Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GAS1
  • Mouse genes Gas1
  • Rat genes Gas1
  • Zfish genes gas1a,gas1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gas1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GAS1	IPI	UniProtKB:P05067-4	Human	PMID:21357679
Molecular Function	GO:0005515	protein binding	Gas1	IPI	UniProtKB:Q62226	Mouse	MGI:MGI:4357747|PMID:19478089
Molecular Function	GO:0005515	protein binding	Gas1	IPI	UniProtKB:O35158|UniProtKB:Q32MD9|UniProtKB:Q6AZB0|UniProtKB:Q9BWV1	Mouse	MGI:MGI:5444826|PMID:21802063
Molecular Function	GO:0005515	protein binding	Gas1	IPI	PR:Q62226	Mouse	PMID:11572986
Molecular Function	GO:0005515	protein binding	Gas1	IPI	PR:Q62210	Mouse	PMID:11906213
Cellular Component	GO:0016020	membrane	Gas1	IDA		Mouse	PMID:11906213
Cellular Component	GO:0005886	plasma membrane	GAS1	IDA		Human	PMID:8127893
Cellular Component	GO:0005886	plasma membrane	Gas1	IDA		Mouse	PMID:10996315
Biological Process	GO:0006915	apoptotic process	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456442
Biological Process	GO:0007411	axon guidance	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504941
Biological Process	GO:0043010	camera-type eye development	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0045165	cell fate commitment	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504941
Biological Process	GO:0045165	cell fate commitment	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456441
Biological Process	GO:0045165	cell fate commitment	Gas1	IGI	MGI:MGI:98297	Mouse	PMID:17504941
Biological Process	GO:0008283	cell population proliferation	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456442
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	GAS1	IEP		Human	PMID:15070677
Biological Process	GO:0021587	cerebellum morphogenesis	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456442
Biological Process	GO:0048589	developmental growth	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456442
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504941
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Gas1	IGI	MGI:MGI:98297	Mouse	PMID:17504941
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504940
Biological Process	GO:0009953	dorsal/ventral pattern formation	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504940
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	Gas1	IGI	MGI:MGI:98297	Mouse	PMID:17525797
Biological Process	GO:0042733	embryonic digit morphogenesis	Gas1	IGI	MGI:MGI:98297	Mouse	PMID:17504941
Biological Process	GO:0042733	embryonic digit morphogenesis	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504940
Biological Process	GO:0042733	embryonic digit morphogenesis	Gas1	IGI	MGI:MGI:98297	Mouse	PMID:17504940
Biological Process	GO:0042733	embryonic digit morphogenesis	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504941
Biological Process	GO:0048598	embryonic morphogenesis	Gas1	IGI	MGI:MGI:1926387	Mouse	PMID:17504941
Biological Process	GO:0048598	embryonic morphogenesis	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504941
Biological Process	GO:0048706	embryonic skeletal system development	Gas1	IGI	MGI:MGI:98297	Mouse	PMID:17504941
Biological Process	GO:0048706	embryonic skeletal system development	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504941
Biological Process	GO:0048592	eye morphogenesis	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456441
Biological Process	GO:0042474	middle ear morphogenesis	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0043066	negative regulation of apoptotic process	Gas1	IDA		Mouse	MGI:MGI:5306314|PMID:15070677
Biological Process	GO:0043066	negative regulation of apoptotic process	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456442
Biological Process	GO:0030308	negative regulation of cell growth	Gas1	IDA		Mouse	MGI:MGI:5306329|PMID:10996316
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456441
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Gas1	IDA		Mouse	PMID:15070677
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	GAS1	IGI	UniProtKB:P04637	Human	PMID:11356029
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	GAS1	IDA		Human	PMID:8127893
Biological Process	GO:0010955	negative regulation of protein processing	GAS1	IMP		Human	PMID:21357679
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	Gas1	IDA		Mouse	PMID:11572986
Biological Process	GO:0042476	odontogenesis	Gas1	IMP		Mouse	MGI:MGI:3838072|PMID:19211681
Biological Process	GO:0042473	outer ear morphogenesis	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0008284	positive regulation of cell population proliferation	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:11456442
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Gas1	IDA		Mouse	PMID:17504940
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504940
Biological Process	GO:0012501	programmed cell death	Gas1	IDA		Mouse	PMID:11906213
Biological Process	GO:0060628	regulation of ER to Golgi vesicle-mediated transport	GAS1	IMP		Human	PMID:21357679
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Gas1	IMP		Mouse	MGI:MGI:4357747|PMID:19478089
Biological Process	GO:0060021	roof of mouth development	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0007224	smoothened signaling pathway	Gas1	IMP	MGI:MGI:2388397	Mouse	PMID:17525797
Biological Process	GO:0007224	smoothened signaling pathway	Gas1	IMP	MGI:MGI:3711070	Mouse	PMID:17504940

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern