Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GGA3
  • Mouse genes Gga3
  • Rat genes Gga3
  • Zfish genes gga3a,gga3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gga3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P11717	Human	PMID:11387475
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:Q15276	Human	PMID:12505986
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:Q9UJY4	Human	PMID:14638859
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:Q9UJY5	Human	PMID:14638859
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P0CG47	Human	PMID:15039775
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:Q99816	Human	PMID:15039775
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P11717	Human	PMID:16977309
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:Q6VY07	Human	PMID:16977309
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P62330	Human	PMID:23143332
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P62330	Human	PMID:24056087
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P56817	Human	PMID:26053850
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P04629	Human	PMID:26446845
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:P18089	Human	PMID:26811329
Molecular Function	GO:0005515	protein binding	GGA3	IPI	UniProtKB:Q99816	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Gga3	IPI	UniProtKB:P35739	Rat	PMID:26446845|RGD:11554955
Molecular Function	GO:0044877	protein-containing complex binding	GGA3	IDA		Human	PMID:17116753
Molecular Function	GO:0031267	small GTPase binding	GGA3	IDA		Human	PMID:10749927
Molecular Function	GO:0043130	ubiquitin binding	GGA3	IDA		Human	PMID:17116753
Molecular Function	GO:0043130	ubiquitin binding	GGA3	IDA		Human	PMID:20484053
Cellular Component	GO:0005769	early endosome	Gga3	IDA		Rat	PMID:26446845|RGD:11554955
Cellular Component	GO:0005794	Golgi apparatus	GGA3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	GGA3	IDA		Human	PMID:17116753
Cellular Component	GO:0032991	protein-containing complex	GGA3	IDA		Human	PMID:17116753
Cellular Component	GO:0055037	recycling endosome	Gga3	IDA		Rat	PMID:26446845|RGD:11554955
Cellular Component	GO:0005802	trans-Golgi network	GGA3	IDA		Human	PMID:10749927
Biological Process	GO:0032456	endocytic recycling	Gga3	IDA		Rat	PMID:26446845|RGD:11554955
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	GGA3	IMP		Human	PMID:27901063
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	GGA3	IDA		Human	PMID:17553422
Biological Process	GO:0045732	positive regulation of protein catabolic process	Gga3	IGI	MGI:MGI:2146207	Mouse	PMID:22836275
Biological Process	GO:0030163	protein catabolic process	Gga3	IGI	MGI:MGI:2146207	Mouse	PMID:22836275
Biological Process	GO:0031648	protein destabilization	GGA3	IDA		Human	PMID:20484053
Biological Process	GO:0034394	protein localization to cell surface	GGA3	IMP		Human	PMID:27901063
Biological Process	GO:0061462	protein localization to lysosome	Gga3	IMP		Mouse	PMID:25592972
Biological Process	GO:0006622	protein targeting to lysosome	GGA3	IPI	UniProtKB:P46934	Human	PMID:17116753
Biological Process	GO:0031647	regulation of protein stability	GGA3	IDA		Human	PMID:17553422
Biological Process	GO:0031647	regulation of protein stability	GGA3	IDA		Human	PMID:20484053

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern