Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNG2
  • Mouse genes Gng2
  • Rat genes
  • Zfish genes gng2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gng2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031681	G-protein beta-subunit binding	GNG2	IPI	UniProtKB:O14775	Human	PMID:12606627
Molecular Function	GO:0005515	protein binding	GNG2	IPI	UniProtKB:P62873	Human	PMID:23739333
Molecular Function	GO:0005515	protein binding	GNG2	IPI	UniProtKB:P62879	Human	PMID:28219978
Molecular Function	GO:0005515	protein binding	GNG2	IPI	UniProtKB:P62873	Human	PMID:32528175
Cellular Component	GO:0005829	cytosol	gng2	IDA		Zfish	PMID:19786091
Cellular Component	GO:0070062	extracellular exosome	GNG2	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	gng2	IDA		Zfish	PMID:19786091
Biological Process	GO:0048144	fibroblast proliferation	Gng2	IDA		Mouse	PMID:14712229
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gng2	IDA		Mouse	PMID:14712229
Biological Process	GO:0002040	sprouting angiogenesis	gng2	IGI	ZFIN:ZDB-MRPHLNO-050513-12,ZFIN:ZDB-MRPHLNO-060802-1	Zfish	PMID:16537812
Biological Process	GO:0002040	sprouting angiogenesis	gng2	IGI	ZFIN:ZDB-GENE-990415-273,ZFIN:ZDB-MRPHLNO-060802-1	Zfish	PMID:16537812
Biological Process	GO:0002040	sprouting angiogenesis	gng2	IMP	ZFIN:ZDB-MRPHLNO-060802-1	Zfish	PMID:16537812
Biological Process	GO:0002040	sprouting angiogenesis	gng2	IMP	ZFIN:ZDB-MRPHLNO-060802-2	Zfish	PMID:16537812
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	gng2	IGI	ZFIN:ZDB-GENE-990415-273,ZFIN:ZDB-MRPHLNO-060802-1	Zfish	PMID:16537812

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern