Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GIPC1
  • Mouse genes Gipc1
  • Rat genes Gipc1
  • Zfish genes gipc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gipc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Gipc1	IPI	PR:P68134	Mouse	PMID:15975910
Molecular Function	GO:0045296	cadherin binding	GIPC1	HDA		Human	PMID:25468996
Molecular Function	GO:0042802	identical protein binding	Gipc1	IPI	PR:Q9Z0G0	Mouse	PMID:15975910
Molecular Function	GO:0004707	MAP kinase activity	gipc1	IMP	ZFIN:ZDB-MRPHLNO-060726-1	Zfish	PMID:20237411
Molecular Function	GO:0017022	myosin binding	Gipc1	IPI	UniProtKB:Q14784	Mouse	PMID:16908842
Molecular Function	GO:0030165	PDZ domain binding	Gipc1	IPI	RGD:2521	Rat	PMID:14617818|RGD:1581465
Molecular Function	GO:0005515	protein binding	GIPC1	IPI	UniProtKB:P17643	Human	PMID:11441007
Molecular Function	GO:0005515	protein binding	GIPC1	IPI	UniProtKB:Q03167	Human	PMID:11546783
Molecular Function	GO:0005515	protein binding	GIPC1	IPI	UniProtKB:P31751,UniProtKB:Q9UKG1	Human	PMID:21291857
Molecular Function	GO:0005515	protein binding	GIPC1	IPI	UniProtKB:Q9UKG1	Human	PMID:21291857
Molecular Function	GO:0005515	protein binding	GIPC1	IPI	UniProtKB:Q9HB19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GIPC1	IPI	UniProtKB:P49795	Human	PMID:9770488
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	UniProtKB:Q64151	Mouse	MGI:MGI:1889199|PMID:10318831
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	UniProtKB:Q9UM54	Mouse	MGI:MGI:3663985|PMID:16908842
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	UniProtKB:A2ARV4	Mouse	MGI:MGI:3687813|PMID:10827173
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	UniProtKB:O88393	Mouse	MGI:MGI:3807767|PMID:11546783
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:Q66T02	Mouse	PMID:16467373
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:Q9CX84	Mouse	PMID:9770488
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:Q62179	Mouse	PMID:15978582
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	MGI:MGI:104785	Mouse	PMID:15975910
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:P68134	Mouse	PMID:15975910
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:P97333	Mouse	PMID:15978582
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:Q9CZN4	Mouse	PMID:24498314
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:P17809	Mouse	PMID:15975910
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:Q60575	Mouse	PMID:15975910
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	PR:P15209	Mouse	PMID:16819522
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	RGD:2520	Rat	PMID:14617818|RGD:1581465
Molecular Function	GO:0005515	protein binding	Gipc1	IPI	UniProtKB:Q6RFZ7	Rat	PMID:16467373|RGD:8553644
Molecular Function	GO:0005102	signaling receptor binding	GIPC1	IPI	UniProtKB:Q9NPY3	Human	PMID:15459234
Cellular Component	GO:0005903	brush border	Gipc1	IDA		Rat	PMID:11912251|RGD:2303813
Cellular Component	GO:0005938	cell cortex	GIPC1	IDA		Human	PMID:12857860
Cellular Component	GO:0005737	cytoplasm	Gipc1	IDA		Mouse	PMID:16819522
Cellular Component	GO:0031410	cytoplasmic vesicle	GIPC1	IDA		Human	PMID:12857860
Cellular Component	GO:0005829	cytosol	Gipc1	IDA		Mouse	PMID:9770488
Cellular Component	GO:0005829	cytosol	Gipc1	IDA		Rat	PMID:11912251|RGD:2303813
Cellular Component	GO:0043198	dendritic shaft	Gipc1	IDA		Mouse	PMID:16819522
Cellular Component	GO:0043197	dendritic spine	Gipc1	IDA		Mouse	PMID:16819522
Cellular Component	GO:0030139	endocytic vesicle	Gipc1	IDA		Rat	PMID:14617818|RGD:1581465
Cellular Component	GO:0070062	extracellular exosome	GIPC1	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Gipc1	IDA		Mouse	PMID:16819522
Cellular Component	GO:0098978	glutamatergic synapse	Gipc1	IMP		Mouse	PMID:16819522
Cellular Component	GO:0016020	membrane	GIPC1	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Gipc1	IDA		Mouse	PMID:9770488
Cellular Component	GO:0016020	membrane	Gipc1	IDA		Rat	PMID:11912251|RGD:2303813
Cellular Component	GO:0098794	postsynapse	Gipc1	IDA		Rat	PMID:16819522|RGD:155230717
Cellular Component	GO:0098793	presynapse	Gipc1	IDA		Mouse	MGI:MGI:3654775|PMID:16819522
Cellular Component	GO:0098793	presynapse	Gipc1	IDA		Rat	PMID:16819522|RGD:155230717
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Gipc1	IDA		Mouse	PMID:16819522
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Gipc1	IMP		Mouse	PMID:16819522
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Gipc1	IDA		Rat	PMID:16819522|RGD:155230717
Cellular Component	GO:0008021	synaptic vesicle	Gipc1	IDA		Mouse	PMID:16819522
Cellular Component	GO:0012506	vesicle membrane	Gipc1	IDA		Mouse	PMID:15975910
Biological Process	GO:0001525	angiogenesis	gipc1	IMP	ZFIN:ZDB-MRPHLNO-060726-1	Zfish	PMID:20237411
Biological Process	GO:0001525	angiogenesis	gipc1	IMP		Zfish	PMID:16754745
Biological Process	GO:0048844	artery morphogenesis	gipc1	IMP	ZFIN:ZDB-MRPHLNO-060726-1	Zfish	PMID:16740480
Biological Process	GO:0098761	cellular response to interleukin-7	Gipc1	IDA		Mouse	PMID:29581031
Biological Process	GO:0007268	chemical synaptic transmission	Gipc1	IMP	MGI:MGI:3663921	Mouse	PMID:16819522
Biological Process	GO:0043542	endothelial cell migration	Gipc1	IMP		Mouse	PMID:16467373
Biological Process	GO:0014047	glutamate secretion	Gipc1	IMP	MGI:MGI:3663921	Mouse	PMID:16819522
Biological Process	GO:0001946	lymphangiogenesis	gipc1	IMP	ZFIN:ZDB-MRPHLNO-060726-1,ZFIN:ZDB-MRPHLNO-060726-2	Zfish	PMID:20631376
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Gipc1	IDA		Mouse	MGI:MGI:3807767|PMID:11546783
Biological Process	GO:0032467	positive regulation of cytokinesis	GIPC1	IMP		Human	PMID:22888021
Biological Process	GO:0048023	positive regulation of melanin biosynthetic process	GIPC1	IMP		Human	PMID:21291857
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	Gipc1	IDA		Mouse	MGI:MGI:3807767|PMID:11546783
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Gipc1	IDA		Mouse	PMID:16819522
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Gipc1	IMP		Mouse	PMID:16819522
Biological Process	GO:0006605	protein targeting	Gipc1	IMP		Mouse	PMID:16467373
Biological Process	GO:0006605	protein targeting	Gipc1	IPI	PR:Q64331	Mouse	PMID:15975910
Biological Process	GO:0031647	regulation of protein stability	Gipc1	IDA		Mouse	MGI:MGI:3807767|PMID:11546783
Biological Process	GO:0048167	regulation of synaptic plasticity	Gipc1	IMP	MGI:MGI:3663921	Mouse	PMID:16819522
Biological Process	GO:0002040	sprouting angiogenesis	gipc1	IGI	ZFIN:ZDB-GENE-040426-921	Zfish	PMID:31050647
Biological Process	GO:0002040	sprouting angiogenesis	gipc1	IGI	ZFIN:ZDB-GENE-040426-921,ZFIN:ZDB-GENE-040426-1828	Zfish	PMID:31050647

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern