Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GLRB
  • Mouse genes Glrb
  • Rat genes Glrb
  • Zfish genes glrba,glrbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Glrb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	GLRB	IDA		Human	PMID:8717357
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:12809985
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:16672662
Molecular Function	GO:0016934	extracellularly glycine-gated chloride channel activity	glrbb	IMP	ZFIN:ZDB-GENO-980202-835	Zfish	PMID:15928085
Molecular Function	GO:0016933	extracellularly glycine-gated ion channel activity	GLRB	IMP		Human	PMID:11929858
Molecular Function	GO:0016933	extracellularly glycine-gated ion channel activity	Glrb	IDA		Rat	PMID:15574743|RGD:1598572
Molecular Function	GO:0016594	glycine binding	GLRB	IMP		Human	PMID:15748848
Molecular Function	GO:0016594	glycine binding	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:6285205
Molecular Function	GO:0016594	glycine binding	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:2983837
Molecular Function	GO:0016594	glycine binding	Glrb	IDA		Rat	PMID:15574743|RGD:1598572
Molecular Function	GO:0005515	protein binding	GLRB	IPI	UniProtKB:P23415	Human	PMID:11929858
Molecular Function	GO:0005515	protein binding	GLRB	IPI	UniProtKB:Q03555	Human	PMID:15215304
Molecular Function	GO:0005515	protein binding	GLRB	IPI	UniProtKB:Q9NQX3	Human	PMID:26613940
Molecular Function	GO:0005515	protein binding	Glrb	IPI	UniProtKB:Q8BUV3	Mouse	MGI:MGI:3714566|PMID:17347650
Molecular Function	GO:0005515	protein binding	Glrb	IPI	UniProtKB:Q03555|UniProtKB:Q8BUV3	Mouse	MGI:MGI:5304639|PMID:21829170
Molecular Function	GO:0005515	protein binding	Glrb	IPI	RGD:69194	Rat	PMID:14976213|RGD:1300220
Molecular Function	GO:0044877	protein-containing complex binding	Glrb	IDA		Rat	PMID:15574743|RGD:1598572
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Glrb	IMP		Mouse	PMID:16672662
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Glrb	IDA		Mouse	PMID:16672662
Cellular Component	GO:0030425	dendrite	Glrb	IDA		Mouse	PMID:19723286
Cellular Component	GO:0098982	GABA-ergic synapse	Glrb	IDA		Mouse	PMID:19723286
Cellular Component	GO:0016935	glycine-gated chloride channel complex	GLRB	IDA		Human	PMID:11929858
Cellular Component	GO:0098690	glycinergic synapse	Glrb	IDA		Mouse	PMID:16672662
Cellular Component	GO:0098690	glycinergic synapse	Glrb	IMP		Mouse	PMID:16672662
Cellular Component	GO:0098690	glycinergic synapse	Glrb	IDA		Rat	PMID:22592841|RGD:13702311
Cellular Component	GO:0016020	membrane	Glrb	IDA		Mouse	PMID:17145751
Cellular Component	GO:0005886	plasma membrane	GLRB	IMP		Human	PMID:11929858
Cellular Component	GO:0005886	plasma membrane	GLRB	IDA		Human	PMID:8717357
Cellular Component	GO:0099572	postsynaptic specialization	Glrb	IDA		Rat	PMID:22592841|RGD:13702311
Biological Process	GO:0007340	acrosome reaction	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:11076688
Biological Process	GO:0007628	adult walking behavior	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:4323808
Biological Process	GO:0007268	chemical synaptic transmission	GLRB	IMP		Human	PMID:11929858
Biological Process	GO:0007268	chemical synaptic transmission	Glrb	IMP		Mouse	MGI:MGI:3623689|PMID:16672662
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Glrb	IMP		Mouse	MGI:MGI:3623689|PMID:16672662
Biological Process	GO:1902476	chloride transmembrane transport	GLRB	IMP		Human	PMID:11929858
Biological Process	GO:0097112	gamma-aminobutyric acid receptor clustering	Glrb	IGI	MGI:MGI:95749	Mouse	PMID:19723286
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Glrb	IMP		Mouse	MGI:MGI:3623689|PMID:16672662
Biological Process	GO:0006811	monoatomic ion transport	GLRB	IDA		Human	PMID:8717357
Biological Process	GO:0007399	nervous system development	GLRB	IMP		Human	PMID:11929858
Biological Process	GO:0050905	neuromuscular process	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:9087981
Biological Process	GO:0050905	neuromuscular process	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:8635460
Biological Process	GO:0050905	neuromuscular process	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:10651857
Biological Process	GO:0007218	neuropeptide signaling pathway	GLRB	IDA		Human	PMID:8717357
Biological Process	GO:0008104	protein localization	glrbb	IMP	ZFIN:ZDB-GENO-980202-835	Zfish	PMID:15928085
Biological Process	GO:0042391	regulation of membrane potential	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:16672662
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Glrb	IMP		Mouse	MGI:MGI:3623689|PMID:16672662
Biological Process	GO:0060013	righting reflex	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:6285205
Biological Process	GO:0001964	startle response	GLRB	IMP		Human	PMID:11929858
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:12809985
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:16672662
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glrb	IMP		Mouse	PMID:1338094
Biological Process	GO:0060012	synaptic transmission, glycinergic	Glrb	IDA		Rat	PMID:15574743|RGD:1598572
Biological Process	GO:0007601	visual perception	Glrb	IMP	MGI:MGI:1856363	Mouse	PMID:1338094

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern