Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GJB1
  • Mouse genes Gjb1
  • Rat genes Gjb1
  • Zfish genes gjb1a,gjb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gjb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005243	gap junction channel activity	Gjb1	IDA		Rat	PMID:12119284|RGD:728476
Molecular Function	GO:0042802	identical protein binding	Gjb1	IPI	PR:P28230	Mouse	PMID:20578039
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:A2A2V5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:A2RU14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O00155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O00767	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O14523	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O14735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O43561-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O75841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O95236-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P02787	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P11049	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P11215	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P15692-12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P21145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P29033	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P43378	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P48230	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P52803	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:P54852	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q07325	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q0D2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q5BVD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q5QGT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q6ZUX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q969L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q96MX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9BXN2-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9GZY8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9NX14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9P0S9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9UNK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9Y2Y6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9Y5U9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9Y666-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB1	IPI	UniProtKB:Q9Y6I9	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Gjb1	IDA		Mouse	PMID:20089884
Cellular Component	GO:0005921	gap junction	Gjb1	IDA		Mouse	PMID:20089884
Cellular Component	GO:0005921	gap junction	Gjb1	IDA		Rat	PMID:12119284|RGD:728476
Cellular Component	GO:0016328	lateral plasma membrane	Gjb1	IDA		Rat	PMID:12388089|RGD:628541
Cellular Component	GO:0005886	plasma membrane	Gjb1	IDA		Mouse	PMID:12829745
Cellular Component	GO:0005886	plasma membrane	Gjb1	IDA		Rat	PMID:15817491|RGD:1582686
Cellular Component	GO:0005886	plasma membrane	Gjb1	IDA		Rat	PMID:7762611|RGD:7349397
Cellular Component	GO:0032991	protein-containing complex	Gjb1	IDA		Rat	PMID:15817491|RGD:1582686
Biological Process	GO:1905867	epididymis development	Gjb1	IEP		Rat	PMID:12388089|RGD:628541
Biological Process	GO:0021782	glial cell development	gjb1b	IMP	ZFIN:ZDB-CRISPR-191009-31,ZFIN:ZDB-CRISPR-191009-32	Zfish	PMID:30924555
Biological Process	GO:0015868	purine ribonucleotide transport	Gjb1	IDA		Rat	PMID:12119284|RGD:728476
Biological Process	GO:0060041	retina development in camera-type eye	gjb1b	IMP	ZFIN:ZDB-CRISPR-191009-31,ZFIN:ZDB-CRISPR-191009-32	Zfish	PMID:30924555

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern