Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNMT
  • Mouse genes Gnmt
  • Rat genes Gnmt
  • Zfish genes gnmt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005542	folic acid binding	Gnmt	IDA		Rat	PMID:17158459|RGD:7242951
Molecular Function	GO:0005542	folic acid binding	Gnmt	IDA		Rat	PMID:22037183|RGD:151356643
Molecular Function	GO:0016594	glycine binding	GNMT	IDA		Human	PMID:15340920
Molecular Function	GO:0016594	glycine binding	Gnmt	IDA		Mouse	MGI:MGI:3852308|PMID:15340920
Molecular Function	GO:0016594	glycine binding	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Molecular Function	GO:0016594	glycine binding	Gnmt	IDA		Rat	PMID:15340920|RGD:8553948
Molecular Function	GO:0017174	glycine N-methyltransferase activity	GNMT	IDA		Human	PMID:15340920
Molecular Function	GO:0017174	glycine N-methyltransferase activity	Gnmt	IDA		Mouse	MGI:MGI:3852308|PMID:15340920
Molecular Function	GO:0017174	glycine N-methyltransferase activity	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Molecular Function	GO:0017174	glycine N-methyltransferase activity	Gnmt	IDA		Rat	PMID:12054489|RGD:728472
Molecular Function	GO:0017174	glycine N-methyltransferase activity	Gnmt	IDA		Rat	PMID:15340920|RGD:8553948
Molecular Function	GO:0017174	glycine N-methyltransferase activity	Gnmt	IMP		Rat	PMID:18501206|RGD:7242952
Molecular Function	GO:0042802	identical protein binding	GNMT	IPI	UniProtKB:Q14749	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	GNMT	IPI	UniProtKB:Q14749	Human	PMID:25502805
Molecular Function	GO:0042802	identical protein binding	GNMT	IPI	UniProtKB:Q14749	Human	PMID:26871637
Molecular Function	GO:0042802	identical protein binding	GNMT	IPI	UniProtKB:Q14749	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	Gnmt	IPI	UniProtKB:P13255	Rat	PMID:10756111|RGD:12793006
Molecular Function	GO:0042802	identical protein binding	Gnmt	IPI	RGD:2719	Rat	PMID:17158459|RGD:7242951
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P49407	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P49407	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:A0A0S2Z5F2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P49407	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P49407	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:O60931-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:O75643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P00492	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P24311	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P31213	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:P49407	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q13066	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q14331	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q494R4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q9UN88	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q9UPQ4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GNMT	IPI	UniProtKB:Q9Y3M9	Human	PMID:32296183
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Molecular Function	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	Gnmt	IDA		Rat	PMID:15347642|RGD:1359070
Cellular Component	GO:0005829	cytosol	GNMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Gnmt	IDA		Rat	PMID:19239903|RGD:7242903
Cellular Component	GO:0005829	cytosol	Gnmt	IDA		Rat	PMID:6587377|RGD:151356620
Cellular Component	GO:0005829	cytosol	Gnmt	IDA		Rat	PMID:8278367|RGD:1545057
Cellular Component	GO:0034708	methyltransferase complex	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Cellular Component	GO:0005634	nucleus	Gnmt	IDA		Rat	PMID:8278367|RGD:1545057
Biological Process	GO:0006544	glycine metabolic process	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Biological Process	GO:0006544	glycine metabolic process	Gnmt	IMP		Rat	PMID:18501206|RGD:7242952
Biological Process	GO:0005977	glycogen metabolic process	Gnmt	IMP	MGI:MGI:3842652	Mouse	PMID:17937387
Biological Process	GO:0006555	methionine metabolic process	Gnmt	IMP	MGI:MGI:3842652	Mouse	PMID:17937387
Biological Process	GO:0032259	methylation	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Biological Process	GO:0006730	one-carbon metabolic process	Gnmt	IMP	MGI:MGI:3842652	Mouse	PMID:17937387
Biological Process	GO:0051289	protein homotetramerization	GNMT	IPI	UniProtKB:Q14749	Human	PMID:15340920
Biological Process	GO:0051289	protein homotetramerization	Gnmt	IPI	UniProtKB:Q9QXF8	Mouse	MGI:MGI:3852308|PMID:15340920
Biological Process	GO:0051289	protein homotetramerization	Gnmt	IPI	UniProtKB:P13255	Rat	PMID:15340920|RGD:8553948
Biological Process	GO:0006111	regulation of gluconeogenesis	Gnmt	IMP	MGI:MGI:3842652	Mouse	PMID:17937387
Biological Process	GO:0046498	S-adenosylhomocysteine metabolic process	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Biological Process	GO:0046498	S-adenosylhomocysteine metabolic process	Gnmt	IDA		Rat	PMID:15347642|RGD:1359070
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	GNMT	IDA		Human	PMID:15340920
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	Gnmt	IDA		Mouse	MGI:MGI:3852308|PMID:15340920
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	Gnmt	IMP		Rat	PMID:10756111|RGD:12793006
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	Gnmt	IMP		Rat	PMID:12054489|RGD:728472
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	Gnmt	IDA		Rat	PMID:15340920|RGD:8553948
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	Gnmt	IMP		Rat	PMID:18501206|RGD:7242952
Biological Process	GO:1901052	sarcosine metabolic process	Gnmt	IMP		Rat	PMID:18501206|RGD:7242952

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern