Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPHB5
  • Mouse genes Gphb5
  • Rat genes Gphb5
  • Zfish genes gphb5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gphb5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:Q96T91	Human	PMID:12045258
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:A8MTA8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:P60508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:Q8N6K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPHB5	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0046982	protein heterodimerization activity	GPHB5	IDA		Human	PMID:12045258
Molecular Function	GO:0031531	thyrotropin-releasing hormone receptor binding	GPHB5	IMP		Human	PMID:12045258
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GPHB5	IMP		Human	PMID:12045258
Biological Process	GO:0002155	regulation of thyroid hormone mediated signaling pathway	Gphb5	IMP	MGI:MGI:3615364	Mouse	PMID:20223276

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern