Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNRHR
  • Mouse genes Gnrhr
  • Rat genes Gnrhr
  • Zfish genes gnrhr1,gnrhr2,gnrhr4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnrhr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004968	gonadotropin-releasing hormone receptor activity	gnrhr4	IDA		Zfish	PMID:21669817
Molecular Function	GO:0004968	gonadotropin-releasing hormone receptor activity	gnrhr1	IDA		Zfish	PMID:21669817
Molecular Function	GO:0004968	gonadotropin-releasing hormone receptor activity	gnrhr2	IDA		Zfish	PMID:21669817
Molecular Function	GO:0016520	growth hormone-releasing hormone receptor activity	Gnrhr	IDA		Rat	PMID:12050161|RGD:730284
Molecular Function	GO:0005515	protein binding	Gnrhr	IPI	RGD:2266	Rat	PMID:17170088|RGD:1599848
Cellular Component	GO:0005886	plasma membrane	Gnrhr	IDA		Rat	PMID:6291912|RGD:1599851
Biological Process	GO:0097211	cellular response to gonadotropin-releasing hormone	gnrhr2	IDA		Zfish	PMID:21669817|ZFIN:ZDB-PUB-080825-7
Biological Process	GO:0097211	cellular response to gonadotropin-releasing hormone	gnrhr4	IDA		Zfish	PMID:21669817|ZFIN:ZDB-PUB-080825-7
Biological Process	GO:0007623	circadian rhythm	Gnrhr	IEP		Rat	PMID:22356123|RGD:8661632
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Gnrhr	IDA		Rat	PMID:12050161|RGD:730284
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	gnrhr4	IDA		Zfish	PMID:21669817|ZFIN:ZDB-PUB-080825-7
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	gnrhr2	IDA		Zfish	PMID:21669817|ZFIN:ZDB-PUB-080825-7
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	gnrhr4	IDA		Zfish	PMID:21669817
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	gnrhr1	IDA		Zfish	PMID:21669817
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	gnrhr2	IDA		Zfish	PMID:21669817
Biological Process	GO:0008285	negative regulation of cell population proliferation	Gnrhr	IDA		Rat	PMID:14551223|RGD:1599849

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern