Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FXYD1
  • Mouse genes Fxyd1
  • Rat genes Fxyd1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fxyd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	Fxyd1	IDA		Rat	PMID:23532852|RGD:9685469
Molecular Function	GO:0017022	myosin binding	Fxyd1	IDA		Rat	PMID:23532852|RGD:9685469
Molecular Function	GO:0005515	protein binding	Fxyd1	IPI	RGD:3717	Rat	PMID:15774479|RGD:1581354
Molecular Function	GO:0017080	sodium channel regulator activity	Fxyd1	IMP		Mouse	MGI:MGI:5582172|PMID:17095720
Molecular Function	GO:0017080	sodium channel regulator activity	Fxyd1	IMP		Mouse	MGI:MGI:3575337|PMID:15563542
Cellular Component	GO:0016324	apical plasma membrane	Fxyd1	IDA		Rat	PMID:12657675|RGD:12907559
Cellular Component	GO:0005901	caveola	Fxyd1	IDA		Rat	PMID:23532852|RGD:9685469
Cellular Component	GO:0014704	intercalated disc	Fxyd1	IDA		Rat	PMID:23532852|RGD:9685469
Cellular Component	GO:0005886	plasma membrane	Fxyd1	IDA		Rat	PMID:12657562|RGD:9685465
Cellular Component	GO:0042383	sarcolemma	Fxyd1	IMP		Mouse	MGI:MGI:3575337|PMID:15563542
Cellular Component	GO:0042383	sarcolemma	Fxyd1	IDA		Rat	PMID:15961612|RGD:9685467
Cellular Component	GO:0030315	T-tubule	Fxyd1	IDA		Rat	PMID:23532852|RGD:9685469
Biological Process	GO:0007420	brain development	Fxyd1	IEP		Rat	PMID:19187398|RGD:9685458
Biological Process	GO:1903797	positive regulation of inorganic anion transmembrane transport	Fxyd1	IMP		Rat	PMID:11336802|RGD:9685470
Biological Process	GO:0032892	positive regulation of organic acid transport	Fxyd1	IMP		Rat	PMID:11336802|RGD:9685470
Biological Process	GO:1903278	positive regulation of sodium ion export across plasma membrane	Fxyd1	IMP		Mouse	MGI:MGI:5582172|PMID:17095720
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction	Fxyd1	IMP		Rat	PMID:14684371|RGD:9685468
Biological Process	GO:0086036	regulation of cardiac muscle cell membrane potential	Fxyd1	IMP		Mouse	MGI:MGI:5582172|PMID:17095720
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Fxyd1	IMP		Rat	PMID:14684371|RGD:9685468
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	Fxyd1	IMP		Mouse	MGI:MGI:3575337|PMID:15563542
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	Fxyd1	IMP		Mouse	MGI:MGI:5582172|PMID:17095720

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern