Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GAPDH
  • Mouse genes Gapdh-ps15
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gapdh-ps15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019828	aspartic-type endopeptidase inhibitor activity	GAPDH	IDA		Human	PMID:22832495
Molecular Function	GO:0097718	disordered domain specific binding	GAPDH	IPI	UniProtKB:P21758	Human	PMID:11785981
Molecular Function	GO:0042802	identical protein binding	GAPDH	IPI	UniProtKB:P04406	Human	PMID:20392205
Molecular Function	GO:0042802	identical protein binding	GAPDH	IPI	UniProtKB:P04406	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P41743	Human	PMID:11724794
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P23381	Human	PMID:15628863
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P15927	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:16799092
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:O95292	Human	PMID:17540579
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00558	Human	PMID:20392205
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P12004	Human	PMID:20849852
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q12933	Human	PMID:23332158
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P48147	Human	PMID:23348613
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P21754	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q05996	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q12836	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P05109	Human	PMID:25417112
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P35228	Human	PMID:25417112
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q13114	Human	PMID:27387501
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P42695	Human	PMID:29028794
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00441	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:O00471	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:O75344	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P06241	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P10599	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P35222	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q14194	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q6UY14-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q8NEA9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q8WUY3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q92993-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q96GZ6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9BPW9-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9UHX1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9UIJ7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GAPDH	IPI	UniProtKB:Q9UQM7	Human	PMID:32814053
Cellular Component	GO:0005737	cytoplasm	GAPDH	IDA		Human	PMID:11785981
Cellular Component	GO:0005737	cytoplasm	GAPDH	IDA		Human	PMID:24507776
Cellular Component	GO:0005829	cytosol	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	GAPDH	IDA		Human	PMID:24101517
Cellular Component	GO:0005829	cytosol	GAPDH	IDA		Human	PMID:28404743
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:12519789
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	GAPDH	HDA		Human	PMID:23533145
Cellular Component	GO:0097452	GAIT complex	GAPDH	IDA		Human	PMID:15479637
Cellular Component	GO:0097452	GAIT complex	GAPDH	IDA		Human	PMID:23071094
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005811	lipid droplet	GAPDH	IDA		Human	PMID:14741744
Cellular Component	GO:0016020	membrane	GAPDH	HDA		Human	PMID:19946888
Cellular Component	GO:0031965	nuclear membrane	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GAPDH	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	GAPDH	IDA		Human	PMID:28404743
Cellular Component	GO:0005886	plasma membrane	GAPDH	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990904	ribonucleoprotein complex	GAPDH	IDA		Human	PMID:15479637
Cellular Component	GO:0031982	vesicle	GAPDH	HDA		Human	PMID:19190083
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0071346	cellular response to type II interferon	GAPDH	IDA		Human	PMID:15479637
Biological Process	GO:0050832	defense response to fungus	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0051873	killing by host of symbiont cells	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0031640	killing of cells of another organism	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0010951	negative regulation of endopeptidase activity	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0017148	negative regulation of translation	GAPDH	IMP		Human	PMID:15479637
Biological Process	GO:0017148	negative regulation of translation	GAPDH	IDA		Human	PMID:23071094
Biological Process	GO:0001819	positive regulation of cytokine production	GAPDH	IDA		Human	PMID:22832495
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	GAPDH	IDA		Human	PMID:23332158
Biological Process	GO:0032481	positive regulation of type I interferon production	GAPDH	IDA		Human	PMID:27387501

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern