Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FTL
  • Mouse genes Ftl1
  • Rat genes LOC102549852
  • Zfish genes zgc:56095
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ftl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	FTL	IPI	UniProtKB:P02792	Human	PMID:16169070
Molecular Function	GO:0042802	identical protein binding	FTL	IPI	UniProtKB:P02792	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	FTL	IPI	UniProtKB:P02792	Human	PMID:16790936
Molecular Function	GO:0042802	identical protein binding	FTL	IPI	UniProtKB:P02792	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	FTL	IPI	UniProtKB:P02792	Human	PMID:25502805
Molecular Function	GO:0042802	identical protein binding	FTL	IPI	UniProtKB:P02792	Human	PMID:25910212
Molecular Function	GO:0042802	identical protein binding	FTL	IPI	UniProtKB:P02792	Human	PMID:31515488
Molecular Function	GO:0005506	iron ion binding	FTL	IDA		Human	PMID:19923220
Molecular Function	GO:0005506	iron ion binding	FTL	IDA		Human	PMID:20159981
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P02794	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P02794	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:Q9NRJ1	Human	PMID:17143515
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P43490	Human	PMID:18486613
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P02794	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P42858	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:Q9NZ42	Human	PMID:23685131
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:O00505	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P02794	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P15173	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:Q6NZ44	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P02794	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P02794	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P02794	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P15173	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P49768-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P49810	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FTL	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ftl1	IPI	UniProtKB:Q8K299	Mouse	MGI:MGI:3833042|PMID:19154717
Cellular Component	GO:0044754	autolysosome	FTL	IDA		Human	PMID:25327288
Cellular Component	GO:0070062	extracellular exosome	FTL	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FTL	HDA		Human	PMID:23533145
Cellular Component	GO:0008043	intracellular ferritin complex	FTL	IDA		Human	PMID:19923220
Cellular Component	GO:0008043	intracellular ferritin complex	FTL	IDA		Human	PMID:20159981
Cellular Component	GO:0016020	membrane	FTL	HDA		Human	PMID:19946888

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern