Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gcgr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GCGR
- Mouse genes Gcgr
- Rat genes Gcgr
- Zfish genes gcgra,gcgrb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gcgr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004967	glucagon receptor activity	GCGR	IDA		Human	PMID:28514451
Molecular Function	GO:0004967	glucagon receptor activity	GCGR	IDA		Human	PMID:9287038
Molecular Function	GO:0004967	glucagon receptor activity	Gcgr	IDA		Mouse	MGI:MGI:2449992\|PMID:12552113
Molecular Function	GO:0004967	glucagon receptor activity	Gcgr	IMP	MGI:MGI:3505881	Mouse	PMID:30380405
Molecular Function	GO:0004967	glucagon receptor activity	Gcgr	IMP		Rat	PMID:15687107\|RGD:1625210
Molecular Function	GO:0004967	glucagon receptor activity	Gcgr	IDA		Rat	PMID:17010343\|RGD:2315004
Molecular Function	GO:0004967	glucagon receptor activity	Gcgr	IDA		Rat	PMID:8386505\|RGD:728550
Molecular Function	GO:0004967	glucagon receptor activity	Gcgr	IMP		Rat	PMID:8552628\|RGD:2315020
Molecular Function	GO:0004967	glucagon receptor activity	gcgra	IDA		Zfish	PMID:19793957
Molecular Function	GO:0005096	GTPase activator activity	Gcgr	IMP	MGI:MGI:3505881	Mouse	PMID:30380405
Molecular Function	GO:0017046	peptide hormone binding	Gcgr	IDA		Rat	PMID:15687107\|RGD:1625210
Molecular Function	GO:0017046	peptide hormone binding	Gcgr	IDA		Rat	PMID:17010343\|RGD:2315004
Molecular Function	GO:0017046	peptide hormone binding	Gcgr	IMP		Rat	PMID:8552628\|RGD:2315020
Molecular Function	GO:0017046	peptide hormone binding	gcgra	IPI	ZFIN:ZDB-GENE-040712-2	Zfish	PMID:26446275
Molecular Function	GO:0017046	peptide hormone binding	gcgra	IPI	ZFIN:ZDB-GENE-010219-1	Zfish	PMID:26446275
Molecular Function	GO:0017046	peptide hormone binding	gcgrb	IPI	ZFIN:ZDB-GENE-040712-2	Zfish	PMID:26446275
Molecular Function	GO:0017046	peptide hormone binding	gcgrb	IPI	ZFIN:ZDB-GENE-010219-1	Zfish	PMID:26446275
Molecular Function	GO:0017046	peptide hormone binding	gcgrb	IDA		Zfish	PMID:27930690
Molecular Function	GO:0017046	peptide hormone binding	gcgrb	IPI	ZFIN:ZDB-GENE-010219-1	Zfish	PMID:27930690
Molecular Function	GO:0017046	peptide hormone binding	gcgrb	IPI	ZFIN:ZDB-GENE-040712-2	Zfish	PMID:27930690
Cellular Component	GO:0005768	endosome	Gcgr	IDA		Rat	PMID:17010343\|RGD:2315004
Cellular Component	GO:0005886	plasma membrane	GCGR	IMP		Human	PMID:28514451
Cellular Component	GO:0005886	plasma membrane	GCGR	IDA		Human	PMID:9287038
Cellular Component	GO:0005886	plasma membrane	Gcgr	IDA		Mouse	PMID:30380405
Cellular Component	GO:0005886	plasma membrane	Gcgr	IDA		Rat	PMID:15687107\|RGD:1625210
Cellular Component	GO:0005886	plasma membrane	Gcgr	IDA		Rat	PMID:17010343\|RGD:2315004
Cellular Component	GO:0005886	plasma membrane	Gcgr	IDA		Rat	PMID:8552628\|RGD:2315020
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GCGR	IDA		Human	PMID:28514451
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Gcgr	IDA		Rat	PMID:15459251\|RGD:1625209
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GCGR	IMP		Human	PMID:9287038
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Gcgr	IDA		Mouse	MGI:MGI:2449992\|PMID:12552113
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Gcgr	IMP		Rat	PMID:8552628\|RGD:2315020
Biological Process	GO:0071377	cellular response to glucagon stimulus	GCGR	IDA		Human	PMID:9287038
Biological Process	GO:0071377	cellular response to glucagon stimulus	Gcgr	IDA		Mouse	MGI:MGI:2449992\|PMID:12552113
Biological Process	GO:0071377	cellular response to glucagon stimulus	Gcgr	IDA		Mouse	PMID:30380405
Biological Process	GO:0009267	cellular response to starvation	Gcgr	IMP		Mouse	MGI:MGI:5474727\|PMID:23209793
Biological Process	GO:0006887	exocytosis	Gcgr	IDA		Rat	PMID:15459251\|RGD:1625209
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gcgr	IMP		Rat	PMID:15687107\|RGD:1625210
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gcgr	IDA		Rat	PMID:17010343\|RGD:2315004
Biological Process	GO:0042593	glucose homeostasis	Gcgr	IMP		Mouse	MGI:MGI:2449992\|PMID:12552113
Biological Process	GO:0009755	hormone-mediated signaling pathway	Gcgr	IMP		Rat	PMID:15687107\|RGD:1625210
Biological Process	GO:0009755	hormone-mediated signaling pathway	Gcgr	IDA		Rat	PMID:17010343\|RGD:2315004
Biological Process	GO:0010628	positive regulation of gene expression	Gcgr	IMP		Mouse	MGI:MGI:5474727\|PMID:23209793
Biological Process	GO:0010906	regulation of glucose metabolic process	gcgra	IMP	ZFIN:ZDB-GENO-160413-7	Zfish	PMID:26446275
Biological Process	GO:0010906	regulation of glucose metabolic process	gcgra	IGI	ZFIN:ZDB-GENO-160413-9	Zfish	PMID:26446275
Biological Process	GO:0010906	regulation of glucose metabolic process	gcgrb	IMP	ZFIN:ZDB-GENO-160413-8	Zfish	PMID:26446275
Biological Process	GO:0010906	regulation of glucose metabolic process	gcgrb	IGI	ZFIN:ZDB-GENO-160413-9	Zfish	PMID:26446275
Biological Process	GO:0070873	regulation of glycogen metabolic process	Gcgr	IMP		Mouse	MGI:MGI:2449992\|PMID:12552113
Biological Process	GO:0042594	response to starvation	Gcgr	IMP		Mouse	MGI:MGI:3828901\|PMID:19046568

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.