Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FUT8
  • Mouse genes Fut8
  • Rat genes Fut8
  • Zfish genes fut8a,fut8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fut8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046921	alpha-(1->6)-fucosyltransferase activity	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:16236725
Molecular Function	GO:0046921	alpha-(1->6)-fucosyltransferase activity	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:17043354
Molecular Function	GO:0046921	alpha-(1->6)-fucosyltransferase activity	fut8a	IMP	ZFIN:ZDB-MRPHLNO-090616-23	Zfish	PMID:21069830
Molecular Function	GO:0046921	alpha-(1->6)-fucosyltransferase activity	fut8a	IMP	ZFIN:ZDB-MRPHLNO-101207-1	Zfish	PMID:21069830
Molecular Function	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity	FUT8	IDA		Human	PMID:17172260
Molecular Function	GO:0005515	protein binding	FUT8	IPI	UniProtKB:Q96DT7-3	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	FUT8	HDA		Human	PMID:19199708
Cellular Component	GO:0016020	membrane	FUT8	HDA		Human	PMID:19946888
Biological Process	GO:0016477	cell migration	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:17043354
Biological Process	GO:0010761	fibroblast migration	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:17043354
Biological Process	GO:0046368	GDP-L-fucose metabolic process	FUT8	IDA		Human	PMID:17172260
Biological Process	GO:0007229	integrin-mediated signaling pathway	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:17043354
Biological Process	GO:0036071	N-glycan fucosylation	Fut8	IMP		Mouse	PMID:24619415
Biological Process	GO:0036071	N-glycan fucosylation	fut8a	IMP	ZFIN:ZDB-MRPHLNO-090616-23	Zfish	PMID:21069830
Biological Process	GO:0036071	N-glycan fucosylation	fut8a	IMP	ZFIN:ZDB-MRPHLNO-101207-1	Zfish	PMID:21069830
Biological Process	GO:0006491	N-glycan processing	Fut8	IMP		Mouse	PMID:24619415
Biological Process	GO:0018279	protein N-linked glycosylation via asparagine	FUT8	IDA		Human	PMID:17172260
Biological Process	GO:0043112	receptor metabolic process	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:16236725
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	Fut8	IMP		Mouse	PMID:24619415
Biological Process	GO:0010468	regulation of gene expression	Fut8	IMP		Mouse	PMID:24619415
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:16236725
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Fut8	IMP	MGI:MGI:3608699	Mouse	PMID:16236725

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern