Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GID8
  • Mouse genes Gid8
  • Rat genes Gid8
  • Zfish genes gid8a,gid8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gid8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GID8	IPI	UniProtKB:Q8IUR7-6	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	GID8	IPI	UniProtKB:Q9H871	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	GID8	IPI	UniProtKB:Q9H871	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GID8	IPI	UniProtKB:O15169|UniProtKB:P35222|UniProtKB:P49841	Human	PMID:28829046
Molecular Function	GO:0005515	protein binding	GID8	IPI	UniProtKB:Q8IUR7-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GID8	IPI	UniProtKB:Q9H871	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	Gid8	IDA		Mouse	MGI:MGI:6189381|PMID:27920276
Cellular Component	GO:0030054	cell junction	GID8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	GID8	IDA		Human	PMID:17467196
Cellular Component	GO:0005829	cytosol	GID8	IDA		Human	PMID:24143168
Cellular Component	GO:0005654	nucleoplasm	GID8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GID8	IDA		Human	PMID:17467196
Cellular Component	GO:0005634	nucleus	GID8	IDA		Human	PMID:24143168
Cellular Component	GO:0005634	nucleus	GID8	IDA		Human	PMID:28829046
Cellular Component	GO:0005634	nucleus	GID8	IDA		Human	PMID:29911972
Cellular Component	GO:0000151	ubiquitin ligase complex	GID8	IDA		Human	PMID:29911972
Biological Process	GO:0048263	determination of dorsal identity	gid8b	IMP	ZFIN:ZDB-MRPHLNO-180503-2	Zfish	PMID:28829046
Biological Process	GO:0048263	determination of dorsal identity	gid8a	IMP	ZFIN:ZDB-MRPHLNO-180503-3	Zfish	PMID:28829046
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	GID8	IMP		Human	PMID:28829046
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	gid8b	IMP		Zfish	PMID:28829046|ZFIN:ZDB-PUB-170823-5
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	gid8a	IMP		Zfish	PMID:28829046|ZFIN:ZDB-PUB-170823-5
Biological Process	GO:0008284	positive regulation of cell population proliferation	GID8	IMP		Human	PMID:28829046

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern