Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNAI3
  • Mouse genes Gnai3
  • Rat genes Gnai3
  • Zfish genes gnai3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnai3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031821	G protein-coupled serotonin receptor binding	Gnai3	IPI	RGD:2845	Rat	PMID:16772521|RGD:2303642
Molecular Function	GO:0019003	GDP binding	GNAI3	IDA		Human	PMID:19478087
Molecular Function	GO:0032794	GTPase activating protein binding	Gnai3	IPI	RGD:3564	Rat	PMID:11387333|RGD:7207387
Molecular Function	GO:0032794	GTPase activating protein binding	Gnai3	IPI	RGD:620003	Rat	PMID:11387333|RGD:7207387
Molecular Function	GO:0003924	GTPase activity	GNAI3	IDA		Human	PMID:19478087
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:O43665	Human	PMID:18434541
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:O43566	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q9UGC6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q9Y4H4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q9P219	Human	PMID:26126266
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q3V6T2	Human	PMID:27621449
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q8IVA1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q9BRC7-1	Human	PMID:30194280
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q9BRC7-2	Human	PMID:30194280
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:O43566	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:P81274	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q8IVA1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q9UPV7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNAI3	IPI	UniProtKB:Q9Y4H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:P09405	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	PR:Q80TL4	Mouse	PMID:25242222
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:O08773	Rat	PMID:11387333|RGD:7207387
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:O08774	Rat	PMID:11387333|RGD:7207387
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	RGD:727957	Rat	PMID:12509430|RGD:633903
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:Q5BJU7	Rat	PMID:16530190|RGD:8554036
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:O08773	Rat	PMID:16870394|RGD:8553973
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:Q3V6T2	Rat	PMID:19211784|RGD:15023483
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:Q3V6T2	Rat	PMID:23509302|RGD:15023471
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:Q3V6T2	Rat	PMID:27621449|RGD:15023482
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	UniProtKB:P49795	Rat	PMID:8524874|RGD:8554525
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	RGD:629471	Rat	PMID:8986788|RGD:4892327
Molecular Function	GO:0005515	protein binding	Gnai3	IPI	RGD:3239	Rat	PMID:9176188|RGD:4890391
Molecular Function	GO:0019904	protein domain specific binding	Gnai3	IPI	RGD:3564	Rat	PMID:11387333|RGD:7207387
Molecular Function	GO:0019904	protein domain specific binding	Gnai3	IPI	RGD:620003	Rat	PMID:11387333|RGD:7207387
Cellular Component	GO:0005813	centrosome	GNAI3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	GNAI3	IDA		Human	PMID:17635935
Cellular Component	GO:0005737	cytoplasm	GNAI3	IDA		Human	PMID:17635935
Cellular Component	GO:0005737	cytoplasm	Gnai3	IDA		Mouse	PMID:8192889
Cellular Component	GO:0005789	endoplasmic reticulum membrane	GNAI3	IDA		Human	PMID:12642577
Cellular Component	GO:0070062	extracellular exosome	GNAI3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GNAI3	HDA		Human	PMID:20458337
Cellular Component	GO:0005794	Golgi apparatus	Gnai3	IDA		Mouse	PMID:8192889
Cellular Component	GO:0000139	Golgi membrane	GNAI3	IDA		Human	PMID:12642577
Cellular Component	GO:0005765	lysosomal membrane	GNAI3	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	GNAI3	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Gnai3	IDA		Rat	PMID:15961389|RGD:1598749
Cellular Component	GO:0016020	membrane	Gnai3	IDA		Rat	PMID:16741924|RGD:2312769
Cellular Component	GO:0045121	membrane raft	Gnai3	IDA		Rat	PMID:17157995|RGD:1625132
Cellular Component	GO:0030496	midbody	GNAI3	IDA		Human	PMID:17635935
Cellular Component	GO:0005730	nucleolus	GNAI3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	GNAI3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GNAI3	IDA		Human	PMID:17635935
Cellular Component	GO:0005886	plasma membrane	GNAI3	IDA		Human	PMID:27864364
Cellular Component	GO:0005886	plasma membrane	Gnai3	IDA		Rat	PMID:11387333|RGD:7207387
Cellular Component	GO:0042588	zymogen granule	Gnai3	IDA		Rat	PMID:12038977|RGD:728690
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GNAI3	IDA		Human	PMID:19478087
Biological Process	GO:0007420	brain development	Gnai3	IEP		Rat	PMID:11850064|RGD:13508595
Biological Process	GO:0051301	cell division	GNAI3	IDA		Human	PMID:17635935
Biological Process	GO:0007212	dopamine receptor signaling pathway	GNAI3	IDA		Human	PMID:19478087
Biological Process	GO:0046039	GTP metabolic process	GNAI3	IDA		Human	PMID:19478087
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Gnai3	IMP		Rat	PMID:25633408|RGD:13507311
Biological Process	GO:0016239	positive regulation of macroautophagy	GNAI3	IMP		Human	PMID:12642577
Biological Process	GO:0033864	positive regulation of NAD(P)H oxidase activity	Gnai3	IMP		Rat	PMID:27912212|RGD:13507308
Biological Process	GO:0032930	positive regulation of superoxide anion generation	Gnai3	IMP		Rat	PMID:27912212|RGD:13507308
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	Gnai3	IMP		Rat	PMID:27912212|RGD:13507308
Biological Process	GO:0006906	vesicle fusion	Gnai3	IDA		Rat	PMID:12038977|RGD:728690

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern