Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNAZ
  • Mouse genes Gnaz
  • Rat genes Gnaz
  • Zfish genes gnaz
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnaz

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0010855	adenylate cyclase inhibitor activity	Gnaz	IMP	MGI:MGI:3575007	Mouse	PMID:18096703
Molecular Function	GO:0031821	G protein-coupled serotonin receptor binding	Gnaz	IPI	RGD:2845	Rat	PMID:16772521|RGD:2303642
Molecular Function	GO:0005515	protein binding	GNAZ	IPI	UniProtKB:O60241	Human	PMID:28891236
Cellular Component	GO:0044297	cell body	Gnaz	IDA		Mouse	PMID:11685543
Cellular Component	GO:0005829	cytosol	Gnaz	IDA		Rat	PMID:14534355|RGD:1601365
Cellular Component	GO:0005829	cytosol	Gnaz	IDA		Rat	PMID:15175423|RGD:5133684
Cellular Component	GO:0030425	dendrite	Gnaz	IDA		Mouse	PMID:11685543
Cellular Component	GO:0005886	plasma membrane	Gnaz	IDA		Mouse	PMID:21220323
Cellular Component	GO:0005886	plasma membrane	Gnaz	IDA		Rat	PMID:14534355|RGD:1601365
Cellular Component	GO:0005886	plasma membrane	Gnaz	IDA		Rat	PMID:15175423|RGD:5133684
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Gnaz	IMP		Rat	PMID:16157560|RGD:1578519
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Gnaz	IMP		Rat	PMID:15919662|RGD:1578518
Biological Process	GO:0098664	G protein-coupled serotonin receptor signaling pathway	Gnaz	IMP	MGI:MGI:3575007	Mouse	PMID:15931062
Biological Process	GO:0046676	negative regulation of insulin secretion	Gnaz	IMP	MGI:MGI:3575007	Mouse	PMID:18096703

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern