Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes G6PC2
  • Mouse genes G6pc2
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set G6pc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004346	glucose-6-phosphatase activity	G6PC2	EXP		Human	PMID:14722102
Molecular Function	GO:0004346	glucose-6-phosphatase activity	G6pc2	IDA		Mouse	PMID:14722102
Molecular Function	GO:0004346	glucose-6-phosphatase activity	G6pc2	IMP	MGI:MGI:3819785	Mouse	PMID:23274894
Cellular Component	GO:0005783	endoplasmic reticulum	G6pc2	IDA		Mouse	PMID:10787428
Biological Process	GO:0042593	glucose homeostasis	G6PC2	IMP		Human	PMID:20668700
Biological Process	GO:0050796	regulation of insulin secretion	G6PC2	IMP		Human	PMID:20668700

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern