Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GOT1
  • Mouse genes Got1
  • Rat genes Got1
  • Zfish genes got1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Got1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031406	carboxylic acid binding	Got1	IDA		Rat	PMID:2837211|RGD:2289377
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	GOT1	IDA		Human	PMID:2182221
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	GOT1	IDA		Human	PMID:2241899
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	GOT1	IDA		Human	PMID:2731362
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	GOT1	IDA		Human	PMID:6391741
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Mouse	PMID:4193185
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Mouse	PMID:1914521
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Mouse	PMID:17545671
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Mouse	MGI:MGI:52934
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Mouse	PMID:7444718
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Rat	PMID:10395949|RGD:2289395
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Rat	PMID:2837211|RGD:2289377
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IDA		Rat	PMID:3182856|RGD:632937
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got1	IMP		Rat	PMID:7562489|RGD:1627658
Molecular Function	GO:0047801	L-cysteine transaminase activity	Got1	IDA		Rat	PMID:7113743|RGD:8554626
Molecular Function	GO:0004609	phosphatidylserine decarboxylase activity	Got1	IDA		Mouse	PMID:3242498
Cellular Component	GO:0043679	axon terminus	Got1	IDA		Rat	PMID:2364283|RGD:2289389
Cellular Component	GO:0043679	axon terminus	Got1	IDA		Rat	PMID:7838383|RGD:2289393
Cellular Component	GO:0005737	cytoplasm	GOT1	IDA		Human	PMID:7060339
Cellular Component	GO:0005737	cytoplasm	Got1	IDA		Rat	PMID:7562489|RGD:1627658
Cellular Component	GO:0005829	cytosol	Got1	IDA		Mouse	PMID:4193185
Cellular Component	GO:0005829	cytosol	Got1	IDA		Mouse	MGI:MGI:52934
Cellular Component	GO:0005829	cytosol	Got1	IDA		Rat	PMID:16489927|RGD:13504861
Cellular Component	GO:0070062	extracellular exosome	GOT1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GOT1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	GOT1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	GOT1	HDA		Human	PMID:23533145
Cellular Component	GO:0005764	lysosome	Got1	IDA		Rat	PMID:1765846|RGD:2289376
Cellular Component	GO:0005634	nucleus	GOT1	HDA		Human	PMID:21630459
Biological Process	GO:0006532	aspartate biosynthetic process	Got1	IDA		Mouse	PMID:4193185
Biological Process	GO:0006533	aspartate catabolic process	GOT1	IDA		Human	PMID:2241899
Biological Process	GO:0006531	aspartate metabolic process	Got1	IDA		Rat	PMID:2837211|RGD:2289377
Biological Process	GO:0032869	cellular response to insulin stimulus	GOT1	IEP		Human	PMID:8396422
Biological Process	GO:0071260	cellular response to mechanical stimulus	Got1	IDA		Rat	PMID:26880260|RGD:13504840
Biological Process	GO:0043648	dicarboxylic acid metabolic process	Got1	IDA		Rat	PMID:2837211|RGD:2289377
Biological Process	GO:0043648	dicarboxylic acid metabolic process	Got1	IMP		Rat	PMID:7562489|RGD:1627658
Biological Process	GO:0055089	fatty acid homeostasis	Got1	IDA		Mouse	PMID:17545671
Biological Process	GO:0006094	gluconeogenesis	Got1	IDA		Mouse	PMID:17545671
Biological Process	GO:0019551	glutamate catabolic process to 2-oxoglutarate	Got1	IDA		Mouse	PMID:4193185
Biological Process	GO:0019551	glutamate catabolic process to 2-oxoglutarate	Got1	IDA		Rat	PMID:16489927|RGD:13504861
Biological Process	GO:0019550	glutamate catabolic process to aspartate	Got1	IDA		Mouse	PMID:4193185
Biological Process	GO:0006114	glycerol biosynthetic process	Got1	IDA		Mouse	PMID:17545671
Biological Process	GO:0006114	glycerol biosynthetic process	Got1	IDA		Rat	PMID:17545671|RGD:8553472
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	Got1	IMP		Rat	PMID:26880260|RGD:13504840
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	Got1	IMP		Rat	PMID:29215467|RGD:13504824
Biological Process	GO:0051902	negative regulation of mitochondrial depolarization	Got1	IMP		Rat	PMID:29215467|RGD:13504824
Biological Process	GO:0007219	Notch signaling pathway	Got1	IDA		Mouse	PMID:25446530
Biological Process	GO:0006107	oxaloacetate metabolic process	Got1	IDA		Mouse	PMID:4193185
Biological Process	GO:0006107	oxaloacetate metabolic process	Got1	IDA		Rat	PMID:16489927|RGD:13504861
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	Got1	IMP		Rat	PMID:26880260|RGD:13504840
Biological Process	GO:0046686	response to cadmium ion	Got1	IEP		Rat	PMID:29101047|RGD:13504825
Biological Process	GO:0009743	response to carbohydrate	Got1	IEP		Rat	PMID:29101047|RGD:13504825
Biological Process	GO:0051384	response to glucocorticoid	GOT1	IEP		Human	PMID:8396422
Biological Process	GO:0035902	response to immobilization stress	Got1	IEP		Rat	PMID:25451275|RGD:13504848
Biological Process	GO:1990267	response to transition metal nanoparticle	Got1	IDA		Rat	PMID:28962237|RGD:13504851
Biological Process	GO:0060290	transdifferentiation	Got1	IMP		Rat	PMID:28797105|RGD:13504826

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern