Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GLRA1
  • Mouse genes Glra1
  • Rat genes Glra1
  • Zfish genes glra1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Glra1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	GLRA1	IDA		Human	PMID:16144831
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	GLRA1	IDA		Human	PMID:2155780
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	GLRA1	IMP		Human	PMID:7920629
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	GLRA1	IDA		Human	PMID:8137830
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glra1	IMP		Mouse	MGI:MGI:5707576|PMID:24801766
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:16672662
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glra1	IDA		Mouse	PMID:8062927
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:16672662
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glra1	IDA		Rat	PMID:12223345|RGD:625689
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	glra1	IDA		Zfish	PMID:11274795
Molecular Function	GO:0016933	extracellularly glycine-gated ion channel activity	Glra1	IDA		Rat	PMID:15574743|RGD:1598572
Molecular Function	GO:0016933	extracellularly glycine-gated ion channel activity	glra1	IDA		Zfish	PMID:30323738
Molecular Function	GO:0016594	glycine binding	GLRA1	IDA		Human	PMID:15748848
Molecular Function	GO:0016594	glycine binding	GLRA1	IDA		Human	PMID:2155780
Molecular Function	GO:0016594	glycine binding	GLRA1	IDA		Human	PMID:7920629
Molecular Function	GO:0016594	glycine binding	GLRA1	IDA		Human	PMID:8717357
Molecular Function	GO:0016594	glycine binding	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:9145798
Molecular Function	GO:0016594	glycine binding	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:8062927
Molecular Function	GO:0016594	glycine binding	Glra1	IDA		Mouse	PMID:7874121
Molecular Function	GO:0016594	glycine binding	Glra1	IDA		Rat	PMID:15574743|RGD:1598572
Molecular Function	GO:0016594	glycine binding	glra1	IDA		Zfish	PMID:33617876
Molecular Function	GO:0016594	glycine binding	glra1	IDA		Zfish	PMID:26344198
Molecular Function	GO:0042802	identical protein binding	Glra1	IPI	RGD:2704	Rat	PMID:14749434|RGD:1598573
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	glra1	IDA		Zfish	PMID:33617876
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GLRA1	IDA		Human	PMID:8137830
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GLRA1	IMP		Human	PMID:8137830
Molecular Function	GO:0005515	protein binding	GLRA1	IPI	UniProtKB:P48167	Human	PMID:11929858
Molecular Function	GO:0005515	protein binding	GLRA1	IPI	UniProtKB:O60504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GLRA1	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0044877	protein-containing complex binding	Glra1	IDA		Rat	PMID:15574743|RGD:1598572
Molecular Function	GO:0030977	taurine binding	GLRA1	IDA		Human	PMID:15748848
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Glra1	IMP		Mouse	PMID:28724750
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Glra1	IDA		Mouse	PMID:28724750
Molecular Function	GO:0008270	zinc ion binding	GLRA1	IMP		Human	PMID:16144831
Cellular Component	GO:0044305	calyx of Held	Glra1	IDA		Rat	PMID:23175852|RGD:13702302
Cellular Component	GO:0005783	endoplasmic reticulum	Glra1	IDA		Rat	PMID:17145751|RGD:8554660
Cellular Component	GO:0009897	external side of plasma membrane	Glra1	IDA		Mouse	PMID:17145751
Cellular Component	GO:0009897	external side of plasma membrane	Glra1	IDA		Rat	PMID:17145751|RGD:8554660
Cellular Component	GO:0098690	glycinergic synapse	Glra1	IMP		Mouse	PMID:28724750
Cellular Component	GO:0098690	glycinergic synapse	Glra1	IDA		Mouse	PMID:28724750
Cellular Component	GO:0098690	glycinergic synapse	Glra1	IDA		Rat	PMID:25339867|RGD:13702401
Cellular Component	GO:0060077	inhibitory synapse	Glra1	IDA		Mouse	PMID:9812897
Cellular Component	GO:0005622	intracellular anatomical structure	Glra1	IDA		Mouse	PMID:17145751
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GLRA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GLRA1	IDA		Human	PMID:7506679
Cellular Component	GO:0016020	membrane	Glra1	IDA		Mouse	PMID:17114051
Cellular Component	GO:0016020	membrane	Glra1	IDA		Mouse	PMID:9145798
Cellular Component	GO:0016020	membrane	Glra1	IDA		Mouse	PMID:1371219
Cellular Component	GO:0016020	membrane	Glra1	IDA		Rat	PMID:17145751|RGD:8554660
Cellular Component	GO:0016020	membrane	glra1	IDA		Zfish	PMID:26344198
Cellular Component	GO:0043005	neuron projection	Glra1	IDA		Mouse	MGI:MGI:5707576|PMID:24801766
Cellular Component	GO:0043025	neuronal cell body	Glra1	IDA		Mouse	MGI:MGI:5707576|PMID:24801766
Cellular Component	GO:0005886	plasma membrane	GLRA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GLRA1	IMP		Human	PMID:11973623
Cellular Component	GO:0005886	plasma membrane	GLRA1	IDA		Human	PMID:16144831
Cellular Component	GO:0005886	plasma membrane	GLRA1	IDA		Human	PMID:2155780
Cellular Component	GO:0005886	plasma membrane	GLRA1	IDA		Human	PMID:7506679
Cellular Component	GO:0045211	postsynaptic membrane	Glra1	IDA		Mouse	PMID:17114051
Cellular Component	GO:0045211	postsynaptic membrane	Glra1	IDA		Mouse	PMID:16964444
Cellular Component	GO:0099634	postsynaptic specialization membrane	Glra1	IDA		Rat	PMID:25339867|RGD:13702401
Cellular Component	GO:0042734	presynaptic membrane	Glra1	IDA		Rat	PMID:23175852|RGD:13702302
Cellular Component	GO:0045202	synapse	Glra1	IDA		Mouse	MGI:MGI:5707576|PMID:24801766
Biological Process	GO:0007340	acrosome reaction	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:11076688
Biological Process	GO:0007628	adult walking behavior	Glra1	IMP	MGI:MGI:3696673	Mouse	PMID:17114051
Biological Process	GO:0071230	cellular response to amino acid stimulus	GLRA1	IDA		Human	PMID:16144831
Biological Process	GO:0071361	cellular response to ethanol	GLRA1	IDA		Human	PMID:25973519
Biological Process	GO:0071294	cellular response to zinc ion	GLRA1	IDA		Human	PMID:16144831
Biological Process	GO:0007417	central nervous system development	glra1	IMP	ZFIN:ZDB-MRPHLNO-060706-2	Zfish	PMID:16763051
Biological Process	GO:0007268	chemical synaptic transmission	Glra1	IDA		Mouse	MGI:MGI:6092912|PMID:28724750
Biological Process	GO:0007268	chemical synaptic transmission	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:12837931
Biological Process	GO:0007268	chemical synaptic transmission	Glra1	IMP	MGI:MGI:1856363	Mouse	PMID:12837931
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Glra1	IDA		Mouse	MGI:MGI:6092912|PMID:28724750
Biological Process	GO:1902476	chloride transmembrane transport	GLRA1	IDA		Human	PMID:16144831
Biological Process	GO:0006821	chloride transport	GLRA1	IDA		Human	PMID:8137830
Biological Process	GO:0006821	chloride transport	Glra1	IDA		Rat	PMID:1703526|RGD:728781
Biological Process	GO:0060079	excitatory postsynaptic potential	glra1	IDA		Zfish	PMID:30323738|ZFIN:ZDB-PUB-181017-7
Biological Process	GO:0060080	inhibitory postsynaptic potential	Glra1	IMP		Mouse	MGI:MGI:5707576|PMID:24801766
Biological Process	GO:0060080	inhibitory postsynaptic potential	Glra1	IMP	MGI:MGI:3696673	Mouse	PMID:17114051
Biological Process	GO:0006820	monoatomic anion transport	Glra1	IDA		Rat	PMID:12223345|RGD:625689
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Glra1	IDA		Mouse	MGI:MGI:6092912|PMID:28724750
Biological Process	GO:0034220	monoatomic ion transmembrane transport	glra1	IDA		Zfish	PMID:30323738|ZFIN:ZDB-PUB-181017-7
Biological Process	GO:0006811	monoatomic ion transport	GLRA1	IDA		Human	PMID:2155780
Biological Process	GO:0006811	monoatomic ion transport	glra1	IDA		Zfish	PMID:10188956
Biological Process	GO:0006936	muscle contraction	GLRA1	IMP		Human	PMID:11973623
Biological Process	GO:0051970	negative regulation of transmission of nerve impulse	GLRA1	IMP		Human	PMID:11973623
Biological Process	GO:0050905	neuromuscular process	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:9087981
Biological Process	GO:0050905	neuromuscular process	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:9087981
Biological Process	GO:0050905	neuromuscular process	Glra1	IMP	MGI:MGI:3696673	Mouse	PMID:17114051
Biological Process	GO:0050884	neuromuscular process controlling posture	Glra1	IMP	MGI:MGI:3696673	Mouse	PMID:17114051
Biological Process	GO:0019228	neuronal action potential	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:11742725
Biological Process	GO:0019228	neuronal action potential	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:16800867
Biological Process	GO:0007218	neuropeptide signaling pathway	GLRA1	IDA		Human	PMID:2155780
Biological Process	GO:2000344	positive regulation of acrosome reaction	GLRA1	IMP		Human	PMID:11751269
Biological Process	GO:0042391	regulation of membrane potential	GLRA1	IMP		Human	PMID:7920629
Biological Process	GO:0042391	regulation of membrane potential	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:16672662
Biological Process	GO:0042391	regulation of membrane potential	Glra1	IDA		Mouse	PMID:8062927
Biological Process	GO:0042391	regulation of membrane potential	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:16672662
Biological Process	GO:0045664	regulation of neuron differentiation	glra1	IMP	ZFIN:ZDB-MRPHLNO-060706-2	Zfish	PMID:16763051
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Glra1	IDA		Mouse	MGI:MGI:6092912|PMID:28724750
Biological Process	GO:0043576	regulation of respiratory gaseous exchange	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:12380014
Biological Process	GO:0043576	regulation of respiratory gaseous exchange	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:11742725
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:16800867
Biological Process	GO:0097305	response to alcohol	Glra1	IMP		Mouse	MGI:MGI:5707576|PMID:24801766
Biological Process	GO:0043200	response to amino acid	glra1	IDA		Zfish	PMID:10188956
Biological Process	GO:0060013	righting reflex	Glra1	IMP	MGI:MGI:3696673	Mouse	PMID:17114051
Biological Process	GO:0001964	startle response	GLRA1	IMP		Human	PMID:8298642
Biological Process	GO:0001964	startle response	GLRA1	IMP		Human	PMID:11973623
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:8406478
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:12380014
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:9087981
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:2429918	Mouse	PMID:16964444
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:9087981
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:3696673	Mouse	PMID:17114051
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:11275284
Biological Process	GO:0001964	startle response	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:8733750
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glra1	IMP		Mouse	MGI:MGI:5707576|PMID:24801766
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glra1	IMP	MGI:MGI:1856177	Mouse	PMID:16672662
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glra1	IMP	MGI:MGI:1856362	Mouse	PMID:16672662
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glra1	IDA		Rat	PMID:15574743|RGD:1598572
Biological Process	GO:0007601	visual perception	Glra1	IMP	MGI:MGI:3696673	Mouse	PMID:17114051

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern