Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse G6pdx

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes G6PD
- Mouse genes G6pdx
- Rat genes G6pd
- Zfish genes g6pd
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set G6pdx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	G6pd	IDA		Rat	PMID:2843500\|RGD:1599574
Molecular Function	GO:0005536	glucose binding	G6PD	IDA		Human	PMID:15858258
Molecular Function	GO:0005536	glucose binding	G6PD	IMP		Human	PMID:5643703
Molecular Function	GO:0005536	glucose binding	G6pd	IMP		Rat	PMID:16325866\|RGD:1624987
Molecular Function	GO:0005536	glucose binding	G6pd	IDA		Rat	PMID:17447164\|RGD:1624966
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6PD	IDA		Human	PMID:15858258
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6PD	IMP		Human	PMID:2420826
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6PD	IMP		Human	PMID:5643703
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6PD	IMP		Human	PMID:743300
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:22829586
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP		Mouse	PMID:12466018
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:7439685
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP		Mouse	PMID:15271799
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:14751857
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:943046
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:10627286
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:5764873
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:12521604
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:9627357
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:14757696
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:3377761
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:1953691
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:9067418
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:15155459
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:8491670
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IMP	MGI:MGI:2387672	Mouse	PMID:7489710
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:9330624
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:9539108
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:15998684
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:9169132
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pdx	IDA		Mouse	PMID:3243423
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IDA		Rat	PMID:11735100\|RGD:2317316
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IMP		Rat	PMID:16325866\|RGD:1624987
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IDA		Rat	PMID:17447164\|RGD:1624966
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IDA		Rat	PMID:18062843\|RGD:2317315
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IDA		Rat	PMID:1834654\|RGD:1599371
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IDA		Rat	PMID:21569266\|RGD:10047183
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IDA		Rat	PMID:21930213\|RGD:10047267
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	G6pd	IDA		Rat	PMID:2843500\|RGD:1599574
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	g6pd	IMP	ZFIN:ZDB-MRPHLNO-140311-4,ZFIN:ZDB-MRPHLNO-140311-5	Zfish	PMID:29317613
Molecular Function	GO:0042802	identical protein binding	G6PD	IPI	UniProtKB:P11413	Human	PMID:24769394
Molecular Function	GO:0042802	identical protein binding	G6PD	IPI	UniProtKB:P11413	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	G6pdx	IPI	PR:Q00612	Mouse	PMID:9169132
Molecular Function	GO:0050661	NADP binding	G6PD	IDA		Human	PMID:15858258
Molecular Function	GO:0050661	NADP binding	G6pd	IMP		Rat	PMID:16325866\|RGD:1624987
Molecular Function	GO:0050661	NADP binding	G6pd	IDA		Rat	PMID:17447164\|RGD:1624966
Molecular Function	GO:0005515	protein binding	G6PD	IPI	UniProtKB:P04792	Human	PMID:21157431
Molecular Function	GO:0005515	protein binding	G6PD	IPI	UniProtKB:Q8IXJ6	Human	PMID:24769394
Molecular Function	GO:0042803	protein homodimerization activity	G6PD	IPI	UniProtKB:P11413	Human	PMID:15858258
Molecular Function	GO:0003979	UDP-glucose 6-dehydrogenase activity	g6pd	IMP	ZFIN:ZDB-CRISPR-190115-7	Zfish	PMID:30279493
Cellular Component	GO:0034451	centriolar satellite	G6PD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	G6PD	IDA		Human	GO_REF:0000054
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	G6PD	IDA		Human	PMID:743300
Cellular Component	GO:0005829	cytosol	G6PD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	G6PD	IDA		Human	PMID:743300
Cellular Component	GO:0005829	cytosol	G6pdx	IDA		Mouse	PMID:12466018
Cellular Component	GO:0005829	cytosol	G6pdx	IDA		Mouse	PMID:23029187
Cellular Component	GO:0005829	cytosol	G6pd	IDA		Rat	PMID:1834654\|RGD:1599371
Cellular Component	GO:0070062	extracellular exosome	G6PD	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	G6PD	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	G6PD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	G6pd	IDA		Rat	PMID:2843500\|RGD:1599574
Cellular Component	GO:0016020	membrane	G6PD	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	G6pd	IDA		Rat	PMID:15942958\|RGD:1598733
Biological Process	GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15998684
Biological Process	GO:0002033	angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15998684
Biological Process	GO:0034599	cellular response to oxidative stress	G6PD	IMP		Human	PMID:17516514
Biological Process	GO:0006695	cholesterol biosynthetic process	G6PD	IMP		Human	PMID:12027950
Biological Process	GO:0001816	cytokine production	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15817708
Biological Process	GO:0090504	epiboly	g6pd	IMP	ZFIN:ZDB-MRPHLNO-140311-4,ZFIN:ZDB-MRPHLNO-140311-5	Zfish	PMID:29317613
Biological Process	GO:0048821	erythrocyte development	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:14751857
Biological Process	GO:0048821	erythrocyte development	G6pdx	IMP		Mouse	PMID:15271799
Biological Process	GO:0043249	erythrocyte maturation	G6PD	IMP		Human	PMID:5643703
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	G6PD	IDA		Human	PMID:15858258
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	G6PD	IMP		Human	PMID:5643703
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	G6pd	IMP		Rat	PMID:16325866\|RGD:1624987
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	G6pd	IDA		Rat	PMID:17447164\|RGD:1624966
Biological Process	GO:0006749	glutathione metabolic process	G6PD	IMP		Human	PMID:17516514
Biological Process	GO:0006749	glutathione metabolic process	G6PD	IMP		Human	PMID:2420826
Biological Process	GO:0006749	glutathione metabolic process	G6pdx	IMP	MGI:MGI:2183760	Mouse	PMID:12521604
Biological Process	GO:0032613	interleukin-10 production	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15817708
Biological Process	GO:0032615	interleukin-12 production	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15817708
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IDA		Mouse	PMID:9330624
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:14757696
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IDA		Mouse	PMID:7439685
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:1953691
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IDA		Mouse	PMID:9169132
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15998684
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IDA		Mouse	PMID:9539108
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IDA		Mouse	PMID:9627357
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:9067418
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IMP		Mouse	PMID:15271799
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:3377761
Biological Process	GO:0006741	NADP biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:10627286
Biological Process	GO:0006739	NADP metabolic process	G6PD	IDA		Human	PMID:15858258
Biological Process	GO:0006740	NADPH regeneration	G6PD	IMP		Human	PMID:17516514
Biological Process	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	G6pd	IMP		Rat	PMID:24190878\|RGD:10449133
Biological Process	GO:0010734	negative regulation of protein glutathionylation	G6PD	IMP		Human	PMID:17516514
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	G6pd	IMP		Rat	PMID:24190878\|RGD:10449133
Biological Process	GO:0019322	pentose biosynthetic process	G6PD	IDA		Human	PMID:5643703
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IDA		Mouse	PMID:9539108
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15998684
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:1953691
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:14757696
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IDA		Mouse	PMID:9330624
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IDA		Mouse	PMID:7439685
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IDA		Mouse	PMID:9627357
Biological Process	GO:0019322	pentose biosynthetic process	G6pdx	IDA		Mouse	PMID:8491670
Biological Process	GO:0006098	pentose-phosphate shunt	G6PD	IDA		Human	PMID:2297768
Biological Process	GO:0006098	pentose-phosphate shunt	G6pd	IDA		Rat	PMID:2843500\|RGD:1599574
Biological Process	GO:0009051	pentose-phosphate shunt, oxidative branch	G6PD	IMP		Human	PMID:2420826
Biological Process	GO:0009051	pentose-phosphate shunt, oxidative branch	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:22829586
Biological Process	GO:0009051	pentose-phosphate shunt, oxidative branch	G6pdx	IMP		Mouse	PMID:12466018
Biological Process	GO:0009051	pentose-phosphate shunt, oxidative branch	G6pd	IMP		Rat	PMID:9794092\|RGD:1641793
Biological Process	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	G6pd	IMP		Rat	PMID:23071515\|RGD:10449126
Biological Process	GO:0040014	regulation of multicellular organism growth	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:10627286
Biological Process	GO:0043523	regulation of neuron apoptotic process	G6pd	IDA		Rat	PMID:12414804\|RGD:632733
Biological Process	GO:0045471	response to ethanol	G6pd	IDA		Rat	PMID:18488910\|RGD:2307354
Biological Process	GO:0032094	response to food	G6pd	IEP		Rat	PMID:19076169\|RGD:2307351
Biological Process	GO:0010041	response to iron(III) ion	G6pd	IEP		Rat	PMID:24599681\|RGD:10449122
Biological Process	GO:0014070	response to organic cyclic compound	G6pd	IEP		Rat	PMID:17250641\|RGD:2307361
Biological Process	GO:0006979	response to oxidative stress	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:10627286
Biological Process	GO:0006979	response to oxidative stress	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:14757696
Biological Process	GO:0006979	response to oxidative stress	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15998684
Biological Process	GO:0006979	response to oxidative stress	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:14751857
Biological Process	GO:0006979	response to oxidative stress	G6pdx	IMP	MGI:MGI:2387672	Mouse	PMID:7489710
Biological Process	GO:0006979	response to oxidative stress	G6pdx	IMP	MGI:MGI:2182739	Mouse	PMID:15817708
Biological Process	GO:0046390	ribose phosphate biosynthetic process	G6PD	IMP		Human	PMID:2420826
Biological Process	GO:0021762	substantia nigra development	G6PD	HEP		Human	PMID:22926577

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.