Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gabrb3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GABRB3
- Mouse genes Gabrb3
- Rat genes Gabrb3
- Zfish genes gabrb3
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabrb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035612	AP-2 adaptor complex binding	Gabrb3	IPI	RGD:620135	Rat	PMID:16192353\|RGD:1601273
Molecular Function	GO:0005254	chloride channel activity	Gabrb3	IDA		Rat	PMID:12356876\|RGD:727440
Molecular Function	GO:0004890	GABA-A receptor activity	GABRB3	IMP		Human	PMID:22303015
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrb3	IMP		Mouse	MGI:MGI:87150\|PMID:9108119
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrb3	IDA		Rat	PMID:12356876\|RGD:727440
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrb3	IDA		Rat	PMID:15152020\|RGD:1358699
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrb3	IDA		Rat	PMID:2548852\|RGD:728451
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	GABRB3	IMP		Human	PMID:22303015
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	GABRB3	IMP		Human	PMID:26950270
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	GABRB3	IDA		Human	PMID:9039914
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	Gabrb3	IMP		Mouse	MGI:MGI:87150\|PMID:9108119
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	Gabrb3	IDA		Mouse	MGI:MGI:6208009\|PMID:27129275
Molecular Function	GO:0042802	identical protein binding	GABRB3	IPI	UniProtKB:P28472	Human	PMID:16537435
Molecular Function	GO:0042802	identical protein binding	GABRB3	IPI	UniProtKB:P28472	Human	PMID:24909990
Molecular Function	GO:0005216	monoatomic ion channel activity	Gabrb3	IDA		Mouse	PMID:12183328
Molecular Function	GO:0005515	protein binding	Gabrb3	IPI	UniProtKB:Q5U4E0	Mouse	MGI:MGI:6104059\|PMID:28978485
Molecular Function	GO:0005515	protein binding	Gabrb3	IPI	RGD:69194	Rat	PMID:12812758\|RGD:1601270
Molecular Function	GO:0005515	protein binding	Gabrb3	IPI	UniProtKB:Q7TSU1	Rat	PMID:15198677\|RGD:1304338
Molecular Function	GO:0005515	protein binding	Gabrb3	IPI	RGD:1359315	Rat	PMID:20417281\|RGD:8553984
Molecular Function	GO:0005515	protein binding	Gabrb3	IPI	UniProtKB:P18508,UniProtKB:P62813,UniProtKB:P63138,UniProtKB:Q62888,UniProtKB:Q7TSY2	Rat	PMID:28279354\|RGD:13800541
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabrb3	IDA		Mouse	PMID:12522165
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabrb3	IMP		Mouse	PMID:12522165
Cellular Component	GO:0009986	cell surface	Gabrb3	IDA		Mouse	PMID:12183328
Cellular Component	GO:1902711	GABA-A receptor complex	GABRB3	IPI		Human	PMID:30602789
Cellular Component	GO:1902711	GABA-A receptor complex	GABRB3	IMP		Human	PMID:22303015
Cellular Component	GO:1902711	GABA-A receptor complex	GABRB3	IDA		Human	PMID:26950270
Cellular Component	GO:1902711	GABA-A receptor complex	GABRB3	IDA		Human	PMID:9039914
Cellular Component	GO:1902711	GABA-A receptor complex	Gabrb3	IMP		Mouse	MGI:MGI:87150\|PMID:9108119
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrb3	IMP		Mouse	PMID:12522165
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrb3	IDA		Mouse	PMID:12522165
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrb3	IDA		Rat	PMID:21073549\|RGD:13702464
Cellular Component	GO:0060077	inhibitory synapse	Gabrb3	IDA		Rat	PMID:20417281\|RGD:8553984
Cellular Component	GO:0005886	plasma membrane	GABRB3	IMP		Human	PMID:22303015
Cellular Component	GO:0005886	plasma membrane	GABRB3	IDA		Human	PMID:26950270
Cellular Component	GO:0005886	plasma membrane	Gabrb3	IDA		Rat	PMID:15474980\|RGD:1601272
Cellular Component	GO:0005886	plasma membrane	Gabrb3	IDA		Rat	PMID:20417281\|RGD:8553984
Cellular Component	GO:0045211	postsynaptic membrane	Gabrb3	IDA		Rat	PMID:21073549\|RGD:13702464
Cellular Component	GO:0099634	postsynaptic specialization membrane	Gabrb3	IDA		Rat	PMID:21073549\|RGD:13702464
Cellular Component	GO:0043195	terminal bouton	Gabrb3	IDA		Rat	PMID:12812758\|RGD:1601270
Biological Process	GO:0007420	brain development	Gabrb3	IMP		Mouse	PMID:16168624
Biological Process	GO:0071420	cellular response to histamine	GABRB3	IDA		Human	PMID:18281286
Biological Process	GO:0071294	cellular response to zinc ion	Gabrb3	IDA		Mouse	PMID:12183328
Biological Process	GO:0021549	cerebellum development	Gabrb3	IMP		Mouse	PMID:17983671
Biological Process	GO:0007268	chemical synaptic transmission	Gabrb3	IMP		Mouse	MGI:MGI:3608285\|PMID:12522165
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Gabrb3	IMP		Mouse	MGI:MGI:3608285\|PMID:12522165
Biological Process	GO:1902476	chloride transmembrane transport	GABRB3	IMP		Human	PMID:22303015
Biological Process	GO:1902476	chloride transmembrane transport	GABRB3	IDA		Human	PMID:30602789
Biological Process	GO:1902476	chloride transmembrane transport	GABRB3	IDA		Human	PMID:9039914
Biological Process	GO:1902476	chloride transmembrane transport	Gabrb3	IMP		Mouse	MGI:MGI:87150\|PMID:9108119
Biological Process	GO:0042747	circadian sleep/wake cycle, REM sleep	Gabrb3	IMP		Mouse	PMID:12419540
Biological Process	GO:0090102	cochlea development	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:0035640	exploration behavior	Gabrb3	IMP		Mouse	PMID:17983671
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABRB3	IMP		Human	PMID:26950270
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABRB3	IDA		Human	PMID:30602789
Biological Process	GO:0060022	hard palate development	Gabrb3	IMP		Mouse	PMID:8389469
Biological Process	GO:0060022	hard palate development	Gabrb3	IDA		Mouse	PMID:12606284
Biological Process	GO:0060022	hard palate development	Gabrb3	IMP		Mouse	PMID:8146195
Biological Process	GO:0060022	hard palate development	Gabrb3	IMP		Mouse	PMID:7581464
Biological Process	GO:0060022	hard palate development	Gabrb3	IDA		Mouse	PMID:7581464
Biological Process	GO:0060080	inhibitory postsynaptic potential	Gabrb3	IMP		Mouse	MGI:MGI:5619469\|PMID:19846622
Biological Process	GO:1904862	inhibitory synapse assembly	GABRB3	IDA		Human	PMID:25489750
Biological Process	GO:1904862	inhibitory synapse assembly	Gabrb3	IDA		Mouse	MGI:MGI:6208009\|PMID:27129275
Biological Process	GO:0060119	inner ear receptor cell development	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:0060384	innervation	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:0007612	learning	Gabrb3	IMP		Mouse	PMID:9763493
Biological Process	GO:0007613	memory	Gabrb3	IMP		Mouse	PMID:9763493
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Gabrb3	IMP		Mouse	MGI:MGI:3608285\|PMID:12522165
Biological Process	GO:0061744	motor behavior	Gabrb3	IMP		Mouse	PMID:16168624
Biological Process	GO:0061744	motor behavior	Gabrb3	IMP		Mouse	PMID:9763493
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:1901215	negative regulation of neuron death	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:0007399	nervous system development	Gabrb3	IMP		Mouse	PMID:9763493
Biological Process	GO:0048666	neuron development	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:0043523	regulation of neuron apoptotic process	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Gabrb3	IMP		Mouse	MGI:MGI:3608285\|PMID:12522165
Biological Process	GO:0019098	reproductive behavior	Gabrb3	IMP		Mouse	PMID:17927825
Biological Process	GO:0072347	response to anesthetic	Gabrb3	IMP		Mouse	PMID:17319964
Biological Process	GO:0072347	response to anesthetic	Gabrb3	IMP		Mouse	PMID:17927825
Biological Process	GO:0072347	response to anesthetic	Gabrb3	IMP		Mouse	PMID:16871063
Biological Process	GO:0009410	response to xenobiotic stimulus	Gabrb3	IMP		Mouse	PMID:16168624
Biological Process	GO:0060021	roof of mouth development	Gabrb3	IMP		Mouse	MGI:MGI:87150\|PMID:9108119
Biological Process	GO:0007605	sensory perception of sound	Gabrb3	IMP		Mouse	MGI:MGI:3664129\|PMID:17021187
Biological Process	GO:0035176	social behavior	Gabrb3	IMP		Mouse	PMID:17983671
Biological Process	GO:0051932	synaptic transmission, GABAergic	Gabrb3	IDA		Rat	PMID:12356876\|RGD:727440

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.