Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GLRA2
  • Mouse genes Glra2
  • Rat genes Glra2
  • Zfish genes glra2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Glra2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	GLRA2	IDA		Human	PMID:2155780
Molecular Function	GO:0016933	extracellularly glycine-gated ion channel activity	glra2	IDA		Zfish	PMID:30323738
Molecular Function	GO:0016594	glycine binding	GLRA2	IDA		Human	PMID:2155780
Molecular Function	GO:0022852	glycine-gated chloride ion channel activity	GLRA2	IDA		Human	PMID:23895467
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Glra2	IMP		Mouse	PMID:19528249
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Glra2	IDA		Mouse	PMID:19528249
Cellular Component	GO:0098690	glycinergic synapse	Glra2	IDA		Mouse	PMID:19528249
Cellular Component	GO:0098690	glycinergic synapse	Glra2	IMP		Mouse	PMID:19528249
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GLRA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GLRA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GLRA2	IDA		Human	PMID:2155780
Cellular Component	GO:0005886	plasma membrane	GLRA2	IDA		Human	PMID:23895467
Biological Process	GO:0071230	cellular response to amino acid stimulus	GLRA2	IDA		Human	PMID:2155780
Biological Process	GO:0071361	cellular response to ethanol	GLRA2	IDA		Human	PMID:23895467
Biological Process	GO:0071294	cellular response to zinc ion	GLRA2	IDA		Human	PMID:23895467
Biological Process	GO:1902476	chloride transmembrane transport	GLRA2	IDA		Human	PMID:23895467
Biological Process	GO:0060079	excitatory postsynaptic potential	glra2	IDA		Zfish	PMID:30323738|ZFIN:ZDB-PUB-181017-7
Biological Process	GO:0034220	monoatomic ion transmembrane transport	GLRA2	IDA		Human	PMID:2155780
Biological Process	GO:0034220	monoatomic ion transmembrane transport	glra2	IDA		Zfish	PMID:30323738|ZFIN:ZDB-PUB-181017-7
Biological Process	GO:0007218	neuropeptide signaling pathway	GLRA2	IDA		Human	PMID:2155780
Biological Process	GO:0021510	spinal cord development	Glra2	IEP		Rat	PMID:12124753|RGD:708602
Biological Process	GO:0007416	synapse assembly	Glra2	IEP		Rat	PMID:1645300|RGD:728718

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern