human	PMID:12702211
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	Fst	IDA		Rat	PMID:12867435|RGD:1601260
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:P08476	Human	PMID:16198295
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:P03950	Human	PMID:17991437
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:Q14689	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:P10599	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:Q8NEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:Q8TAU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:Q96SQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FST	IPI	UniProtKB:Q9BXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fst	IPI	UniProtKB:P08476	Rat	PMID:16482217|RGD:8554128
Cellular Component	GO:0005737	cytoplasm	Fst	IDA		Mouse	PMID:20032047
Cellular Component	GO:0005615	extracellular space	Fst	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005634	nucleus	Fst	IDA		Mouse	PMID:20032047
Biological Process	GO:0036305	ameloblast differentiation	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:15525533
Biological Process	GO:0036305	ameloblast differentiation	Fst	IGI	MGI:MGI:88180	Mouse	PMID:15525533
Biological Process	GO:0030509	BMP signaling pathway	Fst	IGI	MGI:MGI:88180	Mouse	PMID:15525533
Biological Process	GO:0071363	cellular response to growth factor stimulus	Fst	IEP		Rat	PMID:23567549|RGD:151893499
Biological Process	GO:0048263	determination of dorsal identity	fsta	IMP		Zfish	PMID:9882485
Biological Process	GO:0009953	dorsal/ventral pattern formation	fsta	IDA		Zfish	PMID:16890217
Biological Process	GO:0009953	dorsal/ventral pattern formation	fsta	IMP		Zfish	PMID:9882485
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	fsta	IMP	ZFIN:ZDB-MRPHLNO-080212-3	Zfish	PMID:23209659
Biological Process	GO:0008585	female gonad development	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:15162500
Biological Process	GO:0007276	gamete generation	Fst	IGI	MGI:MGI:98957	Mouse	PMID:15162500
Biological Process	GO:0031069	hair follicle morphogenesis	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:12514121
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	FST	IDA		Human	PMID:15451575
Biological Process	GO:0043616	keratinocyte proliferation	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:12514121
Biological Process	GO:0030901	midbrain development	fsta	IMP	ZFIN:ZDB-MRPHLNO-100426-5	Zfish	PMID:20194436
Biological Process	GO:0030901	midbrain development	fsta	IMP	ZFIN:ZDB-MRPHLNO-100426-6	Zfish	PMID:20194436
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	FST	IDA		Human	PMID:11948405
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	FST	IDA		Human	PMID:12697670
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	FST	IMP		Human	PMID:12702211
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:15525533
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	Fst	IGI	MGI:MGI:88180	Mouse	PMID:15525533
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FST	IDA		Human	PMID:12702211
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:15305290
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:15525533
Biological Process	GO:0043049	otic placode formation	fsta	IGI	ZFIN:ZDB-MRPHLNO-050221-6,ZFIN:ZDB-MRPHLNO-060320-5,ZFIN:ZDB-MRPHLNO-101102-5	Zfish	PMID:19418450
Biological Process	GO:0007389	pattern specification process	Fst	IMP	MGI:MGI:1857467	Mouse	PMID:15525533
Biological Process	GO:0051798	positive regulation of hair follicle development	FST	IDA		Human	PMID:12514121
Biological Process	GO:0014070	response to organic cyclic compound	Fst	IEP		Rat	PMID:30599193|RGD:151893501
Biological Process	GO:0001501	skeletal system development	Fst	IGI	MGI:MGI:2670967	Mouse	PMID:24019467

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern