Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ghrh

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GHRH
- Mouse genes Ghrh
- Rat genes Ghrh
- Zfish genes ghrh
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ghrh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016608	growth hormone-releasing hormone activity	GHRH	IDA		Human	PMID:18329818
Molecular Function	GO:0016608	growth hormone-releasing hormone activity	GHRH	IDA		Human	PMID:8421089
Molecular Function	GO:0016608	growth hormone-releasing hormone activity	Ghrh	IDA		Rat	PMID:12446584\|RGD:628502
Molecular Function	GO:0016608	growth hormone-releasing hormone activity	ghrh	IDA		Zfish	PMID:17283332
Molecular Function	GO:0031770	growth hormone-releasing hormone receptor binding	GHRH	IPI	UniProtKB:Q02643	Human	PMID:1333056
Molecular Function	GO:0031770	growth hormone-releasing hormone receptor binding	GHRH	IPI	UniProtKB:Q02643	Human	PMID:7680413
Molecular Function	GO:0031770	growth hormone-releasing hormone receptor binding	Ghrh	IPI	UniProtKB:P32082	Mouse	MGI:MGI:3833824\|PMID:11773624
Molecular Function	GO:0005515	protein binding	Ghrh	IPI	PR:P32082	Mouse	PMID:10537133
Cellular Component	GO:0043679	axon terminus	Ghrh	IDA		Rat	PMID:6423368\|RGD:2289999
Cellular Component	GO:0005615	extracellular space	Ghrh	IDA		Mouse	PMID:7980597
Cellular Component	GO:0005615	extracellular space	Ghrh	IDA		Mouse	PMID:7867561
Cellular Component	GO:0005615	extracellular space	Ghrh	IDA		Mouse	PMID:7912976
Cellular Component	GO:0005615	extracellular space	Ghrh	IDA		Rat	PMID:1537276\|RGD:2289994
Cellular Component	GO:0043005	neuron projection	Ghrh	IDA		Rat	PMID:6423368\|RGD:2289999
Cellular Component	GO:0043204	perikaryon	Ghrh	IDA		Rat	PMID:6423368\|RGD:2289999
Cellular Component	GO:0043195	terminal bouton	Ghrh	IDA		Mouse	PMID:7694848
Biological Process	GO:0021984	adenohypophysis development	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:15985453
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GHRH	IDA		Human	PMID:3008329
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GHRH	IDA		Human	PMID:1333056
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GHRH	IDA		Human	PMID:7680413
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ghrh	IMP		Mouse	MGI:MGI:3833824\|PMID:11773624
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ghrh	IDA		Mouse	PMID:10537133
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ghrh	IGI	MGI:MGI:95710	Mouse	PMID:8395283
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ghrh	IGI	MGI:MGI:95710	Mouse	PMID:8391647
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ghrh	IGI	MGI:MGI:95710	Mouse	PMID:1334535
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Ghrh	IDA		Rat	PMID:12446584\|RGD:628502
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Ghrh	IDA		Rat	PMID:14664705\|RGD:1601331
Biological Process	GO:0071354	cellular response to interleukin-6	Ghrh	IEP		Rat	PMID:19239705\|RGD:5687170
Biological Process	GO:0042748	circadian sleep/wake cycle, non-REM sleep	Ghrh	IDA		Rat	PMID:17537840\|RGD:2289986
Biological Process	GO:0030252	growth hormone secretion	GHRH	IDA		Human	PMID:2857452
Biological Process	GO:0030252	growth hormone secretion	Ghrh	IDA		Mouse	PMID:15070777
Biological Process	GO:0030252	growth hormone secretion	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:15985453
Biological Process	GO:0030252	growth hormone secretion	Ghrh	IMP		Mouse	PMID:9348175
Biological Process	GO:0030252	growth hormone secretion	Ghrh	IMP		Rat	PMID:12587674\|RGD:1624952
Biological Process	GO:0046879	hormone secretion	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:16246898
Biological Process	GO:0046879	hormone secretion	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:15985453
Biological Process	GO:0035264	multicellular organism growth	GHRH	IMP		Human	PMID:8421089
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	Ghrh	IMP		Rat	PMID:19293247\|RGD:2325187
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	Ghrh	IMP		Rat	PMID:20133784\|RGD:2325186
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Ghrh	IDA		Rat	PMID:10579333\|RGD:1624957
Biological Process	GO:0008284	positive regulation of cell population proliferation	GHRH	IDA		Human	PMID:12867592
Biological Process	GO:0008284	positive regulation of cell population proliferation	Ghrh	IMP		Mouse	MGI:MGI:3833824\|PMID:11773624
Biological Process	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	Ghrh	IMP		Rat	PMID:19889861\|RGD:2325188
Biological Process	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	Ghrh	IMP		Rat	PMID:20237285\|RGD:10401262
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Ghrh	IDA		Rat	PMID:12213318\|RGD:1624955
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Ghrh	IMP		Rat	PMID:18363807\|RGD:2325189
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ghrh	IDA		Rat	PMID:14664705\|RGD:1601331
Biological Process	GO:0060124	positive regulation of growth hormone secretion	GHRH	IDA		Human	PMID:3008329
Biological Process	GO:0060124	positive regulation of growth hormone secretion	GHRH	IMP		Human	PMID:15538933
Biological Process	GO:0060124	positive regulation of growth hormone secretion	GHRH	IDA		Human	PMID:18329818
Biological Process	GO:0060124	positive regulation of growth hormone secretion	GHRH	IDA		Human	PMID:8421089
Biological Process	GO:0060124	positive regulation of growth hormone secretion	Ghrh	IDA		Rat	PMID:10579333\|RGD:1624957
Biological Process	GO:0060124	positive regulation of growth hormone secretion	Ghrh	IDA		Rat	PMID:6130528\|RGD:5687318
Biological Process	GO:0046887	positive regulation of hormone secretion	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:15985453
Biological Process	GO:0046887	positive regulation of hormone secretion	Ghrh	IMP		Mouse	PMID:9348175
Biological Process	GO:0046887	positive regulation of hormone secretion	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:16246898
Biological Process	GO:0040018	positive regulation of multicellular organism growth	GHRH	IMP		Human	PMID:8421089
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Ghrh	IGI	MGI:MGI:95707	Mouse	PMID:16246898
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:15985453
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Ghrh	IMP	MGI:MGI:3051561	Mouse	PMID:16246898
Biological Process	GO:0071548	response to dexamethasone	Ghrh	IEP		Rat	PMID:22067322\|RGD:10401243
Biological Process	GO:0032094	response to food	Ghrh	IDA		Mouse	PMID:16513828
Biological Process	GO:0001666	response to hypoxia	Ghrh	IEP		Rat	PMID:21180161\|RGD:5687743
Biological Process	GO:0044321	response to leptin	Ghrh	IEP		Rat	PMID:18806317\|RGD:5687187
Biological Process	GO:0007165	signal transduction	ghrh	IDA		Zfish	PMID:17283332

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.