Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GABRG2
  • Mouse genes Gabrg2
  • Rat genes Gabrg2
  • Zfish genes gabrg2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabrg2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	Gabrg2	IMP		Mouse	MGI:MGI:5574301|PMID:18281286
Molecular Function	GO:0005254	chloride channel activity	Gabrg2	IDA		Rat	PMID:2561970|RGD:61596
Molecular Function	GO:0016917	GABA receptor activity	Gabrg2	IDA		Rat	PMID:12930820|RGD:8554754
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrg2	IMP		Mouse	MGI:MGI:5574301|PMID:18281286
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrg2	IDA		Mouse	PMID:12574411
Molecular Function	GO:0004890	GABA-A receptor activity	Gabrg2	IDA		Rat	PMID:2561970|RGD:61596
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	GABRG2	IDA		Human	PMID:23909897
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	Gabrg2	IDA		Mouse	MGI:MGI:6208009|PMID:27129275
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	gabrg2	IDA		Zfish	PMID:30580138
Molecular Function	GO:0005515	protein binding	GABRG2	IPI	UniProtKB:P51513	Human	PMID:27733149
Molecular Function	GO:0005515	protein binding	GABRG2	IPI	UniProtKB:Q5U4E0	Human	PMID:28978485
Molecular Function	GO:0005515	protein binding	GABRG2	IPI	UniProtKB:O95166	Human	PMID:9892355
Molecular Function	GO:0005515	protein binding	GABRG2	IPI	UniProtKB:Q9H0R8	Human	PMID:9892355
Molecular Function	GO:0005515	protein binding	Gabrg2	IPI	UniProtKB:Q5U4E0	Mouse	MGI:MGI:6201911|PMID:29742426
Molecular Function	GO:0005515	protein binding	Gabrg2	IPI	PR:P63328	Mouse	PMID:12574411
Molecular Function	GO:0005515	protein binding	Gabrg2	IPI	RGD:61900	Rat	PMID:12091434|RGD:8548605
Molecular Function	GO:0005515	protein binding	Gabrg2	IPI	UniProtKB:P62813,UniProtKB:P63079,UniProtKB:P63138,UniProtKB:Q62888,UniProtKB:Q7TSY2	Rat	PMID:28279354|RGD:13800541
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabrg2	IDA		Mouse	PMID:15659595
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabrg2	IMP		Mouse	PMID:15659595
Cellular Component	GO:0030424	axon	Gabrg2	IDA		Mouse	PMID:9682826
Cellular Component	GO:0005737	cytoplasm	Gabrg2	IDA		Rat	PMID:11161482|RGD:625528
Cellular Component	GO:0032590	dendrite membrane	Gabrg2	IDA		Rat	PMID:15620359|RGD:8553937
Cellular Component	GO:1902710	GABA receptor complex	Gabrg2	IDA		Rat	PMID:12930820|RGD:8554754
Cellular Component	GO:1902711	GABA-A receptor complex	GABRG2	IPI		Human	PMID:29950725
Cellular Component	GO:1902711	GABA-A receptor complex	GABRG2	IPI		Human	PMID:30602789
Cellular Component	GO:1902711	GABA-A receptor complex	Gabrg2	IMP		Mouse	MGI:MGI:5574301|PMID:18281286
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrg2	IMP		Mouse	PMID:15659595
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrg2	IDA		Mouse	PMID:15659595
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrg2	IDA		Rat	PMID:9014159|RGD:13702271
Cellular Component	GO:0098982	GABA-ergic synapse	Gabrg2	IDA		Rat	PMID:9464994|RGD:13702323
Cellular Component	GO:0098978	glutamatergic synapse	Gabrg2	IDA		Rat	PMID:9464994|RGD:13702323
Cellular Component	GO:0060077	inhibitory synapse	Gabrg2	IDA		Rat	PMID:20417281|RGD:8553984
Cellular Component	GO:0005886	plasma membrane	Gabrg2	IMP		Mouse	MGI:MGI:5574301|PMID:18281286
Cellular Component	GO:0099634	postsynaptic specialization membrane	Gabrg2	IDA		Rat	PMID:9014159|RGD:13702271
Cellular Component	GO:0099634	postsynaptic specialization membrane	Gabrg2	IDA		Rat	PMID:9464994|RGD:13702323
Biological Process	GO:0030534	adult behavior	Gabrg2	IMP	MGI:MGI:3579440	Mouse	PMID:15850489
Biological Process	GO:0071420	cellular response to histamine	Gabrg2	IDA		Mouse	MGI:MGI:5574301|PMID:18281286
Biological Process	GO:0007268	chemical synaptic transmission	Gabrg2	IDA		Mouse	MGI:MGI:6201897|PMID:15659595
Biological Process	GO:0007268	chemical synaptic transmission	Gabrg2	IDA		Mouse	PMID:12574411
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Gabrg2	IDA		Mouse	MGI:MGI:6201897|PMID:15659595
Biological Process	GO:1902476	chloride transmembrane transport	GABRG2	IDA		Human	PMID:29950725
Biological Process	GO:1902476	chloride transmembrane transport	GABRG2	IDA		Human	PMID:30602789
Biological Process	GO:1902476	chloride transmembrane transport	Gabrg2	IMP		Mouse	MGI:MGI:5574301|PMID:18281286
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABRG2	IDA		Human	PMID:29950725
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABRG2	IDA		Human	PMID:30602789
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Gabrg2	IDA		Mouse	PMID:12574411
Biological Process	GO:1904862	inhibitory synapse assembly	GABRG2	IDA		Human	PMID:23909897
Biological Process	GO:1904862	inhibitory synapse assembly	GABRG2	IDA		Human	PMID:25489750
Biological Process	GO:1904862	inhibitory synapse assembly	Gabrg2	IDA		Mouse	MGI:MGI:6208009|PMID:27129275
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Gabrg2	IDA		Mouse	MGI:MGI:6201897|PMID:15659595
Biological Process	GO:0009791	post-embryonic development	Gabrg2	IMP	MGI:MGI:3582967	Mouse	PMID:15850489
Biological Process	GO:0070208	protein heterotrimerization	gabrg2	IDA		Zfish	PMID:30580138
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Gabrg2	IDA		Mouse	MGI:MGI:6201897|PMID:15659595
Biological Process	GO:0051932	synaptic transmission, GABAergic	Gabrg2	IDA		Rat	PMID:12930820|RGD:8554754

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern