Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gja8

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GJA8
- Mouse genes Gja8
- Rat genes Gja8
- Zfish genes gja8a,gja8b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gja8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005243	gap junction channel activity	GJA8	IDA		Human	PMID:19756179
Molecular Function	GO:0005243	gap junction channel activity	Gja8	IDA		Rat	PMID:16123426\|RGD:1598965
Molecular Function	GO:0055077	gap junction hemi-channel activity	gja8b	IDA		Zfish	PMID:11376491
Molecular Function	GO:0042802	identical protein binding	Gja8	IPI	RGD:628890	Rat	PMID:16123426\|RGD:1598965
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:A0PK05	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:B2RUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O00124	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O00590	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O14493	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O14523	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O15427	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O43561-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O43934	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O60831	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O75396	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O75841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O95070	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:O95236-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P00519-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P02652	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P05090	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P11215	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P11686	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P13236	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P19397	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P21145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P24593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P26678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P29033	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P37268	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P43628	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P54315	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P55087	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P57103-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P61266	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:P78329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q02747	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q13183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q14162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q15436	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q16849-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q53FV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q5BJH2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q5BVD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q5J5C9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q5RI15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q5T1Q4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q69YG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q6PI78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q6UX40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q6ZP29-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q6ZP80	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q6ZSM3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q6ZSS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q7RTS6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q7RTY0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q7Z2K6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q86UF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q86VI4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q86WB7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q86YT5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8N2U9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8N357	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8N6F1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8N6S5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8N8N0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8NC01	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8NFJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8TDU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8TDV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8WW34-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q8WWP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q92504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q969I6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q96F15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q96G79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q96HR9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q96P65	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q99437	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q99726	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q99735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9BPV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9BQA9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9BRL7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9BTD3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9BU79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9BVK8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9BZJ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9C0I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9GZX9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9H0Q3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9H228	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9H5X1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NP94	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NPR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NUM3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NV29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NWC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NWF4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NWH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9NWW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9P0B6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9P0N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9UHJ9-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9UNK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9UPQ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJA8	IPI	UniProtKB:Q9Y5U4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gja8	IPI	RGD:2280	Rat	PMID:16123426\|RGD:1598965
Cellular Component	GO:0005922	connexin complex	GJA8	IDA		Human	PMID:19756179
Cellular Component	GO:0005922	connexin complex	Gja8	IDA		Rat	PMID:16123426\|RGD:1598965
Cellular Component	GO:0016020	membrane	Gja8	IDA		Rat	PMID:16192745\|RGD:1598964
Cellular Component	GO:0005886	plasma membrane	GJA8	IDA		Human	PMID:19756179
Cellular Component	GO:0005886	plasma membrane	GJA8	IDA		Human	PMID:26004348
Cellular Component	GO:0005886	plasma membrane	Gja8	IDA		Mouse	PMID:9620080
Biological Process	GO:0043010	camera-type eye development	Gja8	IMP	MGI:MGI:3052418	Mouse	PMID:15253273
Biological Process	GO:0043010	camera-type eye development	Gja8	IMP	MGI:MGI:2137525	Mouse	PMID:11782410
Biological Process	GO:0007267	cell-cell signaling	Gja8	IDA		Rat	PMID:16123426\|RGD:1598965
Biological Process	GO:1990349	gap junction-mediated intercellular transport	GJA8	IDA		Human	PMID:19756179
Biological Process	GO:0002088	lens development in camera-type eye	Gja8	IMP	MGI:MGI:1857499	Mouse	PMID:6877261
Biological Process	GO:1902551	regulation of catalase activity	Gja8	IMP		Rat	PMID:27871290\|RGD:150429989
Biological Process	GO:1903282	regulation of glutathione peroxidase activity	Gja8	IMP		Rat	PMID:27871290\|RGD:150429989
Biological Process	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	Gja8	IMP		Rat	PMID:27871290\|RGD:150429989

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.