Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GCHFR
  • Mouse genes Gchfr
  • Rat genes Gchfr
  • Zfish genes gchfr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gchfr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Gchfr	IDA		Rat	PMID:11818540|RGD:2298660
Molecular Function	GO:0019899	enzyme binding	Gchfr	IDA		Rat	PMID:8702680|RGD:728623
Molecular Function	GO:0004857	enzyme inhibitor activity	Gchfr	IDA		Rat	PMID:8702680|RGD:728623
Molecular Function	GO:0044549	GTP cyclohydrolase binding	Gchfr	IPI	RGD:61992	Rat	PMID:15448133|RGD:1601286
Molecular Function	GO:0044549	GTP cyclohydrolase binding	Gchfr	IDA		Rat	PMID:8702680|RGD:728623
Molecular Function	GO:0044549	GTP cyclohydrolase binding	Gchfr	IPI	RGD:61992	Rat	PMID:9685352|RGD:2298656
Molecular Function	GO:0030742	GTP-dependent protein binding	Gchfr	IPI	RGD:61992	Rat	PMID:9685352|RGD:2298656
Molecular Function	GO:0005515	protein binding	GCHFR	IPI	UniProtKB:P30793	Human	PMID:16696853
Molecular Function	GO:0005515	protein binding	GCHFR	IPI	UniProtKB:P30793	Human	PMID:9092499
Molecular Function	GO:0005515	protein binding	Gchfr	IPI	UniProtKB:P22288	Rat	PMID:11818540|RGD:2298660
Molecular Function	GO:0005515	protein binding	Gchfr	IPI	UniProtKB:P22288	Rat	PMID:15448133|RGD:1601286
Molecular Function	GO:0044877	protein-containing complex binding	Gchfr	IDA		Rat	PMID:11818540|RGD:2298660
Molecular Function	GO:0044877	protein-containing complex binding	Gchfr	IPI	RGD:61992	Rat	PMID:15448133|RGD:1601286
Molecular Function	GO:0044877	protein-containing complex binding	Gchfr	IDA		Rat	PMID:9685352|RGD:2298656
Cellular Component	GO:0005737	cytoplasm	GCHFR	IDA		Human	PMID:16778797
Cellular Component	GO:0030425	dendrite	GCHFR	IDA		Human	PMID:16778797
Cellular Component	GO:0042470	melanosome	GCHFR	IDA		Human	PMID:16778797
Cellular Component	GO:0031965	nuclear membrane	GCHFR	IDA		Human	PMID:16778797
Cellular Component	GO:0005654	nucleoplasm	GCHFR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GCHFR	IDA		Human	PMID:16778797
Cellular Component	GO:0032991	protein-containing complex	Gchfr	IDA		Rat	PMID:11818540|RGD:2298660
Cellular Component	GO:0032991	protein-containing complex	Gchfr	IDA		Rat	PMID:15448133|RGD:1601286
Cellular Component	GO:0032991	protein-containing complex	Gchfr	IDA		Rat	PMID:8702680|RGD:728623
Biological Process	GO:0043105	negative regulation of GTP cyclohydrolase I activity	Gchfr	IDA		Rat	PMID:8702680|RGD:728623
Biological Process	GO:0065003	protein-containing complex assembly	Gchfr	IDA		Rat	PMID:11818540|RGD:2298660
Biological Process	GO:0065003	protein-containing complex assembly	Gchfr	IDA		Rat	PMID:15448133|RGD:1601286
Biological Process	GO:0065003	protein-containing complex assembly	Gchfr	IDA		Rat	PMID:9685352|RGD:2298656

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern