Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FSTL3
  • Mouse genes Fstl3
  • Rat genes Fstl3
  • Zfish genes fstl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fstl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048185	activin binding	FSTL3	IPI	UniProtKB:P08476	Human	PMID:12697670
Molecular Function	GO:0048185	activin binding	FSTL3	IPI	UniProtKB:P09529	Human	PMID:12697670
Molecular Function	GO:0048185	activin binding	Fstl3	IDA		Mouse	PMID:11010968
Molecular Function	GO:0001968	fibronectin binding	FSTL3	IPI	UniProtKB:P02751	Human	PMID:16336961
Molecular Function	GO:0005515	protein binding	FSTL3	IPI	UniProtKB:O43184-2	Human	PMID:15574124
Molecular Function	GO:0005515	protein binding	FSTL3	IPI	UniProtKB:P78325	Human	PMID:15574124
Molecular Function	GO:0005515	protein binding	FSTL3	IPI	UniProtKB:P55197	Human	PMID:17868029
Molecular Function	GO:0005515	protein binding	FSTL3	IPI	UniProtKB:P07995	Human	PMID:17878677
Cellular Component	GO:0005615	extracellular space	FSTL3	IDA		Human	PMID:16150905
Cellular Component	GO:0005615	extracellular space	Fstl3	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Fstl3	IDA		Mouse	PMID:11739004
Cellular Component	GO:0005615	extracellular space	Fstl3	IDA		Rat	PMID:14692692|RGD:1302294
Cellular Component	GO:0005794	Golgi apparatus	Fstl3	IDA		Rat	PMID:14692692|RGD:1302294
Cellular Component	GO:0044306	neuron projection terminus	Fstl3	IDA		Rat	PMID:14692692|RGD:1302294
Cellular Component	GO:0005654	nucleoplasm	FSTL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FSTL3	IDA		Human	PMID:16150905
Cellular Component	GO:0030141	secretory granule	Fstl3	IDA		Rat	PMID:14692692|RGD:1302294
Biological Process	GO:0030325	adrenal gland development	Fstl3	IEP		Rat	PMID:14692692|RGD:1302294
Biological Process	GO:0071248	cellular response to metal ion	Fstl3	IEP		Rat	PMID:14692692|RGD:1302294
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	FSTL3	IDA		Human	PMID:15451575
Biological Process	GO:0001822	kidney development	Fstl3	IEP		Rat	PMID:14692692|RGD:1302294
Biological Process	GO:0030324	lung development	Fstl3	IEP		Rat	PMID:14692692|RGD:1302294
Biological Process	GO:0008584	male gonad development	Fstl3	IEP		Rat	PMID:14692692|RGD:1302294
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	FSTL3	IDA		Human	PMID:11948405
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	FSTL3	IDA		Human	PMID:12697670
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	FSTL3	IDA		Human	PMID:17878677
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	Fstl3	IDA		Mouse	PMID:11010968
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	FSTL3	IDA		Human	PMID:15574124
Biological Process	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	FSTL3	IDA		Human	PMID:17878677
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	FSTL3	IDA		Human	PMID:16336961
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FSTL3	IDA		Human	PMID:17868029
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	FSTL3	IDA		Human	PMID:11948405
Biological Process	GO:0007283	spermatogenesis	Fstl3	IEP		Rat	PMID:14692692|RGD:1302294

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern