Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GADD45B
  • Mouse genes Gadd45b
  • Rat genes Gadd45b
  • Zfish genes gadd45ba,gadd45bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gadd45b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GADD45B	IPI	UniProtKB:Q9Y6R4	Human	PMID:12052864
Molecular Function	GO:0005515	protein binding	GADD45B	IPI	UniProtKB:Q9Y6R4	Human	PMID:16256071
Molecular Function	GO:0005515	protein binding	GADD45B	IPI	UniProtKB:O14733	Human	PMID:25314077
Molecular Function	GO:0005515	protein binding	GADD45B	IPI	UniProtKB:Q5JVL4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GADD45B	IPI	UniProtKB:Q92600-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gadd45b	IPI	UniProtKB:Q8TAE8	Mouse	MGI:MGI:3843441|PMID:12716909
Molecular Function	GO:0005515	protein binding	Gadd45b	IPI	PR:P24860	Mouse	PMID:12124778
Cellular Component	GO:0005737	cytoplasm	GADD45B	IDA		Human	PMID:9827804
Cellular Component	GO:0005634	nucleus	GADD45B	IDA		Human	PMID:9827804
Biological Process	GO:0006469	negative regulation of protein kinase activity	Gadd45b	IDA		Mouse	PMID:12124778
Biological Process	GO:0043065	positive regulation of apoptotic process	GADD45B	IDA		Human	PMID:9827804
Biological Process	GO:0046330	positive regulation of JNK cascade	GADD45B	IDA		Human	PMID:9827804
Biological Process	GO:0043410	positive regulation of MAPK cascade	Gadd45b	IDA		Mouse	PMID:12213961
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	GADD45B	IDA		Human	PMID:9827804
Biological Process	GO:0051726	regulation of cell cycle	Gadd45b	IDA		Mouse	PMID:12124778
Biological Process	GO:1904633	regulation of podocyte apoptotic process	gadd45ba	IMP	ZFIN:ZDB-GENO-160601-6	Zfish	PMID:30022148
Biological Process	GO:0046686	response to cadmium ion	gadd45ba	IEP		Zfish	PMID:16799861
Biological Process	GO:0051597	response to methylmercury	gadd45ba	IDA		Zfish	PMID:15984772
Biological Process	GO:0001756	somitogenesis	gadd45ba	IGI	ZFIN:ZDB-MRPHLNO-050223-1,ZFIN:ZDB-MRPHLNO-050223-2	Zfish	PMID:15623554
Biological Process	GO:0001756	somitogenesis	gadd45ba	IMP		Zfish	PMID:15623554
Biological Process	GO:0001756	somitogenesis	gadd45bb	IMP		Zfish	PMID:15623554
Biological Process	GO:0001756	somitogenesis	gadd45bb	IGI	ZFIN:ZDB-MRPHLNO-050223-1,ZFIN:ZDB-MRPHLNO-050223-2	Zfish	PMID:15623554

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern