Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FSTL1
  • Mouse genes Fstl1
  • Rat genes Fstl1
  • Zfish genes fstl1a,fstl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fstl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:Q92624	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:A4D1W7	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:P01137	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:P08571	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:P12643	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:Q14689	Human	PMID:20860622
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:P08571	Human	PMID:22265692
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FSTL1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Fstl1	IPI	UniProtKB:Q14689	Mouse	MGI:MGI:4457221|PMID:20054002
Cellular Component	GO:0070062	extracellular exosome	FSTL1	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	fstl1a	IDA		Zfish	PMID:11748832
Cellular Component	GO:0005615	extracellular space	FSTL1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Fstl1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0009953	dorsal/ventral pattern formation	fstl1b	IGI	ZFIN:ZDB-MRPHLNO-050221-6,ZFIN:ZDB-MRPHLNO-080212-1,ZFIN:ZDB-MRPHLNO-080214-1	Zfish	PMID:16890217
Biological Process	GO:0009953	dorsal/ventral pattern formation	fstl1b	IGI	ZFIN:ZDB-MRPHLNO-050221-6,ZFIN:ZDB-MRPHLNO-080214-1	Zfish	PMID:16890217
Biological Process	GO:0045446	endothelial cell differentiation	Fstl1	IMP		Mouse	MGI:MGI:4457221|PMID:20054002
Biological Process	GO:0043542	endothelial cell migration	Fstl1	IMP		Mouse	MGI:MGI:4457221|PMID:20054002
Biological Process	GO:0043542	endothelial cell migration	Fstl1	IDA		Mouse	MGI:MGI:4457221|PMID:20054002
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	Fstl1	IMP		Mouse	PMID:26880577
Biological Process	GO:0043066	negative regulation of apoptotic process	Fstl1	IMP		Mouse	MGI:MGI:4457221|PMID:20054002
Biological Process	GO:0060034	notochord cell differentiation	fstl1b	IGI	ZFIN:ZDB-MRPHLNO-090909-6,ZFIN:ZDB-MRPHLNO-090909-7	Zfish	PMID:18948415
Biological Process	GO:0060034	notochord cell differentiation	fstl1a	IGI	ZFIN:ZDB-MRPHLNO-090909-6,ZFIN:ZDB-MRPHLNO-090909-7	Zfish	PMID:18948415
Biological Process	GO:0030903	notochord development	fstl1b	IGI	ZFIN:ZDB-MRPHLNO-090909-6,ZFIN:ZDB-MRPHLNO-090909-7	Zfish	PMID:18948415
Biological Process	GO:0030903	notochord development	fstl1a	IGI	ZFIN:ZDB-MRPHLNO-090909-6,ZFIN:ZDB-MRPHLNO-090909-7	Zfish	PMID:18948415
Biological Process	GO:0030510	regulation of BMP signaling pathway	fstl1b	IGI	ZFIN:ZDB-MRPHLNO-090909-6,ZFIN:ZDB-MRPHLNO-090909-7	Zfish	PMID:18948415
Biological Process	GO:0030510	regulation of BMP signaling pathway	fstl1a	IGI	ZFIN:ZDB-MRPHLNO-090909-6,ZFIN:ZDB-MRPHLNO-090909-7	Zfish	PMID:18948415

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern