Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Fzd3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FZD3
- Mouse genes Fzd3
- Rat genes Fzd3
- Zfish genes fzd3a,fzd3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fzd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	FZD3	IPI	UniProtKB:O00560	Human	PMID:18256285
Molecular Function	GO:0030165	PDZ domain binding	FZD3	IPI	UniProtKB:O14640	Human	PMID:19388021
Molecular Function	GO:0030165	PDZ domain binding	FZD3	IPI	UniProtKB:O14641	Human	PMID:19388021
Molecular Function	GO:0030165	PDZ domain binding	FZD3	IPI	UniProtKB:Q92997	Human	PMID:19388021
Molecular Function	GO:0005515	protein binding	FZD3	IPI	UniProtKB:Q8N474	Human	PMID:19277043
Molecular Function	GO:0005515	protein binding	Fzd3	IPI	UniProtKB:Q91ZD4	Mouse	MGI:MGI:3624469\|PMID:16687519
Molecular Function	GO:0005515	protein binding	Fzd3	IPI	PR:Q9D1D6	Mouse	PMID:18606138
Molecular Function	GO:0042813	Wnt receptor activity	Fzd3	IMP		Mouse	MGI:MGI:4866939\|PMID:21106844
Molecular Function	GO:0017147	Wnt-protein binding	FZD3	IPI	UniProtKB:P09544	Human	PMID:19038973
Cellular Component	GO:0045177	apical part of cell	Fzd3	IDA		Mouse	PMID:16687519
Cellular Component	GO:0045177	apical part of cell	Fzd3	IDA		Mouse	PMID:19300477
Cellular Component	GO:0045177	apical part of cell	Fzd3	IDA		Mouse	PMID:16495441
Cellular Component	GO:0016324	apical plasma membrane	Fzd3	IDA		Mouse	PMID:20016102
Cellular Component	GO:0030424	axon	Fzd3	IDA		Mouse	MGI:MGI:4820709\|PMID:18986540
Cellular Component	GO:0005737	cytoplasm	FZD3	IDA		Human	PMID:19038973
Cellular Component	GO:0030425	dendrite	Fzd3	IDA		Mouse	MGI:MGI:4820709\|PMID:18986540
Cellular Component	GO:0032433	filopodium tip	Fzd3	IDA		Mouse	PMID:24305805
Cellular Component	GO:0016328	lateral plasma membrane	Fzd3	IDA		Mouse	PMID:20473291
Cellular Component	GO:0043025	neuronal cell body	Fzd3	IDA		Mouse	MGI:MGI:4820709\|PMID:18986540
Cellular Component	GO:0005886	plasma membrane	FZD3	IDA		Human	PMID:19038973
Cellular Component	GO:0005886	plasma membrane	Fzd3	IDA		Mouse	MGI:MGI:3621833\|PMID:15035989
Cellular Component	GO:0005886	plasma membrane	Fzd3	IDA		Mouse	PMID:20016102
Cellular Component	GO:0005886	plasma membrane	Fzd3	IDA		Mouse	PMID:19966784
Cellular Component	GO:0048786	presynaptic active zone	Fzd3	IDA		Mouse	MGI:MGI:4820709\|PMID:18986540
Biological Process	GO:0033564	anterior/posterior axon guidance	fzd3a	IMP	ZFIN:ZDB-GENO-170328-1	Zfish	PMID:27955617
Biological Process	GO:0007420	brain development	Fzd3	IEP		Rat	PMID:16258230\|RGD:8693714
Biological Process	GO:0060070	canonical Wnt signaling pathway	FZD3	IDA		Human	PMID:20802536
Biological Process	GO:0033278	cell proliferation in midbrain	Fzd3	IGI	MGI:MGI:108474	Mouse	PMID:19842188
Biological Process	GO:0071679	commissural neuron axon guidance	Fzd3	IMP	MGI:MGI:2388632	Mouse	PMID:14671310
Biological Process	GO:0071679	commissural neuron axon guidance	fzd3a	IMP	ZFIN:ZDB-GENO-170328-1	Zfish	PMID:27955617
Biological Process	GO:0071679	commissural neuron axon guidance	fzd3a	IMP	ZFIN:ZDB-MRPHLNO-120810-2	Zfish	PMID:23438515
Biological Process	GO:0071679	commissural neuron axon guidance	fzd3a	IGI	ZFIN:ZDB-MRPHLNO-070116-1,ZFIN:ZDB-MRPHLNO-120810-2	Zfish	PMID:23438515
Biological Process	GO:0036514	dopaminergic neuron axon guidance	Fzd3	IMP		Mouse	MGI:MGI:4866939\|PMID:21106844
Biological Process	GO:0001736	establishment of planar polarity	Fzd3	IGI	MGI:MGI:108474	Mouse	PMID:16495441
Biological Process	GO:0021754	facial nucleus development	fzd3a	IMP	ZFIN:ZDB-GENO-070119-5	Zfish	PMID:17079269
Biological Process	GO:0001942	hair follicle development	Fzd3	IEP		Mouse	MGI:MGI:2135857\|PMID:11407985
Biological Process	GO:0042472	inner ear morphogenesis	Fzd3	IGI	MGI:MGI:108474	Mouse	PMID:16495441
Biological Process	GO:0030901	midbrain development	Fzd3	IGI	MGI:MGI:108474	Mouse	PMID:19842188
Biological Process	GO:0097475	motor neuron migration	Fzd3	IMP	MGI:MGI:2388632	Mouse	PMID:20631168
Biological Process	GO:1900118	negative regulation of execution phase of apoptosis	Fzd3	IMP		Mouse	MGI:MGI:4941059\|PMID:21325504
Biological Process	GO:0045976	negative regulation of mitotic cell cycle, embryonic	Fzd3	IMP		Mouse	MGI:MGI:4941059\|PMID:21325504
Biological Process	GO:0001843	neural tube closure	Fzd3	IGI	MGI:MGI:108474	Mouse	PMID:16495441
Biological Process	GO:1904938	planar cell polarity pathway involved in axon guidance	Fzd3	IMP		Mouse	MGI:MGI:4866939\|PMID:21106844
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Fzd3	IMP		Mouse	MGI:MGI:4941059\|PMID:21325504
Biological Process	GO:0036342	post-anal tail morphogenesis	Fzd3	IMP		Mouse	PMID:21746835
Biological Process	GO:0051602	response to electrical stimulus	Fzd3	IEP		Rat	PMID:16258230\|RGD:8693714
Biological Process	GO:0009410	response to xenobiotic stimulus	Fzd3	IEP		Rat	PMID:16258230\|RGD:8693714
Biological Process	GO:0009410	response to xenobiotic stimulus	Fzd3	IEP	CHEBI:9123	Rat	PMID:16258230\|RGD:8693714
Biological Process	GO:0036515	serotonergic neuron axon guidance	Fzd3	IMP		Mouse	MGI:MGI:4866939\|PMID:21106844
Biological Process	GO:0061549	sympathetic ganglion development	Fzd3	IMP		Mouse	MGI:MGI:4941059\|PMID:21325504

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.