Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNG12
  • Mouse genes Gng12
  • Rat genes Gng12
  • Zfish genes gng12a,gng12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gng12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	GNG12	IDA		Human	PMID:23209302
Molecular Function	GO:0042301	phosphate ion binding	Gng12	IDA		Rat	PMID:9492299|RGD:2314449
Molecular Function	GO:0005515	protein binding	GNG12	IPI	UniProtKB:Q14192	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	GNG12	IPI	UniProtKB:Q14192	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GNG12	IPI	UniProtKB:Q14192	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GNG12	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNG12	IPI	UniProtKB:Q8WUI4-6	Human	PMID:32296183
Cellular Component	GO:0005884	actin filament	Gng12	IDA		Rat	PMID:9492299|RGD:2314449
Cellular Component	GO:0070062	extracellular exosome	GNG12	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GNG12	HDA		Human	PMID:23533145
Biological Process	GO:0021987	cerebral cortex development	Gng12	IEP		Rat	PMID:9003074|RGD:2314446
Biological Process	GO:0032496	response to lipopolysaccharide	Gng12	IEP		Rat	PMID:19568691|RGD:2314443

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern