Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gabbr1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GABBR1
- Mouse genes Gabbr1
- Rat genes Gabbr1
- Zfish genes gabbr1a,gabbr1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabbr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990430	extracellular matrix protein binding	Gabbr1	IMP		Rat	PMID:15304491\|RGD:12793050
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	GABBR1	IDA		Human	PMID:9872316
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	GABBR1	IDA		Human	PMID:10328880
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	Gabbr1	IDA		Rat	PMID:10457184\|RGD:632816
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	Gabbr1	IMP		Rat	PMID:12054677\|RGD:625463
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	Gabbr1	IMP		Mouse	PMID:11498050
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	Gabbr1	EXP		Mouse	PMID:11498050
Molecular Function	GO:0099579	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	Gabbr1	IDA		Mouse	PMID:11498050
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	Gabbr1	IDA		Mouse	PMID:10075644
Molecular Function	GO:0150047	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	Gabbr1	IMP		Mouse	PMID:10075644
Molecular Function	GO:0005515	protein binding	GABBR1	IPI	UniProtKB:O75899	Human	PMID:16724110
Molecular Function	GO:0005515	protein binding	GABBR1	IPI	UniProtKB:P46459	Human	PMID:16724110
Molecular Function	GO:0005515	protein binding	GABBR1	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	GABBR1	IPI	UniProtKB:P61244	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	GABBR1	IPI	UniProtKB:O75899	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	GABBR1	IPI	UniProtKB:O15354	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GABBR1	IPI	UniProtKB:O75899	Human	PMID:32555460
Molecular Function	GO:0005515	protein binding	Gabbr1	IPI	PR:Q06507	Mouse	PMID:15013631
Molecular Function	GO:0005515	protein binding	Gabbr1	IPI	PR:Q6WVG3	Mouse	PMID:20400944
Molecular Function	GO:0005515	protein binding	Gabbr1	IPI	RGD:620833	Rat	PMID:17241134\|RGD:2315460
Molecular Function	GO:0005515	protein binding	Gabbr1	IPI	RGD:1562401	Rat	PMID:17668444\|RGD:2315466
Molecular Function	GO:0005515	protein binding	Gabbr1	IPI	UniProtKB:O88871	Rat	PMID:19590495\|RGD:8553550
Molecular Function	GO:0005515	protein binding	Gabbr1	IPI	UniProtKB:O88871	Rat	PMID:21063387\|RGD:8553604
Molecular Function	GO:0005515	protein binding	Gabbr1	IPI	UniProtKB:O88871	Rat	PMID:21552208\|RGD:8554334
Molecular Function	GO:0046982	protein heterodimerization activity	Gabbr1	IPI	UniProtKB:O75899	Rat	PMID:15304491\|RGD:12793050
Cellular Component	GO:0030673	axolemma	Gabbr1	IDA		Rat	PMID:17924569\|RGD:2315465
Cellular Component	GO:0005737	cytoplasm	Gabbr1	IDA		Mouse	PMID:15013631
Cellular Component	GO:0043198	dendritic shaft	Gabbr1	IDA		Rat	PMID:17241134\|RGD:2315460
Cellular Component	GO:0043197	dendritic spine	Gabbr1	IDA		Rat	PMID:16983643\|RGD:2315473
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Gabbr1	IDA		Rat	PMID:17924569\|RGD:2315465
Cellular Component	GO:0005615	extracellular space	Gabbr1	IDA		Rat	PMID:18765663\|RGD:7241136
Cellular Component	GO:1902712	G protein-coupled GABA receptor complex	GABBR1	IPI		Human	PMID:24305054
Cellular Component	GO:0038037	G protein-coupled receptor dimeric complex	Gabbr1	IDA		Mouse	PMID:20400944
Cellular Component	GO:0038039	G protein-coupled receptor heterodimeric complex	GABBR1	IPI	UniProtKB:O75899	Human	PMID:9872316
Cellular Component	GO:1902710	GABA receptor complex	Gabbr1	IDA		Rat	PMID:15304491\|RGD:12793050
Cellular Component	GO:0098982	GABA-ergic synapse	Gabbr1	IDA		Mouse	PMID:11498050
Cellular Component	GO:0098982	GABA-ergic synapse	Gabbr1	IMP		Mouse	PMID:11498050
Cellular Component	GO:0098982	GABA-ergic synapse	Gabbr1	EXP		Mouse	PMID:11498050
Cellular Component	GO:0098982	GABA-ergic synapse	Gabbr1	IDA		Rat	PMID:14657159\|RGD:13702400
Cellular Component	GO:0098978	glutamatergic synapse	Gabbr1	IDA		Rat	PMID:14657159\|RGD:13702400
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Gabbr1	IDA		Rat	PMID:17241134\|RGD:2315460
Cellular Component	GO:0016020	membrane	Gabbr1	IDA		Mouse	PMID:20400944
Cellular Component	GO:0045121	membrane raft	Gabbr1	IDA		Rat	PMID:19054408\|RGD:2315437
Cellular Component	GO:0031966	mitochondrial membrane	Gabbr1	IDA		Rat	PMID:17924569\|RGD:2315465
Cellular Component	GO:0043005	neuron projection	Gabbr1	IDA		Rat	PMID:17241134\|RGD:2315460
Cellular Component	GO:0043025	neuronal cell body	Gabbr1	IDA		Rat	PMID:17241134\|RGD:2315460
Cellular Component	GO:0005886	plasma membrane	GABBR1	IDA		Human	PMID:9872316
Cellular Component	GO:0005886	plasma membrane	Gabbr1	IDA		Rat	PMID:15304491\|RGD:12793050
Cellular Component	GO:0045211	postsynaptic membrane	Gabbr1	IDA		Mouse	PMID:20400944
Cellular Component	GO:0045211	postsynaptic membrane	Gabbr1	IDA		Rat	PMID:14657159\|RGD:13702400
Cellular Component	GO:0098793	presynapse	Gabbr1	IDA		Mouse	MGI:MGI:5816444\|PMID:21144999
Cellular Component	GO:0042734	presynaptic membrane	Gabbr1	IDA		Mouse	PMID:20400944
Cellular Component	GO:0042734	presynaptic membrane	Gabbr1	IDA		Rat	PMID:14657159\|RGD:13702400
Cellular Component	GO:0042734	presynaptic membrane	Gabbr1	IDA		Rat	PMID:17924569\|RGD:2315465
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Gabbr1	IDA		Mouse	PMID:11498050
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Gabbr1	IMP		Mouse	PMID:11498050
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Gabbr1	EXP		Mouse	PMID:11498050
Cellular Component	GO:0097060	synaptic membrane	Gabbr1	IDA		Rat	PMID:15304491\|RGD:12793050
Cellular Component	GO:0008021	synaptic vesicle	Gabbr1	IDA		Rat	PMID:17924569\|RGD:2315465
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GABBR1	IDA		Human	PMID:10328880
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GABBR1	IDA		Human	PMID:987231
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Gabbr1	IDA		Rat	PMID:9069281\|RGD:632819
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Gabbr1	IDA		Rat	PMID:15147298\|RGD:2315493
Biological Process	GO:0035095	behavioral response to nicotine	gabbr1b	IMP	ZFIN:ZDB-GENO-080603-2	Zfish	PMID:19858493
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABBR1	IDA		Human	PMID:987231
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABBR1	IDA		Human	PMID:9872316
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Gabbr1	IDA		Mouse	PMID:20400944
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Gabbr1	IDA		Rat	PMID:15147298\|RGD:2315493
Biological Process	GO:0007194	negative regulation of adenylate cyclase activity	Gabbr1	IMP		Rat	PMID:15147298\|RGD:2315493
Biological Process	GO:0008285	negative regulation of cell population proliferation	Gabbr1	IMP		Rat	PMID:15147298\|RGD:2315493
Biological Process	GO:0033602	negative regulation of dopamine secretion	Gabbr1	IDA		Rat	PMID:12872287\|RGD:2315496
Biological Process	GO:0032811	negative regulation of epinephrine secretion	Gabbr1	IMP		Rat	PMID:14568556\|RGD:2315495
Biological Process	GO:0014053	negative regulation of gamma-aminobutyric acid secretion	Gabbr1	IMP		Rat	PMID:14654095\|RGD:2315494
Biological Process	GO:0050805	negative regulation of synaptic transmission	Gabbr1	IDA		Rat	PMID:12604336\|RGD:2315497
Biological Process	GO:0150099	neuron-glial cell signaling	Gabbr1	IGI	UniProtKB:O88871	Rat	PMID:10196584\|RGD:14397583
Biological Process	GO:0001649	osteoblast differentiation	Gabbr1	IMP		Rat	PMID:12054677\|RGD:625463
Biological Process	GO:0014049	positive regulation of glutamate secretion	Gabbr1	IMP		Rat	PMID:18765663\|RGD:7241136
Biological Process	GO:0060124	positive regulation of growth hormone secretion	Gabbr1	IMP		Rat	PMID:12218349\|RGD:2315498
Biological Process	GO:0014048	regulation of glutamate secretion	Gabbr1	IDA		Rat	PMID:15561437\|RGD:2315491
Biological Process	GO:0045471	response to ethanol	Gabbr1	IEP		Rat	PMID:16246313\|RGD:2315490
Biological Process	GO:0035094	response to nicotine	Gabbr1	IEP		Rat	PMID:12435490\|RGD:632820

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.