Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GOPC
  • Mouse genes Gopc
  • Rat genes Gopc
  • Zfish genes gopc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gopc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005109	frizzled binding	Gopc	IPI	UniProtKB:Q61091|UniProtKB:Q9EQD0	Mouse	MGI:MGI:3688061|PMID:11520064
Molecular Function	GO:0030695	GTPase regulator activity	Gopc	IDA		Mouse	PMID:11162552
Molecular Function	GO:0042802	identical protein binding	GOPC	IPI	UniProtKB:Q9HD26	Human	PMID:11707463
Molecular Function	GO:0140313	molecular sequestering activity	GOPC	IMP		Human	PMID:11707463
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:O43752	Human	PMID:11384996
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:O43752	Human	PMID:11707463
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P13569	Human	PMID:12471024
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P51790	Human	PMID:12471024
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9R0W0	Human	PMID:19027007
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P05412	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9P0N8	Human	PMID:23818989
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:O43805	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P04004	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P08631	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P15408	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q0P5P2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q12882	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q14849	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q15746	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q16520	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q2TAK8-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q32MK9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q68D86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q6RVD6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q6UWP7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q6ZSB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q7Z2X4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q86YD7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q8IZQ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q8NBB4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q8TBZ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q8WVZ3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q96D59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q96SQ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q99497	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9BWG1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9BYD6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9H1K4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9H9L7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9NTN9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q9P0T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:V9HWD0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:A6NMN3	Human	PMID:26179146
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P13569	Human	PMID:28360110
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q7LBE3-1	Human	PMID:28360110
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q6ZSB9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P13569	Human	PMID:31324722
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P04004	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:P15408	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q6ZSB9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GOPC	IPI	UniProtKB:Q8IZQ8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Gopc	IPI	UniProtKB:Q8R527	Mouse	MGI:MGI:2148898|PMID:11162552
Molecular Function	GO:0005515	protein binding	Gopc	IPI	UniProtKB:Q61091|UniProtKB:Q9EQD0	Mouse	MGI:MGI:3688061|PMID:11520064
Molecular Function	GO:0005515	protein binding	Gopc	IPI	UniProtKB:E9PVD1	Mouse	MGI:MGI:5912860|PMID:28339613
Molecular Function	GO:0005515	protein binding	Gopc	IPI	UniProtKB:O95196	Mouse	MGI:MGI:3693381|PMID:12885772
Molecular Function	GO:0005515	protein binding	Gopc	IPI	PR:O88597	Mouse	PMID:12372286
Molecular Function	GO:0005515	protein binding	Gopc	IPI	PR:Q61625	Mouse	PMID:12372286
Molecular Function	GO:0005515	protein binding	Gopc	IPI	PR:Q61627	Mouse	PMID:12372286
Molecular Function	GO:0042803	protein homodimerization activity	Gopc	IPI	UniProtKB:Q8BH60	Mouse	MGI:MGI:3688061|PMID:11520064
Molecular Function	GO:0044325	transmembrane transporter binding	GOPC	IPI	UniProtKB:P13569	Human	PMID:11707463
Cellular Component	GO:0005737	cytoplasm	GOPC	IDA		Human	PMID:11707463
Cellular Component	GO:0005794	Golgi apparatus	GOPC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	GOPC	IDA		Human	PMID:11384996
Cellular Component	GO:0005794	Golgi apparatus	GOPC	IDA		Human	PMID:23818989
Cellular Component	GO:0005794	Golgi apparatus	Gopc	IDA		Mouse	MGI:MGI:3688061|PMID:11520064
Cellular Component	GO:0016020	membrane	GOPC	IDA		Human	PMID:11707463
Cellular Component	GO:0005886	plasma membrane	Gopc	IDA		Mouse	MGI:MGI:3688061|PMID:11520064
Cellular Component	GO:0032991	protein-containing complex	GOPC	IDA		Human	PMID:18468998
Cellular Component	GO:0045202	synapse	Gopc	IDA		Mouse	PMID:12372286
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	GOPC	IDA		Human	PMID:11707463
Biological Process	GO:0010360	negative regulation of anion channel activity	GOPC	IMP		Human	PMID:11707463
Biological Process	GO:2000009	negative regulation of protein localization to cell surface	GOPC	IMP		Human	PMID:11707463
Biological Process	GO:0007289	spermatid nucleus differentiation	Gopc	IMP	MGI:MGI:2386794	Mouse	PMID:16765935

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern