Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GCM1
  • Mouse genes Gcm1
  • Rat genes Gcm1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gcm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Gcm1	IDA		Mouse	PMID:12297286
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GCM1	IDA		Human	PMID:15385555
Molecular Function	GO:0003700	DNA-binding transcription factor activity	GCM1	IDA		Human	PMID:15385555
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GCM1	IDA		Human	PMID:23867755
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GCM1	IDA		Human	PMID:27917469
Molecular Function	GO:0042826	histone deacetylase binding	GCM1	IPI	UniProtKB:Q9UQL6	Human	PMID:23867755
Molecular Function	GO:0005515	protein binding	GCM1	IPI	UniProtKB:Q9UKT8	Human	PMID:23651062
Molecular Function	GO:0005515	protein binding	GCM1	IPI	UniProtKB:P56524	Human	PMID:23867755
Molecular Function	GO:0005515	protein binding	GCM1	IPI	UniProtKB:P23771	Human	PMID:26899996
Molecular Function	GO:0005515	protein binding	GCM1	IPI	UniProtKB:O60479	Human	PMID:28515447
Molecular Function	GO:0005515	protein binding	Gcm1	IPI	PR:P45481	Mouse	PMID:21558372
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	GCM1	IDA		Human	PMID:15385555
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	GCM1	IDA		Human	PMID:28473536
Molecular Function	GO:0008270	zinc ion binding	Gcm1	IDA		Mouse	PMID:12297286
Cellular Component	GO:0005634	nucleus	GCM1	IDA		Human	PMID:23867755
Cellular Component	GO:0005634	nucleus	Gcm1	IDA		Mouse	PMID:14573516
Cellular Component	GO:0005667	transcription regulator complex	GCM1	IDA		Human	PMID:15385555
Biological Process	GO:0060018	astrocyte fate commitment	Gcm1	IDA		Mouse	PMID:14573516
Biological Process	GO:0060670	branching involved in labyrinthine layer morphogenesis	Gcm1	IMP	MGI:MGI:2183479	Mouse	PMID:10888880
Biological Process	GO:0060706	cell differentiation involved in embryonic placenta development	Gcm1	IMP	MGI:MGI:2183479	Mouse	PMID:10888880
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	GCM1	IDA		Human	PMID:27917469
Biological Process	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	Gcm1	IGI	MGI:MGI:97308	Mouse	PMID:21558372
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GCM1	IDA		Human	PMID:15385555
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Gcm1	IMP	MGI:MGI:2183479	Mouse	PMID:23610556
Biological Process	GO:0060800	regulation of cell differentiation involved in embryonic placenta development	GCM1	IMP		Human	PMID:19219068
Biological Process	GO:0006355	regulation of DNA-templated transcription	GCM1	IDA		Human	PMID:15385555
Biological Process	GO:0000768	syncytium formation by plasma membrane fusion	Gcm1	IGI	MGI:MGI:97308	Mouse	PMID:21558372
Biological Process	GO:0006366	transcription by RNA polymerase II	GCM1	IDA		Human	PMID:23867755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern