Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GABRA5
  • Mouse genes Gabra5
  • Rat genes Gabra5
  • Zfish genes gabra5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabra5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050811	GABA receptor binding	Gabra5	IPI	RGD:2649	Rat	PMID:17959749|RGD:6480233
Molecular Function	GO:0050811	GABA receptor binding	Gabra5	IPI	RGD:621732	Rat	PMID:17959749|RGD:6480233
Molecular Function	GO:0004890	GABA-A receptor activity	Gabra5	IDA		Rat	PMID:2153588|RGD:61593
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GABRA5	IDA		Human	PMID:17681556
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GABRA5	IMP		Human	PMID:17681556
Molecular Function	GO:0005515	protein binding	Gabra5	IPI	UniProtKB:Q5WQV5	Mouse	MGI:MGI:5508256|PMID:16467845
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra5	EXP		Rat	PMID:17951598|RGD:13792546
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra5	IDA		Rat	PMID:17951598|RGD:13792546
Cellular Component	GO:0044297	cell body	Gabra5	IDA		Mouse	PMID:9682826
Cellular Component	GO:0005829	cytosol	GABRA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Gabra5	IDA		Mouse	PMID:9682826
Cellular Component	GO:0030425	dendrite	Gabra5	IDA		Rat	PMID:15246695|RGD:1358392
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra5	IDA		Rat	PMID:16998906|RGD:13702183
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra5	EXP		Rat	PMID:17951598|RGD:13792546
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra5	IDA		Rat	PMID:17951598|RGD:13792546
Cellular Component	GO:0016020	membrane	Gabra5	IDA		Rat	PMID:17959749|RGD:6480233
Cellular Component	GO:0032809	neuronal cell body membrane	Gabra5	IDA		Rat	PMID:15246695|RGD:1358392
Cellular Component	GO:0005654	nucleoplasm	GABRA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GABRA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045211	postsynaptic membrane	Gabra5	IDA		Rat	PMID:16998906|RGD:13702183
Cellular Component	GO:0099634	postsynaptic specialization membrane	Gabra5	IDA		Rat	PMID:16998906|RGD:13702183
Cellular Component	GO:0042734	presynaptic membrane	Gabra5	IDA		Rat	PMID:16998906|RGD:13702183
Cellular Component	GO:0043235	receptor complex	Gabra5	IDA		Rat	PMID:17959749|RGD:6480233
Biological Process	GO:0008306	associative learning	Gabra5	IMP	MGI:MGI:2183170	Mouse	PMID:12084936
Biological Process	GO:0001662	behavioral fear response	Gabra5	IMP	MGI:MGI:2183170	Mouse	PMID:12084936
Biological Process	GO:0007420	brain development	Gabra5	IEP		Rat	PMID:15246695|RGD:1358392
Biological Process	GO:0007268	chemical synaptic transmission	Gabra5	IEP		Rat	PMID:15246695|RGD:1358392
Biological Process	GO:0007268	chemical synaptic transmission	Gabra5	IMP		Rat	PMID:2153588|RGD:61593
Biological Process	GO:0090102	cochlea development	Gabra5	IMP		Mouse	MGI:MGI:3664129|PMID:17021187
Biological Process	GO:0060119	inner ear receptor cell development	Gabra5	IMP		Mouse	MGI:MGI:3664129|PMID:17021187
Biological Process	GO:0060384	innervation	Gabra5	IMP		Mouse	MGI:MGI:3664129|PMID:17021187
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Gabra5	IMP		Mouse	MGI:MGI:3664129|PMID:17021187
Biological Process	GO:0048666	neuron development	Gabra5	IMP		Mouse	MGI:MGI:3664129|PMID:17021187
Biological Process	GO:0043523	regulation of neuron apoptotic process	Gabra5	IMP		Mouse	MGI:MGI:3664129|PMID:17021187
Biological Process	GO:0007605	sensory perception of sound	Gabra5	IMP		Mouse	MGI:MGI:3664129|PMID:17021187

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern