Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNB5
  • Mouse genes Gnb5
  • Rat genes Gnb5
  • Zfish genes gnb5a,gnb5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnb5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031682	G-protein gamma-subunit binding	GNB5	IPI	UniProtKB:P59768	Human	PMID:12606627
Molecular Function	GO:0031682	G-protein gamma-subunit binding	GNB5	IPI	UniProtKB:Q9P2W3	Human	PMID:12606627
Molecular Function	GO:0032794	GTPase activating protein binding	Gnb5	IPI	RGD:3570	Rat	PMID:10840031|RGD:6893668
Molecular Function	GO:0005096	GTPase activator activity	GNB5	IDA		Human	PMID:27677260
Molecular Function	GO:0005096	GTPase activator activity	GNB5	IDA		Human	PMID:10521509
Molecular Function	GO:0005515	protein binding	GNB5	IPI	UniProtKB:O94810	Human	PMID:12606627
Molecular Function	GO:0005515	protein binding	GNB5	IPI	UniProtKB:P49802	Human	PMID:19376773
Molecular Function	GO:0005515	protein binding	Gnb5	IPI	PR:O54828-2	Mouse	PMID:23555598
Molecular Function	GO:0005515	protein binding	Gnb5	IPI	PR:Q8BQP9	Mouse	PMID:15897264
Molecular Function	GO:0051087	protein-folding chaperone binding	GNB5	IPI	UniProtKB:P48643	Human	PMID:19376773
Cellular Component	GO:0044297	cell body	Gnb5	IDA		Rat	PMID:9648884|RGD:6893645
Cellular Component	GO:0005829	cytosol	GNB5	IDA		Human	PMID:10521509
Cellular Component	GO:0005829	cytosol	Gnb5	IDA		Rat	PMID:10840031|RGD:6893668
Cellular Component	GO:0043209	myelin sheath	Gnb5	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005634	nucleus	Gnb5	IDA		Mouse	PMID:15897264
Cellular Component	GO:0005886	plasma membrane	Gnb5	IDA		Mouse	PMID:15897264
Cellular Component	GO:0098793	presynapse	Gnb5	IDA		Mouse	PMID:27965545
Cellular Component	GO:0032991	protein-containing complex	Gnb5	IDA		Rat	PMID:10840031|RGD:6893668
Biological Process	GO:1990603	dark adaptation	Gnb5	IDA		Mouse	PMID:23555598
Biological Process	GO:0007212	dopamine receptor signaling pathway	GNB5	IDA		Human	PMID:27677260
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gnb5	IDA		Mouse	PMID:15897264
Biological Process	GO:0060047	heart contraction	gnb5a	IGI	ZFIN:ZDB-GENO-161202-14	Zfish	PMID:27523599
Biological Process	GO:0036367	light adaption	Gnb5	IDA		Mouse	PMID:23555598
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	GNB5	IDA		Human	PMID:11007869
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	GNB5	IDA		Human	PMID:12606627
Biological Process	GO:0007634	optokinetic behavior	gnb5a	IGI	ZFIN:ZDB-GENO-161202-14	Zfish	PMID:27523599
Biological Process	GO:0043547	positive regulation of GTPase activity	GNB5	IDA		Human	PMID:10521509
Biological Process	GO:0036269	swimming behavior	gnb5a	IGI	ZFIN:ZDB-GENO-161202-14	Zfish	PMID:27523599

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern