Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPC2
  • Mouse genes Gpc2
  • Rat genes Gpc2
  • Zfish genes gpc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GPC2	IPI	UniProtKB:P51654,UniProtKB:Q96SN8,UniProtKB:Q9Y625	Human	PMID:29162697
Molecular Function	GO:0005515	protein binding	Gpc2	IPI	UniProtKB:P21741	Rat	PMID:12084985|RGD:14397565
Molecular Function	GO:0005515	protein binding	Gpc2	IPI	UniProtKB:P63090	Rat	PMID:27671118|RGD:14397577
Cellular Component	GO:0005783	endoplasmic reticulum	GPC2	IDA		Human	GO_REF:0000054
Biological Process	GO:0030182	neuron differentiation	Gpc2	IDA		Rat	PMID:8294498|RGD:728608
Biological Process	GO:0010976	positive regulation of neuron projection development	Gpc2	IDA		Rat	PMID:27671118|RGD:14397577
Biological Process	GO:0007224	smoothened signaling pathway	Gpc2	IMP		Rat	PMID:20231458|RGD:5510027

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern