Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GOT2
  • Mouse genes Got2
  • Rat genes Got2
  • Zfish genes got2a,got2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Got2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Got2	IDA		Rat	PMID:14522984|RGD:1582383
Molecular Function	GO:0031406	carboxylic acid binding	Got2	IDA		Rat	PMID:14522984|RGD:1582383
Molecular Function	GO:0019899	enzyme binding	Got2	IDA		Rat	PMID:3997814|RGD:2289392
Molecular Function	GO:0042802	identical protein binding	Got2	IMP		Rat	PMID:12686151|RGD:2289396
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	GOT2	IDA		Human	PMID:2182221
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	GOT2	IDA		Human	PMID:2567216
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	GOT2	IDA		Human	PMID:2731362
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:4193185
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:2139228
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	MGI:MGI:52934
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:1180875
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:1820020
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:869894
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:8274135
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:2571576
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Mouse	PMID:14701727
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Rat	PMID:10395949|RGD:2289395
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IMP		Rat	PMID:12686151|RGD:2289396
Molecular Function	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity	Got2	IDA		Rat	PMID:14522984|RGD:1582383
Molecular Function	GO:0005543	phospholipid binding	Got2	IDA		Rat	PMID:3997814|RGD:2289392
Molecular Function	GO:0030170	pyridoxal phosphate binding	Got2	IMP		Rat	PMID:12686151|RGD:2289396
Molecular Function	GO:0030170	pyridoxal phosphate binding	Got2	IDA		Rat	PMID:14522984|RGD:1582383
Molecular Function	GO:0003723	RNA binding	GOT2	HDA		Human	PMID:22681889
Cellular Component	GO:0009986	cell surface	Got2	IDA		Rat	PMID:11962739|RGD:632939
Cellular Component	GO:0070062	extracellular exosome	GOT2	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	GOT2	HDA		Human	PMID:23533145
Cellular Component	GO:0005743	mitochondrial inner membrane	Got2	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005743	mitochondrial inner membrane	Got2	IDA		Rat	PMID:3997814|RGD:2289392
Cellular Component	GO:0005759	mitochondrial matrix	Got2	IDA		Mouse	PMID:4193185
Cellular Component	GO:0005739	mitochondrion	GOT2	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	GOT2	IDA		Human	PMID:9537447
Cellular Component	GO:0005739	mitochondrion	Got2	IDA		Mouse	MGI:MGI:52934
Cellular Component	GO:0005739	mitochondrion	Got2	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Got2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Got2	IDA		Mouse	PMID:4193185
Cellular Component	GO:0005739	mitochondrion	Got2	IDA		Rat	PMID:11962739|RGD:632939
Cellular Component	GO:0043209	myelin sheath	Got2	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0043204	perikaryon	Got2	IDA		Rat	PMID:7838383|RGD:2289393
Cellular Component	GO:0005886	plasma membrane	GOT2	IDA		Human	PMID:9537447
Cellular Component	GO:0005886	plasma membrane	Got2	IDA		Rat	PMID:24528483|RGD:13506244
Cellular Component	GO:0032991	protein-containing complex	Got2	IDA		Rat	PMID:3997814|RGD:2289392
Cellular Component	GO:0042383	sarcolemma	Got2	IDA		Rat	PMID:23743348|RGD:11041118
Cellular Component	GO:0030315	T-tubule	Got2	IDA		Rat	PMID:23743348|RGD:11041118
Biological Process	GO:0006520	amino acid metabolic process	Got2	IDA		Rat	PMID:14522984|RGD:1582383
Biological Process	GO:0006532	aspartate biosynthetic process	Got2	IDA		Mouse	PMID:4193185
Biological Process	GO:0006533	aspartate catabolic process	GOT2	IDA		Human	PMID:2567216
Biological Process	GO:0006531	aspartate metabolic process	Got2	IMP		Rat	PMID:12686151|RGD:2289396
Biological Process	GO:0043648	dicarboxylic acid metabolic process	Got2	IDA		Rat	PMID:14522984|RGD:1582383
Biological Process	GO:0015908	fatty acid transport	GOT2	IEP		Human	PMID:9537447
Biological Process	GO:0007565	female pregnancy	Got2	IEP		Rat	PMID:27317891|RGD:13506242
Biological Process	GO:0019551	glutamate catabolic process to 2-oxoglutarate	Got2	IDA		Mouse	PMID:4193185
Biological Process	GO:0019551	glutamate catabolic process to 2-oxoglutarate	Got2	IDA		Rat	PMID:16489927|RGD:13504861
Biological Process	GO:0019550	glutamate catabolic process to aspartate	Got2	IDA		Mouse	PMID:4193185
Biological Process	GO:0007595	lactation	Got2	IEP		Rat	PMID:28798692|RGD:13504863
Biological Process	GO:0006107	oxaloacetate metabolic process	Got2	IDA		Mouse	PMID:4193185
Biological Process	GO:0006107	oxaloacetate metabolic process	Got2	IDA		Rat	PMID:16489927|RGD:13504861
Biological Process	GO:0045471	response to ethanol	GOT2	IDA		Human	PMID:9537447
Biological Process	GO:0032868	response to insulin	Got2	IEP		Rat	PMID:23743348|RGD:11041118
Biological Process	GO:0043278	response to morphine	Got2	IEP		Rat	PMID:24528483|RGD:13506244
Biological Process	GO:0014850	response to muscle activity	Got2	IEP		Rat	PMID:22028411|RGD:13506822

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern