Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FXYD2
  • Mouse genes Fxyd2
  • Rat genes Fxyd2
  • Zfish genes fxyd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fxyd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Fxyd2	IPI	RGD:2167	Rat	PMID:16373350|RGD:1598988
Molecular Function	GO:0005515	protein binding	Fxyd2	IPI	RGD:70998	Rat	PMID:16373350|RGD:1598988
Molecular Function	GO:0017080	sodium channel regulator activity	Fxyd2	IMP	MGI:MGI:3586329	Mouse	PMID:15755730
Cellular Component	GO:0016323	basolateral plasma membrane	Fxyd2	IDA		Rat	PMID:16757733|RGD:1598987
Cellular Component	GO:0070062	extracellular exosome	FXYD2	HDA		Human	PMID:19056867
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Fxyd2	IDA		Rat	PMID:11832419|RGD:631313
Cellular Component	GO:0016020	membrane	Fxyd2	IDA		Mouse	PMID:15755730
Cellular Component	GO:0005886	plasma membrane	Fxyd2	IDA		Rat	PMID:15280368|RGD:1598989
Cellular Component	GO:0005890	sodium:potassium-exchanging ATPase complex	Fxyd2	IDA		Rat	PMID:12626497|RGD:1598991
Biological Process	GO:0071475	cellular hyperosmotic salinity response	Fxyd2	IEP		Rat	PMID:15280368|RGD:1598989
Biological Process	GO:0098662	inorganic cation transmembrane transport	Fxyd2	IDA		Rat	PMID:12626497|RGD:1598991
Biological Process	GO:0008285	negative regulation of cell population proliferation	Fxyd2	IMP		Rat	PMID:15280368|RGD:1598989
Biological Process	GO:1903407	negative regulation of P-type sodium:potassium-exchanging transporter activity	Fxyd2	IMP		Rat	PMID:15280368|RGD:1598989
Biological Process	GO:1903406	regulation of P-type sodium:potassium-exchanging transporter activity	Fxyd2	IDA		Rat	PMID:11756431|RGD:625472
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	Fxyd2	IMP	MGI:MGI:3586329	Mouse	PMID:15755730

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern