Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GAP43
  • Mouse genes Gap43
  • Rat genes Gap43
  • Zfish genes gap43
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gap43

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035727	lysophosphatidic acid binding	Gap43	IDA		Rat	PMID:17295609|RGD:9835427
Molecular Function	GO:1901981	phosphatidylinositol phosphate binding	Gap43	IDA		Rat	PMID:17295609|RGD:9835427
Molecular Function	GO:0001786	phosphatidylserine binding	Gap43	IDA		Rat	PMID:1826685|RGD:9835424
Molecular Function	GO:0005515	protein binding	GAP43	IPI	UniProtKB:P05067-8	Human	PMID:30664241
Molecular Function	GO:0005515	protein binding	GAP43	IPI	UniProtKB:P21917	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAP43	IPI	UniProtKB:Q05655	Human	PMID:9139733
Molecular Function	GO:0005515	protein binding	Gap43	IPI	UniProtKB:Q5XIE8	Rat	PMID:29476059|RGD:42721991
Cellular Component	GO:0030424	axon	Gap43	IDA		Mouse	PMID:10850491
Cellular Component	GO:0030424	axon	Gap43	IDA		Mouse	PMID:15071120
Cellular Component	GO:0030424	axon	Gap43	IDA		Mouse	PMID:10482234
Cellular Component	GO:0071944	cell periphery	Gap43	IDA		Mouse	PMID:21752992
Cellular Component	GO:0005737	cytoplasm	Gap43	IDA		Mouse	PMID:24582971
Cellular Component	GO:0005737	cytoplasm	Gap43	IDA		Rat	PMID:21912933|RGD:7205683
Cellular Component	GO:0031527	filopodium membrane	GAP43	IDA		Human	PMID:14978216
Cellular Component	GO:0098982	GABA-ergic synapse	Gap43	IDA		Rat	PMID:25755278|RGD:13702431
Cellular Component	GO:0098982	GABA-ergic synapse	Gap43	IMP		Rat	PMID:25755278|RGD:13702431
Cellular Component	GO:0005886	plasma membrane	GAP43	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GAP43	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005886	plasma membrane	Gap43	IDA		Mouse	PMID:16892058
Cellular Component	GO:0014069	postsynaptic density	Gap43	IDA		Mouse	PMID:17114649
Cellular Component	GO:0098793	presynapse	Gap43	IDA		Rat	PMID:16203100|RGD:155230715
Biological Process	GO:0048708	astrocyte differentiation	Gap43	IMP	MGI:MGI:2180341	Mouse	PMID:15234344
Biological Process	GO:0016198	axon choice point recognition	Gap43	IMP	MGI:MGI:2448337	Mouse	PMID:7859286
Biological Process	GO:0007411	axon guidance	Gap43	IMP	MGI:MGI:2448337	Mouse	PMID:10662636
Biological Process	GO:0031103	axon regeneration	gap43	IMP	ZFIN:ZDB-MRPHLNO-150604-3	Zfish	PMID:25751153
Biological Process	GO:0045165	cell fate commitment	Gap43	IMP		Mouse	PMID:15234344
Biological Process	GO:0007399	nervous system development	Gap43	IEP		Rat	PMID:2437653|RGD:728446
Biological Process	GO:0060019	radial glial cell differentiation	Gap43	IMP	MGI:MGI:2180341	Mouse	PMID:15234344
Biological Process	GO:0051489	regulation of filopodium assembly	GAP43	IDA		Human	PMID:14978216
Biological Process	GO:0099150	regulation of postsynaptic specialization assembly	Gap43	IDA		Rat	PMID:25755278|RGD:13702431
Biological Process	GO:0099150	regulation of postsynaptic specialization assembly	Gap43	IMP		Rat	PMID:25755278|RGD:13702431
Biological Process	GO:0042246	tissue regeneration	Gap43	IEP		Rat	PMID:12597125|RGD:728776
Biological Process	GO:0042246	tissue regeneration	gap43	IEP		Zfish	PMID:16205622

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern