Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GLRA3
  • Mouse genes Glra3
  • Rat genes Glra3
  • Zfish genes glra3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Glra3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	GLRA3	IDA		Human	PMID:26416729
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glra3	IDA		Rat	PMID:2176214|RGD:728440
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glra3	IDA		Rat	PMID:23895467|RGD:11035333
Molecular Function	GO:0016933	extracellularly glycine-gated ion channel activity	glra3	IDA		Zfish	PMID:30323738
Molecular Function	GO:0022852	glycine-gated chloride ion channel activity	GLRA3	IDA		Human	PMID:9677400
Cellular Component	GO:0016935	glycine-gated chloride channel complex	GLRA3	IDA		Human	PMID:9677400
Cellular Component	GO:0098690	glycinergic synapse	Glra3	IDA		Mouse	PMID:26851771
Cellular Component	GO:0098690	glycinergic synapse	Glra3	IMP		Mouse	PMID:26851771
Cellular Component	GO:0098690	glycinergic synapse	Glra3	IDA		Rat	PMID:22574341|RGD:13702330
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GLRA3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GLRA3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GLRA3	IDA		Human	PMID:26416729
Cellular Component	GO:0005886	plasma membrane	GLRA3	IMP		Human	PMID:9677400
Cellular Component	GO:0005886	plasma membrane	Glra3	IDA		Rat	PMID:23895467|RGD:11035333
Cellular Component	GO:0099634	postsynaptic specialization membrane	Glra3	IDA		Rat	PMID:22574341|RGD:13702330
Cellular Component	GO:0098793	presynapse	Glra3	IMP		Mouse	MGI:MGI:5770489|PMID:26851771
Cellular Component	GO:0042734	presynaptic membrane	Glra3	IMP		Mouse	PMID:26851771
Cellular Component	GO:0042734	presynaptic membrane	Glra3	IDA		Mouse	PMID:26851771
Biological Process	GO:0071230	cellular response to amino acid stimulus	Glra3	IDA		Rat	PMID:23895467|RGD:11035333
Biological Process	GO:0071361	cellular response to ethanol	Glra3	IDA		Rat	PMID:23895467|RGD:11035333
Biological Process	GO:0071294	cellular response to zinc ion	Glra3	IDA		Rat	PMID:23895467|RGD:11035333
Biological Process	GO:1902476	chloride transmembrane transport	GLRA3	IDA		Human	PMID:9677400
Biological Process	GO:1902476	chloride transmembrane transport	Glra3	IDA		Rat	PMID:23895467|RGD:11035333
Biological Process	GO:0060079	excitatory postsynaptic potential	glra3	IDA		Zfish	PMID:30323738|ZFIN:ZDB-PUB-181017-7
Biological Process	GO:0034220	monoatomic ion transmembrane transport	glra3	IDA		Zfish	PMID:30323738|ZFIN:ZDB-PUB-181017-7
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Glra3	IMP		Mouse	PMID:26851771
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Glra3	IDA		Mouse	PMID:26851771
Biological Process	GO:0051260	protein homooligomerization	GLRA3	IDA		Human	PMID:26416729

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern