Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GP1BA
  • Mouse genes Gp1ba
  • Rat genes Gp1ba
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gp1ba

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P04275	Human	PMID:12183630
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P00734	Human	PMID:12855810
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P04275	Human	PMID:15039442
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P13224	Human	PMID:18674540
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P13224	Human	PMID:18789323
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P21333	Human	PMID:19828450
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P21333	Human	PMID:25666618
Molecular Function	GO:0005515	protein binding	GP1BA	IPI	UniProtKB:P04275	Human	PMID:7721887
Cellular Component	GO:0009986	cell surface	GP1BA	HDA		Human	PMID:23382103
Cellular Component	GO:0009986	cell surface	Gp1ba	IDA		Mouse	PMID:28576878
Cellular Component	GO:0009897	external side of plasma membrane	GP1BA	IDA		Human	PMID:19443707
Cellular Component	GO:0009897	external side of plasma membrane	Gp1ba	IDA		Mouse	MGI:MGI:3847143|PMID:19443707
Cellular Component	GO:0070062	extracellular exosome	GP1BA	HDA		Human	PMID:23533145
Cellular Component	GO:1990779	glycoprotein Ib-IX-V complex	GP1BA	IPI		Human	PMID:1730602
Cellular Component	GO:0016020	membrane	GP1BA	IDA		Human	PMID:15297306
Cellular Component	GO:0005886	plasma membrane	GP1BA	IDA		Human	PMID:15297306
Biological Process	GO:0007596	blood coagulation	GP1BA	IMP		Human	PMID:21037087
Biological Process	GO:0007596	blood coagulation	Gp1ba	IDA		Mouse	MGI:MGI:3773462|PMID:18187573
Biological Process	GO:0007596	blood coagulation	Gp1ba	IMP		Mouse	PMID:20650879
Biological Process	GO:0007596	blood coagulation	Gp1ba	IMP		Mouse	PMID:21037087
Biological Process	GO:0007597	blood coagulation, intrinsic pathway	GP1BA	IPI		Human	PMID:10501658
Biological Process	GO:0007155	cell adhesion	GP1BA	IDA		Human	PMID:9410473
Biological Process	GO:0000902	cell morphogenesis	Gp1ba	IMP	MGI:MGI:2181691	Mouse	PMID:10706630
Biological Process	GO:0042730	fibrinolysis	GP1BA	IDA		Human	PMID:12855810
Biological Process	GO:0007599	hemostasis	Gp1ba	IMP	MGI:MGI:2181691	Mouse	PMID:10706630
Biological Process	GO:0035855	megakaryocyte development	Gp1ba	IMP		Mouse	MGI:MGI:3773462|PMID:18187573
Biological Process	GO:0070527	platelet aggregation	Gp1ba	IMP		Rat	PMID:10727447|RGD:10450868
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling	Gp1ba	IMP		Rat	PMID:12218538|RGD:150527852
Biological Process	GO:0010572	positive regulation of platelet activation	GP1BA	IDA		Human	PMID:1939645
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	GP1BA	IDA		Human	PMID:1939645

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern