Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Git1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GIT1
- Mouse genes Git1
- Rat genes Git1
- Zfish genes git1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Git1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043015	gamma-tubulin binding	GIT1	IDA		Human	PMID:27012601
Molecular Function	GO:0005096	GTPase activator activity	Git1	IDA		Rat	PMID:16439353\|RGD:11344921
Molecular Function	GO:0005096	GTPase activator activity	Git1	IDA		Rat	PMID:9826657\|RGD:68782
Molecular Function	GO:0042802	identical protein binding	Git1	IPI	RGD:69331	Rat	PMID:15212761\|RGD:1549447
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q14160	Human	PMID:15182672
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P42858	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q12873	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q5T3J3	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q99728	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q9P2H0	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P49023	Human	PMID:16628223
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q13153	Human	PMID:16628223
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q14155	Human	PMID:16628223
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P49024	Human	PMID:16717130
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q14155	Human	PMID:16787945
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P25098	Human	PMID:18369319
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q14160	Human	PMID:19041750
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q14155	Human	PMID:21295525
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P62993	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q96C92	Human	PMID:23108400
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q13153	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q13153	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q13153\|UniProtKB:Q14155	Human	PMID:27012601
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P49023	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	GIT1	IPI	UniProtKB:Q13153	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Git1	IPI	UniProtKB:Q9ES28	Mouse	MGI:MGI:3815295\|PMID:16959763
Molecular Function	GO:0005515	protein binding	Git1	IPI	UniProtKB:A2AIR5	Mouse	MGI:MGI:5545681\|PMID:24297929
Molecular Function	GO:0005515	protein binding	Git1	IPI	UniProtKB:Q9ES28	Mouse	MGI:MGI:5284757\|PMID:19022416
Molecular Function	GO:0005515	protein binding	Git1	IPI	PR:Q9ES28	Mouse	PMID:10428811
Molecular Function	GO:0005515	protein binding	Git1	IPI	UniProtKB:O35346\|UniProtKB:O55043\|UniProtKB:P97879\|UniProtKB:Q66H76\|UniProtKB:Q9JKS6	Rat	PMID:12473661\|RGD:9850090
Molecular Function	GO:0005515	protein binding	Git1	IPI	RGD:620000	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:0005515	protein binding	Git1	IPI	RGD:621667	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:0005515	protein binding	Git1	IPI	RGD:736143	Rat	PMID:15212761\|RGD:1549447
Molecular Function	GO:0005515	protein binding	Git1	IPI	UniProtKB:Q9ES28	Rat	PMID:21295525\|RGD:8553358
Molecular Function	GO:0005515	protein binding	Git1	IPI	UniProtKB:O55043\|UniProtKB:Q9R1M7	Rat	PMID:24297929\|RGD:42721994
Molecular Function	GO:0019903	protein phosphatase binding	Git1	IPI	RGD:3453	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:1990782	protein tyrosine kinase binding	Git1	IPI	RGD:3443	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:0044877	protein-containing complex binding	Git1	IPI	PR:O55033	Mouse	PMID:17310244
Molecular Function	GO:0044877	protein-containing complex binding	Git1	IPI	PR:Q9JLQ2	Mouse	PMID:17310244
Molecular Function	GO:0044877	protein-containing complex binding	Git1	IPI	PR:Q8CBF3	Mouse	PMID:17310244
Molecular Function	GO:0097110	scaffold protein binding	Git1	IPI	RGD:1305759	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:0031267	small GTPase binding	Git1	IDA		Rat	PMID:9826657\|RGD:68782
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	Git1	IDA		Rat	PMID:25284783\|RGD:13702191
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	Git1	IMP		Rat	PMID:25284783\|RGD:13702191
Cellular Component	GO:0044305	calyx of Held	Git1	IMP		Mouse	PMID:26637799
Cellular Component	GO:0044305	calyx of Held	Git1	IDA		Mouse	PMID:26637799
Cellular Component	GO:0005813	centrosome	GIT1	IDA		Human	PMID:27012601
Cellular Component	GO:0005829	cytosol	GIT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Git1	IDA		Rat	PMID:16439353\|RGD:11344921
Cellular Component	GO:0030425	dendrite	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0005768	endosome	Git1	IDA		Rat	PMID:18523162\|RGD:13513208
Cellular Component	GO:0060076	excitatory synapse	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0005925	focal adhesion	GIT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	GIT1	HDA		Human	PMID:21423176
Cellular Component	GO:0098982	GABA-ergic synapse	Git1	IDA		Rat	PMID:25284783\|RGD:13702191
Cellular Component	GO:0098982	GABA-ergic synapse	Git1	IMP		Rat	PMID:25284783\|RGD:13702191
Cellular Component	GO:0098978	glutamatergic synapse	Git1	IDA		Rat	PMID:25284783\|RGD:13702191
Cellular Component	GO:0030426	growth cone	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0060077	inhibitory synapse	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0016020	membrane	GIT1	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0005739	mitochondrion	GIT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0097431	mitotic spindle pole	GIT1	IDA		Human	PMID:27012601
Cellular Component	GO:0043005	neuron projection	Git1	IDA		Rat	PMID:12473661\|RGD:9850090
Cellular Component	GO:0098794	postsynapse	Git1	IDA		Mouse	MGI:MGI:5545681\|PMID:24297929
Cellular Component	GO:0098794	postsynapse	Git1	IDA		Rat	PMID:25284783\|RGD:13702191
Cellular Component	GO:0014069	postsynaptic density	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Cellular Component	GO:0098793	presynapse	Git1	IDA		Mouse	MGI:MGI:5708768\|PMID:26637799
Cellular Component	GO:0045202	synapse	Git1	IDA		Rat	PMID:12473661\|RGD:9850090
Cellular Component	GO:0045202	synapse	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Biological Process	GO:0001525	angiogenesis	git1	IMP	ZFIN:ZDB-MRPHLNO-120823-10	Zfish	PMID:22206757
Biological Process	GO:0001568	blood vessel development	git1	IMP	ZFIN:ZDB-MRPHLNO-120823-10	Zfish	PMID:22206757
Biological Process	GO:0001568	blood vessel development	git1	IMP	ZFIN:ZDB-MRPHLNO-120823-9	Zfish	PMID:22206757
Biological Process	GO:0007420	brain development	Git1	IMP		Mouse	MGI:MGI:6478058\|PMID:25792865
Biological Process	GO:0007420	brain development	Git1	IDA		Rat	PMID:12629171\|RGD:152995492
Biological Process	GO:0045454	cell redox homeostasis	Git1	IMP		Mouse	MGI:MGI:6478067\|PMID:32460388
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Git1	IDA		Rat	PMID:18523162\|RGD:13513208
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Git1	IMP		Mouse	MGI:MGI:6478067\|PMID:32460388
Biological Process	GO:0060996	dendritic spine development	Git1	IGI	UniProtKB:D4A3M8	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0060996	dendritic spine development	Git1	IGI	UniProtKB:P09759	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0048013	ephrin receptor signaling pathway	Git1	IDA		Mouse	PMID:17310244
Biological Process	GO:0001771	immunological synapse formation	Git1	IGI	UniProtKB:D4A3M8	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0001771	immunological synapse formation	Git1	IGI	UniProtKB:P09759	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0001957	intramembranous ossification	Git1	IMP		Mouse	MGI:MGI:6478067\|PMID:32460388
Biological Process	GO:0007626	locomotory behavior	Git1	IMP		Mouse	MGI:MGI:6478058\|PMID:25792865
Biological Process	GO:0061743	motor learning	Git1	IMP		Mouse	MGI:MGI:6478058\|PMID:25792865
Biological Process	GO:0032013	negative regulation of ARF protein signal transduction	Git1	IDA		Rat	PMID:16439353\|RGD:11344921
Biological Process	GO:0045820	negative regulation of glycolytic process	Git1	IMP		Mouse	MGI:MGI:6478067\|PMID:32460388
Biological Process	GO:0106015	negative regulation of inflammatory response to wounding	Git1	IMP		Mouse	MGI:MGI:6478067\|PMID:32460388
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	Git1	IMP		Mouse	MGI:MGI:6478067\|PMID:32460388
Biological Process	GO:0048666	neuron development	Git1	IMP		Mouse	MGI:MGI:6478058\|PMID:25792865
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Git1	IDA		Rat	PMID:25284783\|RGD:13702191
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Git1	IMP		Rat	PMID:25284783\|RGD:13702191
Biological Process	GO:0090063	positive regulation of microtubule nucleation	GIT1	IMP		Human	PMID:27012601
Biological Process	GO:2000646	positive regulation of receptor catabolic process	Git1	IMP		Rat	PMID:18523162\|RGD:13513208
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Git1	IDA		Mouse	PMID:26637799
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Git1	IMP		Mouse	PMID:26637799
Biological Process	GO:0032465	regulation of cytokinesis	GIT1	IDA		Human	PMID:23108400
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Git1	IDA		Rat	PMID:9826657\|RGD:68782
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Git1	IMP		Mouse	PMID:26637799
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Git1	IDA		Mouse	PMID:26637799

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.