Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPLD1
  • Mouse genes Gpld1
  • Rat genes Gpld1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpld1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	GPLD1	IDA		Human	PMID:15907827
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	GPLD1	IDA		Human	PMID:17720976
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	GPLD1	IDA		Human	PMID:1833386
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	GPLD1	IDA		Human	PMID:19135435
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	GPLD1	IDA		Human	PMID:2760042
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	Gpld1	IDA		Mouse	MGI:MGI:5447609|PMID:17720976
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	Gpld1	IDA		Mouse	MGI:MGI:5447636|PMID:1833386
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	Gpld1	IDA		Mouse	MGI:MGI:3583476|PMID:15946906
Molecular Function	GO:0004621	glycosylphosphatidylinositol phospholipase D activity	Gpld1	IDA		Rat	PMID:1849823|RGD:8553426
Molecular Function	GO:0004630	phospholipase D activity	GPLD1	IDA		Human	PMID:2760042
Molecular Function	GO:0004630	phospholipase D activity	Gpld1	IDA		Mouse	PMID:9716655
Molecular Function	GO:0005515	protein binding	Gpld1	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0017080	sodium channel regulator activity	Gpld1	IMP		Mouse	MGI:MGI:3703397|PMID:16822939
Cellular Component	GO:0005737	cytoplasm	GPLD1	IDA		Human	PMID:19135435
Cellular Component	GO:0005737	cytoplasm	Gpld1	IDA		Mouse	MGI:MGI:3583476|PMID:15946906
Cellular Component	GO:0070062	extracellular exosome	GPLD1	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	Gpld1	IDA		Mouse	PMID:15946906
Cellular Component	GO:0005576	extracellular region	Gpld1	IDA		Mouse	MGI:MGI:5447636|PMID:1833386
Cellular Component	GO:0005615	extracellular space	GPLD1	IDA		Human	PMID:15907827
Cellular Component	GO:0005615	extracellular space	GPLD1	IDA		Human	PMID:17720976
Cellular Component	GO:0005615	extracellular space	GPLD1	IDA		Human	PMID:17761367
Cellular Component	GO:0005615	extracellular space	GPLD1	IDA		Human	PMID:1833386
Cellular Component	GO:0005615	extracellular space	GPLD1	IDA		Human	PMID:2760042
Cellular Component	GO:0005615	extracellular space	Gpld1	IDA		Mouse	MGI:MGI:5447609|PMID:17720976
Cellular Component	GO:0005615	extracellular space	Gpld1	IDA		Mouse	MGI:MGI:3617276|PMID:16219662
Cellular Component	GO:0005615	extracellular space	Gpld1	IDA		Rat	PMID:1849823|RGD:8553426
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GPLD1	IDA		Human	PMID:1833386
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Gpld1	IDA		Mouse	MGI:MGI:5447636|PMID:1833386
Cellular Component	GO:0005765	lysosomal membrane	GPLD1	HDA		Human	PMID:17897319
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	GPLD1	IMP		Human	PMID:17720976
Biological Process	GO:0071277	cellular response to calcium ion	GPLD1	IDA		Human	PMID:2760042
Biological Process	GO:0071277	cellular response to calcium ion	Gpld1	IDA		Rat	PMID:1849823|RGD:8553426
Biological Process	GO:0071397	cellular response to cholesterol	GPLD1	IMP		Human	PMID:17761367
Biological Process	GO:0071241	cellular response to inorganic substance	Gpld1	IDA		Rat	PMID:1849823|RGD:8553426
Biological Process	GO:0032869	cellular response to insulin stimulus	GPLD1	IDA		Human	PMID:15907827
Biological Process	GO:0071282	cellular response to iron(II) ion	Gpld1	IDA		Rat	PMID:1849823|RGD:8553426
Biological Process	GO:0071467	cellular response to pH	GPLD1	IDA		Human	PMID:17761367
Biological Process	GO:0071401	cellular response to triglyceride	GPLD1	IMP		Human	PMID:17761367
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	GPLD1	IDA		Human	PMID:17761367
Biological Process	GO:0002062	chondrocyte differentiation	Gpld1	IEP		Mouse	MGI:MGI:3583476|PMID:15946906
Biological Process	GO:0002430	complement receptor mediated signaling pathway	GPLD1	IDA		Human	PMID:15907827
Biological Process	GO:0002430	complement receptor mediated signaling pathway	GPLD1	IDA		Human	PMID:19135435
Biological Process	GO:0006507	GPI anchor release	GPLD1	IDA		Human	PMID:15907827
Biological Process	GO:0006507	GPI anchor release	GPLD1	IMP		Human	PMID:17720976
Biological Process	GO:0006507	GPI anchor release	GPLD1	IDA		Human	PMID:19135435
Biological Process	GO:0006507	GPI anchor release	GPLD1	IDA		Human	PMID:2760042
Biological Process	GO:0006507	GPI anchor release	Gpld1	IDA		Mouse	MGI:MGI:3583476|PMID:15946906
Biological Process	GO:0006507	GPI anchor release	Gpld1	IGI	UniProtKB:P80108	Mouse	MGI:MGI:5447609|PMID:17720976
Biological Process	GO:0006507	GPI anchor release	Gpld1	IDA		Mouse	MGI:MGI:3703397|PMID:16822939
Biological Process	GO:0006507	GPI anchor release	Gpld1	IDA		Mouse	PMID:9716655
Biological Process	GO:0008286	insulin receptor signaling pathway	GPLD1	IDA		Human	PMID:18328347
Biological Process	GO:0008285	negative regulation of cell population proliferation	GPLD1	IDA		Human	PMID:19135435
Biological Process	GO:0010897	negative regulation of triglyceride catabolic process	Gpld1	IDA		Mouse	MGI:MGI:3617276|PMID:16219662
Biological Process	GO:0001503	ossification	Gpld1	IEP		Mouse	MGI:MGI:3583476|PMID:15946906
Biological Process	GO:0043065	positive regulation of apoptotic process	GPLD1	IDA		Human	PMID:19135435
Biological Process	GO:0010595	positive regulation of endothelial cell migration	GPLD1	IMP		Human	PMID:17720976
Biological Process	GO:0010907	positive regulation of glucose metabolic process	Gpld1	IDA		Mouse	MGI:MGI:5448527|PMID:20153004
Biological Process	GO:0010983	positive regulation of high-density lipoprotein particle clearance	Gpld1	IMP		Mouse	MGI:MGI:3617276|PMID:16219662
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Gpld1	IDA		Mouse	MGI:MGI:5448527|PMID:20153004
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	GPLD1	IDA		Human	PMID:17720976
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	Gpld1	IDA		Mouse	MGI:MGI:5447609|PMID:17720976
Biological Process	GO:0051047	positive regulation of secretion	Gpld1	IMP		Mouse	MGI:MGI:3703397|PMID:16822939
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Gpld1	IDA		Mouse	MGI:MGI:3617276|PMID:16219662
Biological Process	GO:1900076	regulation of cellular response to insulin stimulus	GPLD1	IDA		Human	PMID:18328347
Biological Process	GO:0009749	response to glucose	GPLD1	IDA		Human	PMID:15907827
Biological Process	GO:0070633	transepithelial transport	Gpld1	IMP		Mouse	MGI:MGI:3703397|PMID:16822939

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern