Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GAL
  • Mouse genes Gal
  • Rat genes Gal
  • Zfish genes gal
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gal

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004966	galanin receptor activity	GAL	IMP		Human	PMID:25691535
Molecular Function	GO:0005184	neuropeptide hormone activity	GAL	IDA		Human	PMID:24517231
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:O43603	Human	PMID:25691535
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:P47211	Human	PMID:25691535
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:Q12797-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:P23560-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:P31749	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:P35520	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAL	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Molecular Function	GO:0031764	type 1 galanin receptor binding	GAL	IDA		Human	PMID:24517231
Molecular Function	GO:0031765	type 2 galanin receptor binding	GAL	IDA		Human	PMID:24517231
Molecular Function	GO:0031766	type 3 galanin receptor binding	GAL	IDA		Human	PMID:24517231
Cellular Component	GO:0005737	cytoplasm	Gal	IDA		Rat	PMID:9487992|RGD:1624343
Cellular Component	GO:0005615	extracellular space	GAL	IDA		Human	PMID:9402244
Cellular Component	GO:0005794	Golgi apparatus	Gal	IDA		Rat	PMID:9487992|RGD:1624343
Cellular Component	GO:0043025	neuronal cell body	GAL	IDA		Human	PMID:23415787
Cellular Component	GO:0043025	neuronal cell body	gal	IDA		Zfish	PMID:27315774|ZFIN:ZDB-PUB-160619-8
Cellular Component	GO:0030141	secretory granule	Gal	IDA		Rat	PMID:1711463|RGD:1624342
Biological Process	GO:0019933	cAMP-mediated signaling	GAL	IDA		Human	PMID:17982695
Biological Process	GO:0007631	feeding behavior	Gal	IDA		Rat	PMID:9794487|RGD:1624337
Biological Process	GO:0006954	inflammatory response	Gal	IDA		Rat	PMID:14760801|RGD:1358702
Biological Process	GO:0008285	negative regulation of cell population proliferation	Gal	IDA		Rat	PMID:12119556|RGD:728693
Biological Process	GO:0050672	negative regulation of lymphocyte proliferation	Gal	IDA		Rat	PMID:12119556|RGD:728693
Biological Process	GO:0007399	nervous system development	Gal	IMP	MGI:MGI:2183172	Mouse	PMID:12533601
Biological Process	GO:0007218	neuropeptide signaling pathway	Gal	IMP	MGI:MGI:2183172	Mouse	PMID:12533601
Biological Process	GO:0043065	positive regulation of apoptotic process	Gal	IDA		Rat	PMID:12119556|RGD:728693
Biological Process	GO:0051464	positive regulation of cortisol secretion	GAL	IDA		Human	PMID:17982695
Biological Process	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity	GAL	IDA		Human	PMID:24602615
Biological Process	GO:0051795	positive regulation of timing of catagen	GAL	IDA		Human	PMID:22329353
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GAL	IDA		Human	PMID:24517231
Biological Process	GO:0010737	protein kinase A signaling	GAL	IDA		Human	PMID:17982695
Biological Process	GO:0031943	regulation of glucocorticoid metabolic process	Gal	IMP		Rat	PMID:17273801|RGD:1624340
Biological Process	GO:0043627	response to estrogen	Gal	IEP		Rat	PMID:1711463|RGD:1624342
Biological Process	GO:0035902	response to immobilization stress	Gal	IEP		Rat	PMID:10350643|RGD:1624336
Biological Process	GO:0032868	response to insulin	Gal	IEP		Rat	PMID:8738309|RGD:1624338
Biological Process	GO:0009416	response to light stimulus	gal	IGI	ZFIN:ZDB-GENE-100726-1	Zfish	PMID:28648499
Biological Process	GO:0009410	response to xenobiotic stimulus	Gal	IEP		Rat	PMID:15526991|RGD:1624332
Biological Process	GO:0030431	sleep	gal	IGI	ZFIN:ZDB-GENE-100726-1	Zfish	PMID:28648499

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern