Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gnao1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GNAO1
- Mouse genes Gnao1
- Rat genes Gnao1
- Zfish genes gnao1a,gnao1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnao1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051430	corticotropin-releasing hormone receptor 1 binding	Gnao1	IPI	RGD:61276	Rat	PMID:20548297\|RGD:5491170
Molecular Function	GO:0031821	G protein-coupled serotonin receptor binding	Gnao1	IPI	RGD:2845	Rat	PMID:16772521\|RGD:2303642
Molecular Function	GO:0005525	GTP binding	Gnao1	IMP	MGI:MGI:2152685	Mouse	PMID:11248120
Molecular Function	GO:0005525	GTP binding	Gnao1	IDA		Rat	PMID:11100733\|RGD:2302004
Molecular Function	GO:0032794	GTPase activating protein binding	Gnao1	IPI	RGD:3567	Rat	PMID:20530129\|RGD:7207369
Molecular Function	GO:0003924	GTPase activity	Gnao1	IDA		Mouse	MGI:MGI:5009199\|PMID:10926822
Molecular Function	GO:0003924	GTPase activity	Gnao1	IDA		Rat	PMID:20530129\|RGD:7207369
Molecular Function	GO:0031852	mu-type opioid receptor binding	Gnao1	IPI	RGD:3234	Rat	PMID:18384820\|RGD:2301996
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P27797	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P28288-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P36957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P45973	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P51812	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P55072	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:Q8TDX7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GNAO1	IPI	UniProtKB:P49795	Human	PMID:34685729
Molecular Function	GO:0005515	protein binding	Gnao1	IPI	UniProtKB:P97428	Mouse	MGI:MGI:6092643\|PMID:18434540
Molecular Function	GO:0005515	protein binding	Gnao1	IPI	UniProtKB:P97492	Mouse	MGI:MGI:5009199\|PMID:10926822
Molecular Function	GO:0005515	protein binding	Gnao1	IPI	RGD:3570	Rat	PMID:10092682\|RGD:69962
Molecular Function	GO:0005515	protein binding	Gnao1	IPI	RGD:727957	Rat	PMID:12509430\|RGD:633903
Molecular Function	GO:0005515	protein binding	Gnao1	IPI	UniProtKB:P17612	Rat	PMID:17148597\|RGD:13432337
Molecular Function	GO:0005515	protein binding	Gnao1	IPI	UniProtKB:Q9NS28	Rat	PMID:21685921\|RGD:13432351
Molecular Function	GO:0005515	protein binding	Gnao1	IPI	UniProtKB:P49804	Rat	PMID:9394004\|RGD:69963
Molecular Function	GO:0005102	signaling receptor binding	Gnao1	IPI	RGD:620768	Rat	PMID:9261169\|RGD:632421
Cellular Component	GO:0044297	cell body	Gnao1	IDA		Mouse	PMID:11685543
Cellular Component	GO:0030425	dendrite	Gnao1	IDA		Mouse	PMID:12454992
Cellular Component	GO:0030425	dendrite	Gnao1	IDA		Mouse	PMID:11685543
Cellular Component	GO:0016020	membrane	Gnao1	IDA		Rat	PMID:10212487\|RGD:2302006
Cellular Component	GO:0043209	myelin sheath	Gnao1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0043209	myelin sheath	Gnao1	IDA		Rat	PMID:17960831\|RGD:10047364
Cellular Component	GO:0043005	neuron projection	Gnao1	IDA		Rat	PMID:18384820\|RGD:2301996
Cellular Component	GO:0005886	plasma membrane	GNAO1	IDA		Human	PMID:34685729
Biological Process	GO:0007568	aging	Gnao1	IDA		Rat	PMID:9400388\|RGD:2302009
Biological Process	GO:0007212	dopamine receptor signaling pathway	Gnao1	IMP	MGI:MGI:2152685	Mouse	PMID:11248120
Biological Process	GO:0030900	forebrain development	Gnao1	IEP		Rat	PMID:8746812\|RGD:2302010
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gnao1	IMP	MGI:MGI:2152685	Mouse	PMID:9501252
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gnao1	IMP		Rat	PMID:18162464\|RGD:2301999
Biological Process	GO:0007626	locomotory behavior	Gnao1	IMP	MGI:MGI:2152685	Mouse	PMID:9501252
Biological Process	GO:0051926	negative regulation of calcium ion transport	Gnao1	IMP		Rat	PMID:7932231\|RGD:2302013
Biological Process	GO:0046676	negative regulation of insulin secretion	Gnao1	IMP	MGI:MGI:4941848	Mouse	PMID:20622165
Biological Process	GO:0031175	neuron projection development	Gnao1	IEP		Rat	PMID:7493405\|RGD:2302011
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Gnao1	IEP		Rat	PMID:28706494\|RGD:13513970
Biological Process	GO:0043547	positive regulation of GTPase activity	Gnao1	IMP		Rat	PMID:7544301\|RGD:2302012
Biological Process	GO:0008016	regulation of heart contraction	Gnao1	IMP	MGI:MGI:2152683	Mouse	PMID:9050846
Biological Process	GO:0034097	response to cytokine	Gnao1	IEP		Rat	PMID:9685638\|RGD:2302008
Biological Process	GO:0042542	response to hydrogen peroxide	Gnao1	IEP		Rat	PMID:11100733\|RGD:2302004
Biological Process	GO:0043278	response to morphine	Gnao1	IEP		Rat	PMID:8458398\|RGD:2302014
Biological Process	GO:0014070	response to organic cyclic compound	Gnao1	IEP		Rat	PMID:18384820\|RGD:2301996
Biological Process	GO:0010243	response to organonitrogen compound	Gnao1	IDA		Rat	PMID:9732414\|RGD:2302007
Biological Process	GO:0009410	response to xenobiotic stimulus	Gnao1	IEP		Rat	PMID:12199159\|RGD:2302002
Biological Process	GO:0006904	vesicle docking involved in exocytosis	Gnao1	IMP	MGI:MGI:4941848	Mouse	PMID:20622165

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.