Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GJA1
  • Mouse genes Gja1
  • Rat genes Gja1
  • Zfish genes gja1a,gja1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gja1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	GJA1	IPI	UniProtKB:P35222	Human	PMID:30992345
Molecular Function	GO:0048487	beta-tubulin binding	Gja1	IDA		Mouse	PMID:15084279
Molecular Function	GO:0071253	connexin binding	Gja1	IPI	RGD:2692	Rat	PMID:11557558|RGD:7207849
Molecular Function	GO:0097718	disordered domain specific binding	Gja1	IPI	UniProtKB:P28234	Rat	PMID:19808665|RGD:12793009
Molecular Function	GO:0015562	efflux transmembrane transporter activity	Gja1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Molecular Function	GO:0005243	gap junction channel activity	GJA1	IDA		Human	PMID:16790700
Molecular Function	GO:0005243	gap junction channel activity	GJA1	IDA		Human	PMID:1696265
Molecular Function	GO:0005243	gap junction channel activity	GJA1	IDA		Human	PMID:23348765
Molecular Function	GO:0005243	gap junction channel activity	Gja1	IMP		Mouse	MGI:MGI:6271573|PMID:29366904
Molecular Function	GO:0005243	gap junction channel activity	Gja1	IDA		Mouse	PMID:11397787
Molecular Function	GO:0005243	gap junction channel activity	Gja1	IDA		Mouse	PMID:15084279
Molecular Function	GO:0005243	gap junction channel activity	Gja1	IDA		Rat	PMID:15048573|RGD:1580399
Molecular Function	GO:0005243	gap junction channel activity	Gja1	IDA		Rat	PMID:15284189|RGD:12793029
Molecular Function	GO:0005243	gap junction channel activity	Gja1	IDA		Rat	PMID:16731531|RGD:1582674
Molecular Function	GO:0005243	gap junction channel activity	gja1a	IGI	ZFIN:ZDB-GENE-991105-4	Zfish	PMID:19808035
Molecular Function	GO:0005243	gap junction channel activity	gja1b	IDA		Zfish	PMID:19808035
Molecular Function	GO:0005243	gap junction channel activity	gja1b	IDA		Zfish	PMID:17599838
Molecular Function	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling	GJA1	IDA		Human	PMID:1696265
Molecular Function	GO:0055077	gap junction hemi-channel activity	GJA1	IMP		Human	PMID:29366904
Molecular Function	GO:0055077	gap junction hemi-channel activity	gja1b	IDA		Zfish	PMID:17599838
Molecular Function	GO:0034634	glutathione transmembrane transporter activity	Gja1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Molecular Function	GO:0060090	molecular adaptor activity	Gja1	EXP		Rat	PMID:15492000|RGD:12793032
Molecular Function	GO:0015075	monoatomic ion transmembrane transporter activity	GJA1	IDA		Human	PMID:1696265
Molecular Function	GO:0030165	PDZ domain binding	Gja1	IPI	UniProtKB:P39447	Rat	PMID:14699011|RGD:1582694
Molecular Function	GO:0030165	PDZ domain binding	Gja1	IPI	UniProtKB:P39447	Rat	PMID:15492000|RGD:12793032
Molecular Function	GO:0030165	PDZ domain binding	Gja1	IPI	RGD:1306305	Rat	PMID:15980428|RGD:1582683
Molecular Function	GO:0030165	PDZ domain binding	Gja1	IPI	RGD:619807	Rat	PMID:15980428|RGD:1582683
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q8VCZ6	Human	PMID:15709751
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q07157	Human	PMID:16944923
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q99683	Human	PMID:17761141
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q02487-1	Human	PMID:21220045
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:O43889-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:P19022	Human	PMID:29366904
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q07157	Human	PMID:29366904
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q07157	Human	PMID:30992345
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:O43889-2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q5BJH2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q5VZY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q9NZG7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q8TAB5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q9NP61	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GJA1	IPI	UniProtKB:Q07157	Human	PMID:9707407
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P16054	Mouse	MGI:MGI:5644028|PMID:11139474
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q7TT37	Mouse	MGI:MGI:6294172|PMID:28507509
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P15116	Mouse	MGI:MGI:6271573|PMID:29366904
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P39447	Mouse	MGI:MGI:5508268|PMID:16045494
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P05480|UniProtKB:P39447|UniProtKB:Q6NZM9|UniProtKB:Q9Z2V6	Mouse	MGI:MGI:4939823|PMID:21282606
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P68254	Mouse	MGI:MGI:5644009|PMID:24163432
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P39447	Mouse	MGI:MGI:5578691|PMID:24413171
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q6PF93|UniProtKB:Q8C0J2|UniProtKB:Q8CDJ3|UniProtKB:Q8VD65	Mouse	MGI:MGI:5915435|PMID:24705551
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P28229|UniProtKB:P28231	Mouse	MGI:MGI:3808971|PMID:18055446
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P28867	Mouse	MGI:MGI:5644021|PMID:20338032
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q4VAE3	Mouse	MGI:MGI:5699931|PMID:26403541
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P16054	Mouse	MGI:MGI:5644021|PMID:20338032
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q63664	Mouse	MGI:MGI:5644015|PMID:22960107
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P11688	Mouse	MGI:MGI:5314545|PMID:22331870
Molecular Function	GO:0005515	protein binding	Gja1	IPI	PR:Q9QXS6	Mouse	PMID:15084279
Molecular Function	GO:0005515	protein binding	Gja1	IPI	PR:Q9JJV9	Mouse	PMID:15272007
Molecular Function	GO:0005515	protein binding	Gja1	IPI	PR:P97952	Mouse	PMID:15272007
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P48745	Rat	PMID:15181016|RGD:10400869
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P48745	Rat	PMID:15213231|RGD:10400864
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q8VCZ6	Rat	PMID:15709751|RGD:8554661
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q562C0	Rat	PMID:17673670|RGD:6784510
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:P41350	Rat	PMID:18162583|RGD:8553801
Molecular Function	GO:0005515	protein binding	Gja1	IPI	RGD:1306305	Rat	PMID:19825979|RGD:2325130
Molecular Function	GO:0005515	protein binding	Gja1	IPI	RGD:1313643	Rat	PMID:19835873|RGD:9685535
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q9NRR5	Rat	PMID:20940304|RGD:10400851
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q63664	Rat	PMID:22960107|RGD:10047305
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:Q07266	Rat	PMID:27280719|RGD:14397581
Molecular Function	GO:0005515	protein binding	Gja1	IPI	UniProtKB:A0A0G2K2P5	Rat	PMID:29021339|RGD:13825187
Molecular Function	GO:0005515	protein binding	gja1b	IPI	ZFIN:ZDB-GENE-031001-2	Zfish	PMID:25915619
Molecular Function	GO:0019904	protein domain specific binding	Gja1	IDA		Rat	PMID:17008717|RGD:1601340
Molecular Function	GO:1990782	protein tyrosine kinase binding	Gja1	IPI	UniProtKB:P05480	Mouse	MGI:MGI:5882903|PMID:14699011
Molecular Function	GO:0097110	scaffold protein binding	Gja1	IPI	UniProtKB:P39447	Mouse	MGI:MGI:5882903|PMID:14699011
Molecular Function	GO:0097110	scaffold protein binding	Gja1	IPI	UniProtKB:P51637	Mouse	MGI:MGI:5448532|PMID:19544087
Molecular Function	GO:0017124	SH3 domain binding	Gja1	IDA		Rat	PMID:14699011|RGD:1582694
Molecular Function	GO:0017124	SH3 domain binding	Gja1	IPI	UniProtKB:P00523	Rat	PMID:14699011|RGD:1582694
Molecular Function	GO:0017124	SH3 domain binding	Gja1	IPI	UniProtKB:P00523	Rat	PMID:15492000|RGD:12793032
Molecular Function	GO:0005102	signaling receptor binding	Gja1	IPI	PR:Q9Z1M0	Mouse	PMID:15331634
Molecular Function	GO:0015631	tubulin binding	GJA1	IDA		Human	PMID:22558917
Molecular Function	GO:0022832	voltage-gated channel activity	gja1b	IDA		Zfish	PMID:17599838
Cellular Component	GO:0016324	apical plasma membrane	Gja1	IDA		Mouse	MGI:MGI:6271573|PMID:29366904
Cellular Component	GO:0016324	apical plasma membrane	Gja1	IDA		Mouse	PMID:9620080
Cellular Component	GO:0030054	cell junction	GJA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030054	cell junction	GJA1	IDA		Human	PMID:29366904
Cellular Component	GO:0030054	cell junction	Gja1	IDA		Mouse	PMID:15601660
Cellular Component	GO:0044291	cell-cell contact zone	GJA1	IDA		Human	PMID:11090614
Cellular Component	GO:0005911	cell-cell junction	Gja1	IDA		Mouse	PMID:21296051
Cellular Component	GO:0005911	cell-cell junction	Gja1	IDA		Mouse	PMID:15331634
Cellular Component	GO:0005911	cell-cell junction	Gja1	IDA		Mouse	PMID:15084279
Cellular Component	GO:0005922	connexin complex	Gja1	IDA		Rat	PMID:15048573|RGD:1580399
Cellular Component	GO:0005922	connexin complex	Gja1	IDA		Rat	PMID:16731531|RGD:1582674
Cellular Component	GO:0005922	connexin complex	Gja1	IDA		Rat	PMID:9851942|RGD:1598435
Cellular Component	GO:0005922	connexin complex	Gja1	IDA		Rat	PMID:1371548|RGD:14397551
Cellular Component	GO:0005922	connexin complex	Gja1	IDA		Rat	PMID:15284189|RGD:12793029
Cellular Component	GO:0005922	connexin complex	Gja1	IMP		Rat	PMID:19808665|RGD:12793009
Cellular Component	GO:0043292	contractile fiber	Gja1	IDA		Mouse	PMID:21708977
Cellular Component	GO:0005737	cytoplasm	GJA1	IDA		Human	PMID:30599359
Cellular Component	GO:0005737	cytoplasm	Gja1	IDA		Mouse	PMID:9620080
Cellular Component	GO:0005737	cytoplasm	Gja1	IDA		Rat	PMID:16731531|RGD:1582674
Cellular Component	GO:0005829	cytosol	Gja1	IDA		Mouse	PMID:15331634
Cellular Component	GO:0005769	early endosome	Gja1	IDA		Rat	PMID:16162097|RGD:1582681
Cellular Component	GO:0005768	endosome	Gja1	IDA		Rat	PMID:19808888|RGD:4892648
Cellular Component	GO:0005916	fascia adherens	Gja1	IDA		Mouse	PMID:11732910
Cellular Component	GO:0005916	fascia adherens	Gja1	IDA		Rat	PMID:16515795|RGD:1582675
Cellular Component	GO:0005916	fascia adherens	Gja1	IDA		Rat	PMID:9851942|RGD:1598435
Cellular Component	GO:0005925	focal adhesion	GJA1	HDA		Human	PMID:21423176
Cellular Component	GO:0005921	gap junction	GJA1	IDA		Human	PMID:1696265
Cellular Component	GO:0005921	gap junction	GJA1	IDA		Human	PMID:23348765
Cellular Component	GO:0005921	gap junction	GJA1	IDA		Human	PMID:30599359
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Mouse	MGI:MGI:71881|PMID:7892609
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Mouse	PMID:14595769
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Mouse	PMID:11922902
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Mouse	PMID:15084279
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Mouse	PMID:20086016
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Mouse	PMID:20089884
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Mouse	PMID:12738802
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Rat	PMID:15048573|RGD:1580399
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Rat	PMID:15709751|RGD:8554661
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Rat	PMID:16565306|RGD:1601342
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Rat	PMID:16731531|RGD:1582674
Cellular Component	GO:0005921	gap junction	Gja1	IDA		Rat	PMID:19808888|RGD:4892648
Cellular Component	GO:0005921	gap junction	gja1a	IGI	ZFIN:ZDB-GENE-991105-4	Zfish	PMID:19808035
Cellular Component	GO:0005921	gap junction	gja1b	IDA		Zfish	PMID:19808035
Cellular Component	GO:0005794	Golgi apparatus	Gja1	IDA		Mouse	PMID:15084279
Cellular Component	GO:0005794	Golgi apparatus	Gja1	IDA		Rat	PMID:18162583|RGD:8553801
Cellular Component	GO:0014704	intercalated disc	GJA1	IDA		Human	PMID:22889254
Cellular Component	GO:0014704	intercalated disc	GJA1	IDA		Human	PMID:23381804
Cellular Component	GO:0014704	intercalated disc	Gja1	IDA		Mouse	MGI:MGI:3763979|PMID:17884088
Cellular Component	GO:0014704	intercalated disc	Gja1	IDA		Mouse	MGI:MGI:5699931|PMID:26403541
Cellular Component	GO:0014704	intercalated disc	Gja1	IDA		Mouse	PMID:15272007
Cellular Component	GO:0014704	intercalated disc	Gja1	IDA		Mouse	PMID:27799555
Cellular Component	GO:0014704	intercalated disc	Gja1	IDA		Mouse	PMID:18178574
Cellular Component	GO:0005882	intermediate filament	Gja1	IDA		Mouse	MGI:MGI:3723417|PMID:16917092
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GJA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005770	late endosome	Gja1	IDA		Rat	PMID:16162097|RGD:1582681
Cellular Component	GO:0016328	lateral plasma membrane	Gja1	IDA		Mouse	PMID:9620080
Cellular Component	GO:0005764	lysosome	Gja1	IDA		Rat	PMID:16162097|RGD:1582681
Cellular Component	GO:0016020	membrane	Gja1	IDA		Mouse	PMID:15084279
Cellular Component	GO:0016020	membrane	Gja1	IDA		Rat	PMID:19723622|RGD:8554041
Cellular Component	GO:0045121	membrane raft	Gja1	IDA		Rat	PMID:18162583|RGD:8553801
Cellular Component	GO:0005741	mitochondrial outer membrane	Gja1	IDA		Rat	PMID:17107662|RGD:1601339
Cellular Component	GO:0005739	mitochondrion	GJA1	IDA		Human	PMID:15919068
Cellular Component	GO:0005739	mitochondrion	GJA1	IDA		Human	PMID:29163229
Cellular Component	GO:0005771	multivesicular body	Gja1	IDA		Rat	PMID:16162097|RGD:1582681
Cellular Component	GO:0005654	nucleoplasm	GJA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GJA1	IDA		Human	PMID:11090614
Cellular Component	GO:0005886	plasma membrane	GJA1	IDA		Human	PMID:30599359
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Mouse	MGI:MGI:5882903|PMID:14699011
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Mouse	MGI:MGI:5699931|PMID:26403541
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Mouse	PMID:15331634
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Mouse	PMID:17164264
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Mouse	PMID:15084279
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Rat	PMID:16515795|RGD:1582675
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Rat	PMID:16565306|RGD:1601342
Cellular Component	GO:0005886	plasma membrane	Gja1	IMP		Rat	PMID:17673670|RGD:6784510
Cellular Component	GO:0005886	plasma membrane	Gja1	IDA		Rat	PMID:18162583|RGD:8553801
Cellular Component	GO:0005886	plasma membrane	gja1a	IGI	ZFIN:ZDB-GENE-991105-4	Zfish	PMID:19808035
Cellular Component	GO:0005886	plasma membrane	gja1b	IDA		Zfish	PMID:17599838
Cellular Component	GO:0005886	plasma membrane	gja1b	IDA		Zfish	PMID:18406403
Cellular Component	GO:0032991	protein-containing complex	Gja1	IMP		Rat	PMID:15492000|RGD:12793032
Cellular Component	GO:0070160	tight junction	GJA1	IDA		Human	PMID:30992345
Biological Process	GO:0007512	adult heart development	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:9486664
Biological Process	GO:0006915	apoptotic process	Gja1	IMP		Rat	PMID:17107662|RGD:1601339
Biological Process	GO:0015867	ATP transport	Gja1	IMP		Rat	PMID:16731531|RGD:1582674
Biological Process	GO:0003294	atrial ventricular junction remodeling	Gja1	IGI	MGI:MGI:95716	Mouse	PMID:10969038
Biological Process	GO:0048514	blood vessel morphogenesis	Gja1	IMP	MGI:MGI:2386570,MGI:MGI:3051881	Mouse	PMID:16624854
Biological Process	GO:0060348	bone development	Gja1	IMP		Mouse	MGI:MGI:6274948|PMID:25270829
Biological Process	GO:0098868	bone growth	gja1b	IMP		Zfish	PMID:27129238
Biological Process	GO:0060349	bone morphogenesis	gja1b	IMP		Zfish	PMID:27129238
Biological Process	GO:0060349	bone morphogenesis	gja1b	IMP	ZFIN:ZDB-GENO-141205-2	Zfish	PMID:24173565
Biological Process	GO:0046849	bone remodeling	Gja1	IMP		Mouse	MGI:MGI:6274948|PMID:25270829
Biological Process	GO:0061337	cardiac conduction	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:9109444
Biological Process	GO:0061337	cardiac conduction	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:10969038
Biological Process	GO:0035143	caudal fin morphogenesis	gja1b	IMP	ZFIN:ZDB-GENO-050222-1	Zfish	PMID:15649473
Biological Process	GO:0035143	caudal fin morphogenesis	gja1b	IMP	ZFIN:ZDB-GENO-050222-3	Zfish	PMID:15649473
Biological Process	GO:0035143	caudal fin morphogenesis	gja1b	IMP	ZFIN:ZDB-GENO-980202-318	Zfish	PMID:15649473
Biological Process	GO:0035143	caudal fin morphogenesis	gja1b	IMP	ZFIN:ZDB-GENO-050222-2	Zfish	PMID:15649473
Biological Process	GO:0007154	cell communication	Gja1	IMP		Rat	PMID:15685554|RGD:1582688
Biological Process	GO:0007154	cell communication	gja1b	IDA		Zfish	PMID:17599838
Biological Process	GO:0010643	cell communication by chemical coupling	Gja1	IDA		Mouse	PMID:15084279
Biological Process	GO:0010644	cell communication by electrical coupling	GJA1	IDA		Human	PMID:16790700
Biological Process	GO:0010644	cell communication by electrical coupling	GJA1	IDA		Human	PMID:1696265
Biological Process	GO:0010644	cell communication by electrical coupling	GJA1	IDA		Human	PMID:23348765
Biological Process	GO:0010644	cell communication by electrical coupling	Gja1	IDA		Mouse	PMID:15084279
Biological Process	GO:0008283	cell population proliferation	gja1b	IMP	ZFIN:ZDB-GENO-080916-5	Zfish	PMID:18406403
Biological Process	GO:0008283	cell population proliferation	gja1b	IMP	ZFIN:ZDB-GENO-080916-7	Zfish	PMID:18406403
Biological Process	GO:0008283	cell population proliferation	gja1b	IMP	ZFIN:ZDB-MRPHLNO-080818-1	Zfish	PMID:18406403
Biological Process	GO:0008283	cell population proliferation	gja1b	IMP	ZFIN:ZDB-GENO-080916-6	Zfish	PMID:18406403
Biological Process	GO:0008283	cell population proliferation	gja1b	IMP	ZFIN:ZDB-GENO-080915-2	Zfish	PMID:18406403
Biological Process	GO:0008283	cell population proliferation	gja1b	IMP	ZFIN:ZDB-MRPHLNO-050304-1	Zfish	PMID:18406403
Biological Process	GO:0045216	cell-cell junction organization	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:9620080
Biological Process	GO:0007267	cell-cell signaling	GJA1	IDA		Human	PMID:1696265
Biological Process	GO:0007267	cell-cell signaling	Gja1	IDA		Mouse	PMID:11397787
Biological Process	GO:0007267	cell-cell signaling	Gja1	IDA		Rat	PMID:15048573|RGD:1580399
Biological Process	GO:1904646	cellular response to amyloid-beta	Gja1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Biological Process	GO:0071260	cellular response to mechanical stimulus	Gja1	IEP		Rat	PMID:10631100|RGD:7207855
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Gja1	IEP		Rat	PMID:11159864|RGD:12910137
Biological Process	GO:0071467	cellular response to pH	Gja1	IDA		Mouse	MGI:MGI:5882903|PMID:14699011
Biological Process	GO:0002544	chronic inflammatory response	Gja1	IMP		Rat	PMID:23165424|RGD:7207259
Biological Process	GO:0002069	columnar/cuboidal epithelial cell maturation	Gja1	IMP	MGI:MGI:2176205,MGI:MGI:3051881	Mouse	PMID:16624854
Biological Process	GO:0046697	decidualization	Gja1	IEP		Rat	PMID:8924512|RGD:11568668
Biological Process	GO:0042733	embryonic digit morphogenesis	Gja1	IMP	MGI:MGI:2445472	Mouse	PMID:19439426
Biological Process	GO:0035050	embryonic heart tube development	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:14732399
Biological Process	GO:0035050	embryonic heart tube development	gja1b	IMP	ZFIN:ZDB-MRPHLNO-050304-1	Zfish	PMID:15649473
Biological Process	GO:0035162	embryonic hemopoiesis	gja1b	IMP	ZFIN:ZDB-MRPHLNO-050304-1	Zfish	PMID:15649473
Biological Process	GO:0035162	embryonic hemopoiesis	gja1b	IMP		Zfish	PMID:20020200
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	gja1b	IMP	ZFIN:ZDB-GENO-080206-1,ZFIN:ZDB-MRPHLNO-080818-1	Zfish	PMID:19150347
Biological Process	GO:0003158	endothelium development	Gja1	IEP		Rat	PMID:10990491|RGD:7207853
Biological Process	GO:1905867	epididymis development	Gja1	IEP		Rat	PMID:12388089|RGD:628541
Biological Process	GO:0000132	establishment of mitotic spindle orientation	GJA1	IMP		Human	PMID:30992345
Biological Process	GO:0140115	export across plasma membrane	Gja1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Biological Process	GO:0033333	fin development	gja1b	IMP	ZFIN:ZDB-GENO-180503-22	Zfish	PMID:28835471
Biological Process	GO:0033334	fin morphogenesis	gja1b	IGI	ZFIN:ZDB-GENO-140227-3,ZFIN:ZDB-MRPHLNO-080818-1	Zfish	PMID:24278401
Biological Process	GO:0031101	fin regeneration	gja1b	IGI	ZFIN:ZDB-GENE-991105-4	Zfish	PMID:29084713
Biological Process	GO:0031101	fin regeneration	gja1b	IGI	ZFIN:ZDB-GENE-030131-3196	Zfish	PMID:29084713
Biological Process	GO:0031101	fin regeneration	gja1b	IMP	ZFIN:ZDB-MRPHLNO-070819-2	Zfish	PMID:29084713
Biological Process	GO:0031101	fin regeneration	gja1b	IMP	ZFIN:ZDB-GENO-080915-2	Zfish	PMID:18406403
Biological Process	GO:0031101	fin regeneration	gja1b	IMP	ZFIN:ZDB-MRPHLNO-080818-1	Zfish	PMID:18406403
Biological Process	GO:0031101	fin regeneration	gja1b	IGI	ZFIN:ZDB-GENO-120514-7,ZFIN:ZDB-MRPHLNO-110713-1	Zfish	PMID:26434741
Biological Process	GO:0031101	fin regeneration	gja1b	IMP	ZFIN:ZDB-MRPHLNO-050304-1	Zfish	PMID:18406403
Biological Process	GO:0014047	glutamate secretion	Gja1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Biological Process	GO:0060047	heart contraction	gja1b	IMP	ZFIN:ZDB-MRPHLNO-201130-2	Zfish	PMID:33549680
Biological Process	GO:0060047	heart contraction	gja1b	IGI	ZFIN:ZDB-MRPHLNO-220307-2,ZFIN:ZDB-MRPHLNO-201130-2	Zfish	PMID:33549680
Biological Process	GO:0007507	heart development	Gja1	IMP		Mouse	MGI:MGI:71881|PMID:7892609
Biological Process	GO:0007507	heart development	Gja1	IMP	MGI:MGI:2176205,MGI:MGI:3051881	Mouse	PMID:16624854
Biological Process	GO:0007507	heart development	Gja1	IEP		Rat	PMID:8944820|RGD:7207856
Biological Process	GO:0001947	heart looping	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:9486664
Biological Process	GO:0001701	in utero embryonic development	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:9486664
Biological Process	GO:0070121	Kupffer's vesicle development	gja1b	IMP	ZFIN:ZDB-MRPHLNO-100518-3	Zfish	PMID:19799895
Biological Process	GO:0002088	lens development in camera-type eye	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:9620080
Biological Process	GO:0035437	maintenance of protein localization in endoplasmic reticulum	Gja1	IDA		Rat	PMID:15817491|RGD:1582686
Biological Process	GO:0008584	male gonad development	Gja1	IMP		Mouse	MGI:MGI:3715585|PMID:17591950
Biological Process	GO:0033338	medial fin development	gja1b	IMP	ZFIN:ZDB-GENO-180503-22	Zfish	PMID:28835471
Biological Process	GO:0060156	milk ejection reflex	Gja1	IMP	MGI:MGI:2682016	Mouse	PMID:20089884
Biological Process	GO:0034220	monoatomic ion transmembrane transport	GJA1	IDA		Human	PMID:1696265
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	Gja1	IMP		Rat	PMID:19377854|RGD:7207421
Biological Process	GO:0030308	negative regulation of cell growth	Gja1	IMP		Mouse	MGI:MGI:5688844|PMID:15181016
Biological Process	GO:0030308	negative regulation of cell growth	Gja1	IMP		Rat	PMID:15181016|RGD:10400869
Biological Process	GO:0008285	negative regulation of cell population proliferation	Gja1	IDA		Rat	PMID:12952975|RGD:1582696
Biological Process	GO:2000279	negative regulation of DNA biosynthetic process	Gja1	IDA		Rat	PMID:14702389|RGD:8662403
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	Gja1	IMP		Rat	PMID:18172080|RGD:8662378
Biological Process	GO:0010629	negative regulation of gene expression	Gja1	IMP	MGI:MGI:2445472	Mouse	PMID:19439426
Biological Process	GO:0032277	negative regulation of gonadotropin secretion	GJA1	IMP		Human	PMID:30599359
Biological Process	GO:1901164	negative regulation of trophoblast cell migration	GJA1	IMP		Human	PMID:30599359
Biological Process	GO:0061045	negative regulation of wound healing	Gja1	IMP		Rat	PMID:18172080|RGD:8662378
Biological Process	GO:0097402	neuroblast migration	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:12638734
Biological Process	GO:0001764	neuron migration	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:12638734
Biological Process	GO:0048812	neuron projection morphogenesis	Gja1	IMP		Rat	PMID:16731531|RGD:1582674
Biological Process	GO:0001649	osteoblast differentiation	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:21934140
Biological Process	GO:0001649	osteoblast differentiation	Gja1	IMP	MGI:MGI:3776013	Mouse	PMID:12606326
Biological Process	GO:0001649	osteoblast differentiation	Gja1	IMP	MGI:MGI:2445468	Mouse	PMID:12606326
Biological Process	GO:2000987	positive regulation of behavioral fear response	Gja1	IMP		Rat	PMID:22665389|RGD:7207267
Biological Process	GO:0010652	positive regulation of cell communication by chemical coupling	Gja1	IMP		Rat	PMID:15678088|RGD:7207816
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Gja1	IMP		Mouse	MGI:MGI:6101076|PMID:27626200
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Gja1	IMP		Rat	PMID:22577485|RGD:7207268
Biological Process	GO:1904446	positive regulation of establishment of Sertoli cell barrier	Gja1	IMP		Rat	PMID:26678449|RGD:11532443
Biological Process	GO:0010628	positive regulation of gene expression	GJA1	IMP		Human	PMID:28342807
Biological Process	GO:0010628	positive regulation of gene expression	Gja1	IMP	MGI:MGI:2445472	Mouse	PMID:19439426
Biological Process	GO:0003104	positive regulation of glomerular filtration	Gja1	IMP		Rat	PMID:18046320|RGD:7207467
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	GJA1	HMP		Human	PMID:12761501
Biological Process	GO:0032024	positive regulation of insulin secretion	Gja1	IMP		Rat	PMID:24301293|RGD:8662441
Biological Process	GO:0045836	positive regulation of meiotic nuclear division	Gja1	IMP		Rat	PMID:26678449|RGD:11532443
Biological Process	GO:1905772	positive regulation of mesodermal cell differentiation	GJA1	IMP		Human	PMID:30599359
Biological Process	GO:1905332	positive regulation of morphogenesis of an epithelium	GJA1	IMP		Human	PMID:30992345
Biological Process	GO:0045732	positive regulation of protein catabolic process	Gja1	IDA		Rat	PMID:12952975|RGD:1582696
Biological Process	GO:2000648	positive regulation of stem cell proliferation	GJA1	IMP		Human	PMID:30599359
Biological Process	GO:0045844	positive regulation of striated muscle tissue development	Gja1	IMP	MGI:MGI:2676327	Mouse	PMID:15601660
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	GJA1	IMP		Human	PMID:28342807
Biological Process	GO:0045907	positive regulation of vasoconstriction	Gja1	IMP		Rat	PMID:21414209|RGD:7207411
Biological Process	GO:0008104	protein localization	GJA1	IMP	UniProtKB:Q07157	Human	PMID:30992345
Biological Process	GO:0110053	regulation of actin filament organization	Gja1	IMP		Rat	PMID:26678449|RGD:11532443
Biological Process	GO:0042981	regulation of apoptotic process	Gja1	IMP		Rat	PMID:17761141|RGD:14397586
Biological Process	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:10969038
Biological Process	GO:2000810	regulation of bicellular tight junction assembly	Gja1	IMP		Rat	PMID:19509333|RGD:6784505
Biological Process	GO:0030500	regulation of bone mineralization	Gja1	IMP	MGI:MGI:3776013	Mouse	PMID:21346198
Biological Process	GO:0030500	regulation of bone mineralization	Gja1	IMP	MGI:MGI:2445468	Mouse	PMID:21346198
Biological Process	GO:0046850	regulation of bone remodeling	Gja1	IMP	MGI:MGI:2445468	Mouse	PMID:21346198
Biological Process	GO:0046850	regulation of bone remodeling	Gja1	IMP	MGI:MGI:3776013	Mouse	PMID:21346198
Biological Process	GO:0051924	regulation of calcium ion transport	Gja1	IMP		Rat	PMID:16878174|RGD:1601341
Biological Process	GO:0010649	regulation of cell communication by electrical coupling	Gja1	IDA		Rat	PMID:11557558|RGD:7207849
Biological Process	GO:0008016	regulation of heart contraction	Gja1	IMP	MGI:MGI:2386742,MGI:MGI:3051881	Mouse	PMID:11179202
Biological Process	GO:0008016	regulation of heart contraction	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:11397787
Biological Process	GO:0022898	regulation of transmembrane transporter activity	Gja1	IMP		Rat	PMID:15284189|RGD:12793029
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:10969038
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:9109444
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	Gja1	IGI	MGI:MGI:95716	Mouse	PMID:10969038
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	Gja1	IGI	MGI:MGI:95716	Mouse	PMID:10969038
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	Gja1	IMP	MGI:MGI:1857177	Mouse	PMID:10969038
Biological Process	GO:0032355	response to estradiol	Gja1	IEP		Rat	PMID:25798059|RGD:13592600
Biological Process	GO:0034405	response to fluid shear stress	Gja1	IEP		Rat	PMID:15558296|RGD:7207817
Biological Process	GO:0009749	response to glucose	Gja1	IEP		Rat	PMID:21567444|RGD:7364783
Biological Process	GO:0002931	response to ischemia	Gja1	IEP		Rat	PMID:24728265|RGD:11568671
Biological Process	GO:0032496	response to lipopolysaccharide	Gja1	IEP		Rat	PMID:10909894|RGD:11568670
Biological Process	GO:0043434	response to peptide hormone	Gja1	IEP		Rat	PMID:12700188|RGD:2304185
Biological Process	GO:0009268	response to pH	Gja1	IDA		Rat	PMID:14699011|RGD:1582694
Biological Process	GO:0032526	response to retinoic acid	Gja1	IEP		Rat	PMID:9570757|RGD:11568675
Biological Process	GO:0007165	signal transduction	GJA1	IDA		Human	PMID:1696265
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Gja1	IDA		Mouse	PMID:15601660
Biological Process	GO:0007283	spermatogenesis	Gja1	IMP		Mouse	MGI:MGI:3715585|PMID:17591950
Biological Process	GO:0007283	spermatogenesis	Gja1	IMP		Rat	PMID:26678449|RGD:11532443
Biological Process	GO:0042110	T cell activation	Gja1	IDA		Mouse	MGI:MGI:5301502|PMID:21844382
Biological Process	GO:0042098	T cell proliferation	Gja1	IMP		Mouse	MGI:MGI:6274954|PMID:26648560
Biological Process	GO:0055085	transmembrane transport	Gja1	IDA		Rat	PMID:15284189|RGD:12793029
Biological Process	GO:0055085	transmembrane transport	Gja1	IDA		Rat	PMID:24503060|RGD:8662428
Biological Process	GO:0010232	vascular transport	Gja1	IMP		Rat	PMID:16878174|RGD:1601341
Biological Process	GO:0042311	vasodilation	Gja1	IMP		Rat	PMID:15301736|RGD:7207818
Biological Process	GO:0042908	xenobiotic transport	Gja1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern